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How Niramai AI tech changes the breast cancer detection mission

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Corporations Can Close the Gap on Women’s Breast Cancer Screening; in an exclusive report by Gil Bashe, editor-in-chief of Medika Life, FINN Partners’ chair of global health and purpose

March marks Women’s History Month — a time to reflect on the progress and work to be done.

In the realm of medicine, women’s health has long lagged behind men’s, with breast cancer and heart disease diagnoses standing out as two glaring examples of this disparity.

Despite advances in medicine, a hidden and often overlooked challenge persists: the underdiagnosis of breast cancer in women with dense breast tissue.

The Challenge of Dense Breast Tissue

Dense breast tissue is not rare — it affects approximately 40–50 per cent of women.

The condition is characterised by a higher proportion of glandular and fibrous tissue than fatty tissue.

Tissue density increases the risk of developing breast cancer and makes tumors more difficult to detect using traditional mammography.

Mammograms can detect around 90 per cent of breast tumors in the least dense breasts but just 60 percent in the most dense breasts — this dangerous “masking effect” leads to delayed diagnoses and poorer outcomes.

The need for better screening tools for women with dense breast tissue is apparent. Early detection of breast cancer is crucial for improving survival rates.

When cancer is identified at an early stage, treatment options are more effective and less invasive, leading to better patient outcomes.

Research shows that regular screening mammography reduces breast cancer deaths by at least 20 per cent.

However, for women with dense breast tissue, the limitations of mammography call for alternative screening methods to ensure early and accurate detection.

A Personal Mission to Save Lives

Dr. Geetha Manjunath, the founder and CEO of Niramai Health Analytix, didn’t begin her career in healthcare — she’s a computer scientist.

But a devastating personal experience altered her path. Two of her  relatives — just 42 and 38 — were diagnosed with late-stage breast cancer and passed away within six months.

Seeing firsthand the emotional, social, and economic toll pushed her to find a better solution.

“I knew there had to be a better way,” Dr. Manjunath reflects. And she found it by combining artificial intelligence and thermal imaging.

This is the potential power of AI applications – not artificial intelligence – but rather “augmented implementation.”

AI + Thermal Imaging = Early Detection

The Niramai innovative screening method, Thermalytix, uses AI to analyse thermal variations in breast tissue.

Unlike mammograms, this approach doesn’t require radiation, is pain-free, and can detect cancers in stage 0 or stage 1—well before a lump can be felt in self-exam or during a routine health professional visit.

The test is simple: a woman sits in front of a thermal camera, and the AI-driven system analyses the heat patterns in her breast tissue.

The system combines thermal radiomics and vascular radiomics to identify potential cancerous anomalies with remarkable accuracy.

Clinical studies have shown that Thermalytix has a false negative rate of less than 5 per cent.

Compare that to the 50 percent false negative rate of mammograms in dense tissue, and the potential for saving lives becomes pressing.

This technology is FDA-cleared, portable and easy to use—it can be set up in a corporate office or rural clinic and requires only 10–15 minutes per screening.

The test is noninvasive and entirely private: no touch, no see, no physical discomfort—just actionable information.

The results are analysed by AI and reviewed by a health professional, with detailed reports emailed directly to the patient within a day.

While it does not replace mammography, a health professional can now visualise tissue activity variations across the breast region, even in dense breasts.

Bringing Screening to the Workplace

In a game-changing move, Niramai is now conducting corporate-hosted breast health screenings in the US — the first of its kind.

This initiative has the potential to expand access to early detection dramatically.

A single device can screen approximately 30 women per day, and because the test is quick, private, and comfortable, participation rates are expected to increase.

FINN Partners, a global communication agency, became one of the first testing sites for this breakthrough technology.

The agency already has several programmes geared to support employee health, and knowing the heightened cancer risks associated with women with dense breast tissue, it partnered with Niramai to provide screening to employees and family members interested.

“We have come a tremendous way in leveraging technology to advance health, yet we must continue to educate on the importance of preventative medicine and screenings,said Shannon Riggs, managing partner of FINN Portland, who advocated for the in-house screen program.

Unlike a traditional mammogram, the Niramai test is non-contact, radiation-free, and suitable for women of all ages — including those with dense breast tissue.

