Fertility
Fertility clinics under pressure to pause price rises, as cost of living crisis forces patients into debt
More than 90 per cent of fertility patients in the UK have experienced financial worries in relation to treatment
UK fertility clinics have come under pressure to pause price rises, as growing numbers of patients are getting into debt to pay for treatment.
Dr Catherine Hill, Fertility Network UK’s head of policy and public affairs, spoke of a “toxic combination” of the cost of living price hikes and the lack of access to NHS-funded fertility treatment, which could leave patients priced out of the market, with potentially serious repercussions for their mental health.
She said couples are facing “mountains of debt” and some are being pressured into making unwelcome treatment choices.
“Patients should not be facing the decision to discard much wanted embryos because they can’t afford the costs of transferring them or storing them. Patients should not be swayed into donating their eggs or having a double embryo transfer rather than the recommended single transfer in order to afford necessary medical healthcare. And patients should not be having to forego monitoring scans or genetic testing to avoid inherited conditions in order to be able to continue with treatment,” Hill explained.
“With half of UK fertility patients unable to afford to move forward with fertility treatment and others considering potentially risky options to be able to access care, this is a crisis point for fertility patients and the sector.
“It is a scandal for the country that pioneered IVF over 45 years ago and it is rooted in the lack of equitable access to NHS-funded fertility care and the continuing steep cost of private treatment.”
The charity is calling for fertility clinics to expand the financial support for patients struggling to afford treatment, urging private providers to be clear on treatment costs.
“We urge clinics to consider halting price hikes or providing payment pauses for patients facing their stored embryos being destroyed and, for those who don’t already, to offer payment plan packages.”
Clare Ettinghausen, director of strategy and corporate affairs at Human Fertilisation and Embryology Authority (HFEA), said the regulator is concerned that patients are limited in their treatment choices by the cost of storage or transfer of embryos.
“Most fertility patients pay for their own treatment and this can be very expensive, as well as emotionally difficult,” she said.
“Clinics should be giving clear information about the costs of treatment, including any future costs such as storage or embryo transfer to patients before they start treatment.”
A survey by Fertility Network UK of almost 200 patients found that 95 per cent had experienced financial worries in relation to fertility treatment, with 92 per cent saying these problems had been exacerbated by the cost of living crisis.
Half of respondents said a combination of the cost of living crisis, the lack of NHS-funded help and the high cost of private care meant they were unable to move forward with fertility treatment.
One patient, who asked to remain anonymous, told the charity: “We have one frozen embryo left that we spent two years saving for. We can’t afford to have that embryo transferred. Next month the year’s freezing expires so we will have to try and find the money to pay for another year’s freezing or our embryo will be destroyed. Sadly, we can’t do anything more, we are broke.”
Prices for fertility treatments have risen in recent months, in line with inflation throughout the rest of the economy. Many IVF providers said they had no choice but to increase treatment costs to stay afloat.
Dr Suvir Venkataraman, director at Harley Street Fertility Clinic, said: “All clinics are being hit by inflation and as a result price increases are inevitable.
“Harley Street Fertility specialise in treating patients with a complex medical history who seek the optimum treatment for their condition and fertility challenges. Achieving leading success rates as a clinic often leads to higher initial treatment costs.
“Our sample storage fees had remained unchanged since we opened, 13 years ago. However, owing to cost increases in equipment and liquid nitrogen supplies, regrettably, we had to increase our fees for the first time this year.”
Venkataraman said Harley Street Fertility Clinic partnered with three finance companies to offer patients different support packages.
“We work with three partners currently to provide customers with choice and we are open to new financial products from our finance partners. However, as a boutique clinic we are limited in our options. We call on the government and finance industry to come up with improved support for patients.”
Victoria Sephton, chief medical director at Care Fertility, said: “We try and ensure that the costs and treatment pathways for patients are clear at the start of treatment by providing in depth information through our website, information events and social channels.
“We also offer comprehensive fertility assessments for both men and women for those at the start of their fertility journey. By offering patients a clear understanding of their path to parenthood from the start, we allow them to effectively manage the costs associated with their treatment plan.”
Fertility benefits providers, which have grown exponentially since 2019, are pressing employers to do more to support people looking to pursue fertility treatment.
Leila Thabet, VP of global growth at Maven Clinic, said: “Fertility benefits have already become a must-have among US employers, and we’ve started to see many multinational companies with employees in the UK embracing these benefits.
