Fertility
Why hormone testing shouldn’t be a one-off

Progesterone is a key hormone in assessing ovulation. FemTech World speaks to Amy Beckley, founder of Proov, to find out how at-home testing could change the way infertility is diagnosed and treated.
Progesterone is a female sex hormone produced mainly in the ovaries following ovulation each month – a crucial part of the menstrual cycle and maintenance of pregnancy.
But when progesterone levels are low, women may have difficulty conceiving and experience uterine bleeding, irregular periods and spotting.
In the US, over six million women – 10 per cent of the female population – aged 15-44 have difficulty getting pregnant or staying pregnant.
“This happens because the US healthcare system is very reactive,” says Amy Beckley, scientist and founder of the home testing company Proov.
After seven miscarriages Beckley and her husband had to actively try conceiving for 12 months before they could see a fertility expert. She was diagnosed with unexplained infertility and the doctors recommended IVF.
“I have a PhD in pharmacology, so I’ve been studying hormone signalling for a long time,” she explains.
“I realised the only thing that was different between my IVF cycles and my natural pregnancies was the fact that after embryo transfer I was put on progesterone supplements to support my luteal phase. This actually matched my previous idea, that I must have a progesterone deficiency causing my short luteal phases.
“But since progesterone in blood fluctuates a lot, one single blood test can’t detect suboptimal levels throughout the implantation window. The research [on progesterone] was there, but nobody had actually come up with a diagnostic test.”
This is when Beckley decided to create Proov Confirm, a urine marker of progesterone and the first and only FDA-cleared PdG test kit to confirm successful ovulation at home.
Her company now offers a suite of diagnostics to provide fertility insights throughout the entire menstrual cycle by allowing women to measure all of the menstrual hormones daily.
Women can then snap a photo of each test within the Insight app and follow the in-app prompts to understand ovulation status, get daily insights and an ovulation insights score, along with a personalised action plan to maximise their wellness.
The idea behind Proov was to empower women with critical information about their ovulation and menstrual cycle, the founder says. “Most women don’t check their hormonal health because there’s no help available,” she adds.
“Women are very savvy and very data-driven. When they have a problem, they try to reach out and get help, but very often there’s nobody on the other end to help them.”
“But it’s very important to look at what your hormones are doing over time. Blood testing misses a lot of issues, so by simply giving women that insight and the actual hormone value we want to help them learn about their cycle and understand it.
“We do everything through our free app and women love this digital approach,” Beckley continues. “They love the idea of seeing numbers and having all the data they need. They love having it stored and having a notification to remind them to take a test the next day.
“It makes things a little bit easier and provides data in a format that’s easily digestible.”
While Proov is already working with a number of American clinics, Beckley hopes to expand their partnerships beyond the US and get approvals in other countries.
“Apart from expanding geographically, we also want to expand into hormonal health in general,” she adds.
“We’re really good at understanding the menstrual cycle to help women get pregnant and we realised that the menstrual cycle is not only important for getting women pregnant, but it’s also important for everyday life.
“Our goal is to support women through heavy, painful periods, PMS and menopause and help them thrive during those hard times.”
Tests are available on proovtest.com and amazon.com.
Fertility
Scottish gov to consider IVF for single women