Niramai technology is portable, making it ideal for deployment not only in hospitals and imaging centers but also in rural areas and underserved communities where access to traditional screening tools is limited.

Overcoming Obstacles to Early Detection

Women with dense breast tissue require supplementary imaging tests, such as ultrasound or MRI, to detect abnormalities that mammograms might miss.

However, accessing these additional screenings presents real challenges:

  • Limited Access: Not all healthcare facilities offer advanced imaging technologies like MRI or ultrasound, especially in rural or underserved areas.
  • High Costs: Supplementary screenings can be expensive, and insurance coverage varies, leading to potential out-of-pocket expenses for patients.
  • Scheduling Delays: High demand for specialised imaging can result in long wait times, delaying diagnosis and treatment.
  • Discomfort and Invasiveness: Some women may find additional imaging procedures uncomfortable or invasive, deterring them from pursuing necessary screenings.

Niramai AI-driven technology removes these obstacles by providing an affordable, portable, and non-invasive alternative.

Its ease of use and high accuracy mean more women can access early detection without the hassle and cost associated with additional imaging.

Speaking to Women — Lisa Heathman’s Story

Lisa Heathman knows firsthand the importance of early detection — and how a twist of fate can change everything.

Lisa was healthy and active when a cycling accident left her with broken ribs and pain in her chest. That injury led her to undergo imaging, which revealed a tumour.

It was early-stage breast cancer — detected before symptoms would have otherwise shown up.

Lisa’s story underscores how early detection can save lives. However, not every woman will experience a lucky accident that leads to a diagnosis.

“That’s why tools like Niramai AI-based screening are so critical — they enable women to take control of their health before symptoms appear.

“Dense breast tissue is like a mask,” Lisa explains. “Mammograms couldn’t see through it. But my accident and an MRI saved my life.”

Niramai AI-driven technology lifts that mask — giving women the advantage of catching cancer early, regardless of breast density.

Empowering Women, Saving Lives

Niramai is more than just a technological breakthrough—it’s a tool for health access. Traditional screening methods have long underserved women with dense breast tissue.

Thermalytix closes that gap, giving women of all ages and tissue types a better shot at early detection and survival.

Dr Manjunath’s mission is ambitious but clear: “My vision is to take this test to every woman on earth and eliminate deaths from breast cancer.”

As we observe Women’s History Month, Niramai innovation is a testament to technology’s power to reshape health outcomes.

Early detection saves lives — and thanks to AI, that life-saving tool is now more accessible than ever.

The future of women’s health is digital, and Niramai is leading the way. The question is no longer whether this technology can make a difference—it already does.

The real question is, how can people’s workplace evolve into a convenient point of care?

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Bridging the metabolic wealth gap: The telehealth platform bypassing insurance to democratise care

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As weight-loss treatments remain locked behind prohibitive paywalls, a new direct-pay initiative is cutting costs in half for low-income patients, and it could provide a new blueprint for health equity.

It is one of the most persistent, frustrating paradoxes in modern healthcare: the medical innovations most capable of addressing widespread chronic conditions are overwhelmingly priced out of reach for the populations most vulnerable to them.

Nowhere is this more evident than in the current landscape of metabolic health and weight management.

As state governments and insurance providers increasingly restrict coverage for advanced weight-loss medications due to skyrocketing costs, a stark dividing line has emerged. Clinical need is no longer the primary factor in who receives treatment. Affordability is.

This financial barrier disproportionately impacts women, who not only face high rates of metabolic conditions but also frequently serve as the primary caregivers in their households.

For a single mother managing childcare, grueling work hours, and the relentlessly rising cost of living, personal well-being is often the first casualty of a tight budget.

These patients are forced into a holding pattern, watching their conditions progress year after year while highly effective, life-changing treatments remain separated from them by a paywall.

Now, a telehealth platform called Amble Health is attempting to dismantle that wall by bypassing the traditional insurance apparatus entirely.

A Structural Shift for Access

Today, Amble Health announced the launch of the Amble Cares Program, a national initiative designed to cut the cost of medical weight-loss treatments in half for low-income Americans.

The programme arrives at a critical inflection point.

Today, roughly one in eight U.S. adults have utilized advanced metabolic medications, according to a recent KFF Health Tracking Poll.