“Over 60 per cent of IVF treatment is privately funded in the UK and, certainly, during a cost of living crisis, employers who prioritise investment in this critically under-supported phase of life will be substantially easing the pressure on their employees, given the prohibitive cost of care for many families.
“Employers have historically focused on the financial aspect of fertility benefits, but there is a growing realisation that, although this is vital, it’s not the only role employers can play, as employees also lack critical, emotional and clinical support through the fertility journey.”
Jenny Saft, co-founder and CEO of the fertility benefits platform Apryl, added: “Fertility treatments can be financially demanding. In a situation where individuals are already grappling with increased living costs, the additional burden of fertility treatment expenses can be overwhelming.
“Fertility benefits play a vital role not just as a healthcare provision but as a crucial support system for couples and individuals embarking on their fertility journey. With the financial pressures that the cost of living crisis brings, these benefits become even more significant.”
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Insight
Chemotherapy may significantly impair fertility and ovarian function, study suggests
Chemotherapy may reduce ovarian function and fertility in women, a recent study suggests.
The research examined how cancer treatment affects ovarian tissue, hormone production and ovarian reserve (the egg supply available for reproduction).
The authors found that some chemotherapy drugs can trigger oxidative stress (cell damage from unstable molecules) and apoptosis (programmed cell death) in ovarian follicles.
These effects can reduce ovarian volume, destroy growing and dormant follicles, and speed up depletion of the egg reserve.
Damage to the ovarian microenvironment can disrupt hormone production and the balance needed for follicle maturation and ovulation, increasing the risk of diminished fertility or premature ovarian insufficiency (early loss of ovarian function before 40).
The findings suggest women of reproductive age receiving chemotherapy may face reduced ovarian reserve, impaired fertility and earlier menopause compared with those not treated.
The researchers said the results support integrating fertility risk assessment and preservation into cancer care.
Clinicians should discuss possible impacts before treatment and consider referrals to fertility specialists.
Preservation options include egg or embryo freezing, ovarian tissue storage or ovarian suppression therapies, depending on individual needs.
The authors called for research into protective strategies to limit ovarian damage during treatment, and long-term studies tracking fertility outcomes in survivors.
Understanding how different chemotherapy types affect the ovaries will be key to personalised onco-fertility care.
Fertility
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Insight
‘Rejuvenated’ eggs raise hopes for improved IVF outcomes
Scientists say they have ‘rejuvenated’ human eggs, in work that could improve IVF success rates for older women.
The team reports that an age-related defect causing genetic errors in embryos may be reversed by supplementing eggs with a key protein.
In eggs donated by fertility patients, microinjection of the protein cut the share showing the defect from 53 per cent to 29 per cent.
The findings were presented at the British Fertility Conference in Edinburgh by researchers from the Max Planck Institute for Multidisciplinary Sciences in Göttingen.
The technique is being commercialised by Ovo Labs, co-founded by professor Melina Schuh, who led the research.
The approach targets problems in meiosis, the process where eggs halve their genetic material before fertilisation.
In older eggs, chromosome pairs can loosen and separate too soon, leading to embryos with too many or too few chromosomes, known as aneuploidy.
The researchers found levels of a protein called Shugoshin 1, which helps hold chromosome pairs together, decline with age. Microinjections appeared to restore this “molecular glue” and reduce errors.
Professor Schuh said: “Overall we can nearly halve the number of eggs with [abnormal] chromosomes. That’s a very prominent improvement.
“Most women in their early 40s do have eggs, but nearly all of the eggs have incorrect chromosome numbers. This was the motivation for wanting to address this problem.
“What is really beautiful is that we identified a single protein that, with age, goes down, returned it to young levels and it has a big effect.
We are just restoring the younger situation again with this approach.
Declining egg quality is a major reason IVF success rates fall steeply with age.
UK figures show an average birth rate of 35 per cent per embryo transferred for patients under 35, dropping to 5 per cent for women aged 43 to 44.
Dr Agata Zielinska, co-founder and co-chief executive of Ovo Labs, said: “Currently, when it comes to female factor infertility, the only solution that’s available to most patients is trying IVF multiple times so that, cumulatively, your likelihood of success increases.
“What we envision is that many more women would be able to conceive within a single IVF cycle.”
The approach would not extend fertility beyond menopause.
The team is in talks with regulators about a clinical trial.
Dr Güneş Taylor, of the University of Edinburgh, who was not involved, said: “This is really important work because we need approaches that work for older eggs because that’s the point at which most women appear.
“If there’s a one-shot injection that substantially increases the number of eggs with properly organised chromosomes, that gives you a better starting point.”
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