The Scottish government has launched a national review into whether NHS IVF access should be extended to single women.
The review will also consider whether wider access should be offered to couples who have children from previous relationships.
Health secretary Angela Constance said: “Access to NHS IVF treatment should be fair, timely and reflect the way people’s lives and families look today.”
Most single women are not currently eligible for NHS IVF treatment in Scotland.
Campaigners have welcomed the review.
Katie Rollings of Fertility Action said: “It’s an essential and long-awaited decision that will impact a huge number of people who are struggling to grow their families.
She said there is “no evidence” that having two parents rather than one determines whether a child will thrive.
She added: “What matters is whether a child is loved, safe, supported and has stable, positive relationships around them.”
Figures from the Human Fertilisation and Embryology Authority show Scotland is the only UK nation where NHS-funded IVF cycles outnumber privately funded cycles.
In 2024, more than 6,000 cycles of fertility treatment were carried out among more than 4,000 patients in Scotland. Both figures were slightly lower than the record highs recorded in 2022.
The past 20 years have also seen a rise in the number of same-sex female couples and single women receiving fertility treatment.
In 2024, 625 IVF cycles were carried out for women in same-sex couples in Scotland, with more than one third funded by the NHS.
There were 330 cycles involving single women, of which 50 were NHS-funded.
In England, single women can access IVF through the NHS, although eligibility varies according to the local health trust’s policy.
Current Scottish rules state that couples are eligible if they have been living in a stable relationship for two years and neither partner has been sterilised.
Couples where one partner already has a child can be eligible, but those where both partners have children from previous relationships are not.
Eligibility rules also require a body mass index above 18.5 and below 30, and state that couples must not smoke, drink alcohol or take drugs during treatment. The mother must be under 42.
The Scottish government said the review would also examine consistency of access to fertility preservation, including during cancer treatment, as well as reducing waiting times for donor eggs and sperm.
Same-sex female couples already have access to NHS IVF, but they can face long waits for donor eggs or sperm, as can heterosexual couples who require donor treatment.
The National Fertility Group will lead the review and make “costed, demand-modelled recommendations”, which are due to be published by early summer 2027.
The group will include fertility experts from Scotland’s four NHS-assisted conception units in Glasgow, Edinburgh, Aberdeen and Dundee.
Prof Sarah Martins Da Silva, an NHS consultant and chair of fertility medicine at Dundee University, said there were questions to be answered in a resource-stretched NHS.
“As a fertility specialist I’m never going to be disappointed if the criteria is widened,” she said.
“But with single people, as an NHS clinician looking at the competing demands we have, I’d ask the question about whether being single is a health condition that needs to be funded.”
Da Silva said NHS waiting lists were full of couples who require donated eggs or sperm because of medical conditions including cancer and could face longer waits.
“It’s slightly a disservice to them,” she said.
“There would need to be a real investment and resource without making everybody wait an extraordinary long time.
“With the current financial environment we work in, if you’re talking about new money, where would that come from?”
She said she would welcome changes that encouraged more people to donate eggs or sperm and questioned whether arguments about children needing two parents were necessarily relevant to the debate.
“On the one hand bringing up a child is quite an expensive process, and if you don’t have that support, it can be very difficult.
“But on the other hand, many people start off as a couple and divorce.”
Da Silva also welcomed plans for the review to consider eligibility for couples who already have children, describing the move as “fantastic”.
Fertility
NHS IVF access review launched in Scotland
Fertility
Jersey PMOS clinic a ‘good start’

Jersey is launching a pilot PMOS health check clinic for women to improve follow-up care and access to specialist support.
The clinic will operate at the Assisted Reproductive Unit in St Brelade from October, providing health checks rather than diagnosing or treating the condition.
Women with polyendocrine metabolic ovarian syndrome (PMOS) will need to see their GP before being referred to the service.
Jessica Pinel, chair of PMOS Jersey, described the service as “a good start” but said more could be done.
She said the clinic was in line with draft guidance from the UK’s National Institute for Health and Care Excellence (NICE), which advises annual checks to identify health issues associated with the condition.
Pinel was diagnosed with PMOS in 2023 after spending more than £3,100 on treatment.
She said: “We need to realise that cost may be a barrier to people getting support, even if the cost is going to their GP. But I think we do have to be grateful that we have had this service approved.
“Because the clinic is part of the government health system, it allows for referrals to be made into different pathways like endocrinology, dermatology, so it could actually allow for better support and reduce costs for women with PMOS.
“I think it’s great to see things moving forward and, for women who are newly diagnosed, there’s going to be a more joined-up approach and we’re now taking the long-term health consequences of PMOS more seriously.”
PMOS, which was renamed from polycystic ovary syndrome (PCOS) in May, is a metabolic condition that changes how the ovaries work and affects up to one in eight women, according to the UK’s NHS.
The new name was introduced to reflect the condition’s effects across the body. PMOS has been linked to infertility and weight gain.
The Jersey government said the clinic would help women access further care for PMOS and associated conditions, including type 2 diabetes.
Screening clinic nurse Corrinne Purdy said reviews would take a holistic approach, covering medication, height and weight, sleep, management of the condition, fertility aspirations and mental health.
She said: “We will see whether they’re getting on alright with their medication, how they’re feeling about themselves; we will do height and weight reviews, we will ask them questions about their sleep, how they’re managing their condition.
“We will also speak to them about any particular fertility aspirations and how they’re getting with their mental health as well.”
Purdy said PMOS had been “overlooked” for a long time and that many women struggle with associated symptoms.
The government said women who require specialist management for heavy menstrual bleeding, fertility concerns or other gynaecological conditions would be referred to the appropriate specialist service.
It said existing waiting lists for gynaecology or surgical capacity would not be affected because additional clinical capacity had been identified.
Assistant Minister for Health and Social Services Andy Howell said many women “have been suffering” with PMOS and that the trial was intended to show “that we’re taking them seriously and they’re not going to be dismissed”.
Howell said funding for the clinic would be “managed within the budget that we have at the moment, so it’s not going to cost us any more”.
The Health Department was allocated £381m for 2026 as part of the government’s 2026-2029 budget.
The clinic will also offer investigations including ultrasound scans and endometrial biopsies during the same visit.
Howell said Jersey would base its review of the service on NICE guidance, while Pinel said feedback from women using the clinic would be shared with practitioners to help improve the support provided.
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