This surge in adoption has driven a fundamental shift in preventative care, but the distribution of that care has been deeply uneven.

Through the Amble Cares Program, eligible patients can access comprehensive medical weight-loss programmes, which may include prescription medications if clinically appropriate, at up to 50 per cent below standard rates.

To ensure the discounts reach the intended demographic, eligibility is determined by an independent, third-party verification partner, based on verified financial need.

The programme explicitly prioritises individuals and families with limited disposable income, including parents and guardians whose financial flexibility is tied up in providing for dependents.

Once verified, patients are connected directly to licensed clinicians to begin treatment immediately, stripping away the friction of waiting periods.

“Healthcare should not be a luxury item,” said Joey Stiver, CEO of Amble Health. At Amble, we believe that a patient’s zip code or income shouldn’t dictate their metabolic health outcomes.

“The Amble Cares Program is our direct response to the cost of living crisis, moving beyond talk of ‘affordability’ to actually delivering it to the people the traditional system has left behind.”

The Direct-Pay Trade-Off

However, this rapid, lower-cost access comes with a significant structural trade-off.

To achieve these price reductions and eliminate the administrative delays, denials, and red tape associated with traditional healthcare, Amble Health operates strictly as a direct-pay platform.

This means participants cannot use outside coverage. The programme does not accept Medicaid, Medicare, commercial insurance, or even HSA/FSA funds.

For some patients, being entirely locked out of utilizing their existing health benefits may present a new kind of hurdle.

But for those who have already found themselves abandoned by traditional coverage networks, facing outright denials, unnavigable prior authorisations, or insurmountable deductibles, the direct-pay model offers a predictable, transparent alternative to a broken system.

Ultimately, the Amble Cares Program is making a bold bet: that the most efficient way to deliver equitable healthcare to disenfranchised populations isn’t to fix the traditional insurance system, but to innovate entirely around it.

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UK report warns against ‘financial half measures’ for women’s health

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The Women and Equalities Committee (WEC) has warned against “financial half measures” on women’s health as the government published its response to the report.

Ministers launched the renewed Women’s Health Strategy in April after the committee’s March report concluded it was not convinced that the menstrual and gynaecological needs of young women and girls had been sufficiently prioritised in wider healthcare reforms.

It followed the committee’s 2024 “medical misogyny” report, which found women with painful reproductive health conditions such as endometriosis, adenomyosis and heavy menstrual bleeding were frequently finding their symptoms “normalised” and their “pain dismissed” when seeking help.

In both reports, MPs called on the government to recognise the benefits of increased investment in early diagnosis and treatment of women’s reproductive health conditions and provide additional funding needed to transform the support available to millions of women.

In its response, published on 26 May as a command paper, the Department of Health and Social Care outlined action on reducing gynae waiting times, ensuring procedures are conducted with women’s full consent and adequate pain relief, and improving access to contraception for menstrual healthcare in line with the committee’s recommendations.

It said: “The government agrees with the committee’s overarching findings and recommendations for improving women’s health outcomes and experiences.

“We acknowledge the impact that menstrual health conditions can have on women’s lives, relationships, and participation in education and the workforce.

“We recognise that more needs to be done to support women with menstrual health conditions, particularly around listening to women, improving information and education, and enhancing patient experience.”

However, there was no commitment to increase school nurse provision, no measurable actions and targets on countering online misinformation, no new commitments to end inappropriate censorship of women’s online health content, and no further initiatives on tackling racial discrimination or understanding the menstrual wellbeing needs of young disabled and Deaf women.

The response comes after analysis by The Times suggested the government is allocating 60 per cent more funding to its men’s health strategy than to its renewed strategy for women’s health.

Sarah Owen, chair of the Women and Equalities Committee and Labour MP, said: “WEC’s 2024 ‘medical misogyny’ report warned 18 months ago of women in unnecessary pain and undiagnosed for years and called on the Government to recognise the benefits of increased investment in early diagnosis and treatment.

“Our follow up report this March cautioned girls’ and women’s health are not being sufficiently prioritised in system-wide NHS reforms, while initiatives which have proven to be successful in reducing waiting lists and improving women’s healthcare access, such as women’s health hubs, risked being scaled back or discontinued.

“While it’s welcome to see a focus on tackling ‘medical misogyny’ in April’s renewed Women’s Health Strategy and an emphasis on women’s voices being heard, this must be backed by adequate funding, not financial half measures, particularly when compared to men’s health.

“Significant questions remain following today’s response publication over the adequacy of investment being provided, including for workforce training, menstrual health education in schools, research and additional ring-fenced funding for women’s health hubs to deliver services within the emerging neighbourhood health framework.

“There are both opportunities and risks when it comes to increasing use of technology in women’s healthcare.

“As the Committee’s report set out, social media companies should be held to account for inappropriate and disgraceful ‘shadow banning’ censorship of important women’s health content and there should be a rigorous approach to tackling the risks from ineffective, unsafe and exploitative for-profit FemTech apps.

“The Government should take the problem of ‘shadow banning’ more seriously.

“A strategy which does not fully address the concerns set out in WEC’s report, alongside measurable actions and timescales, will only scratch the surface of the issues facing women’s health.

“WEC will keep a close eye on progress and continue to push for long overdue tangible change for women and girls.”

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Early PET scan could chemo response in aggressive breast cancer – study

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An early PET scan after one cycle of chemotherapy may help predict how aggressive breast cancer responds to treatment, a study suggests.

Research led by The Institute of Cancer Research, London and King’s College London suggests that an early scan taken after one cycle of chemotherapy could help predict how well a patient’s cancer will respond to treatment.

The study focused on patients with triple-negative breast cancer (TNBC), an aggressive form of the disease in which cancer cells lack receptors for the hormones oestrogen and progesterone, as well as the HER2 protein.

Patients with TNBC are usually treated with chemotherapy prior to surgery. While many respond well, residual disease at surgery, typically around six months later, is associated with a significantly poorer prognosis. Identifying people sooner who are unlikely to respond remains a major clinical challenge.

The research explored whether using PET imaging shortly after treatment begins, rather than relying only on MRI scans later in the treatment process, could provide earlier insight into how a patient’s cancer is responding. Twenty-two patients were recruited, with fourteen undergoing FDG-PET scans before treatment and after the first cycle of chemotherapy.

The findings, published in Clinical Cancer Research, showed that changes seen on PET scans after just one cycle of chemotherapy were strongly associated with subsequent response, including whether there was no detectable cancer, known as a complete response, by the end of treatment. Importantly, early PET response showed stronger associations with treatment outcomes than standard mid-treatment MRI scans in this study.

Being able to identify patients who are not responding well at an early stage could allow clinicians to adjust treatment sooner or consider alternative approaches. These findings may also support future strategies to better tailor treatment intensity to individual patients.

The study also compared two types of PET tracers, FDG and FLT, to determine which was most suitable. While both met the study’s technical criteria, FDG-PET was selected for further evaluation due to its better image quality, greater consistency and wider use in clinical practice.

The research also explored how imaging changes after just one cycle of chemotherapy relate to the body’s immune response to treatment. Biopsies taken before and after the first cycle of chemotherapy showed that an increase in immune cells within the tumour was strongly associated with both early PET changes and improved treatment outcomes.

The researchers emphasise that these findings now need to be validated in larger studies. Future work will aim to confirm these results in broader patient groups and explore more accessible imaging approaches, such as ultrasound, alongside PET and MRI.

Sheeba Irshad, professor of cancer immunology at King’s College London and lead of the Breast Cancer Now KCL Research Unit, said:

“In patients who had PET scans both before treatment and after the first cycle, we found that this early scan could predict whether they were likely to achieve a complete response by the end of treatment. These findings highlight the potential of early imaging to guide treatment decisions, and now need to be validated in larger, modern clinical trials.”

Andrew Tutt, professor of breast oncology at The Institute of Cancer Research, London, said:

“Research that helps us determine early who is already benefitting from standard neoadjuvant chemotherapy and who might benefit from clinical trials to find better treatments is vital. This study shows that FDG-PET may have great value in this regard. We hope to be able to design studies that further investigate and validate these findings.”

The study was supported by funding from King’s College London and Guy’s and St Thomas’ NHS Foundation Trust, Breast Cancer Now, Cancer Research UK, and Guy’s and St Thomas’ Charity.

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