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Entrepreneur
Could this start-up turn the tide on ovarian cancer?
Ovarian cancer causes more deaths than any other cancer of the female reproductive system

Nearly 225,000 women are diagnosed with ovarian cancer globally every year, but over 50 per cent of them will not survive. Could this biotech start-up have the solution?
March marks Ovarian Cancer Awareness Month – a chance to put ovarian cancer in the spotlight.
The disease causes more deaths than any other cancer of the female reproductive system and, according to the American Cancer Society, will kill in 2024 12,740 women in the US alone.
Despite this, awareness remains low. New data from Target Ovarian Cancer shows that, while progress has been made, things are not moving fast enough, with 40 per cent of UK women confusing cervical cancer and ovarian cancer.
“We don’t have enough awareness and advocacy around ovarian cancer to elevate the importance of the disease the way we do around breast cancer,” says Oriana Papin-Zoghbi, co-founder and CEO of the biotech start-up AOA Dx.
She believes this is directly linked to the low incidence of the disease – there are about 240,000 new cases of breast cancer in the US every year, compared to just under 20,000 of cases of ovarian cancer.
However, she says: “While we don’t see hundreds of thousands of cases, the percentage of women who die of ovarian cancer is significantly higher than almost any other gynaecological cancer.”
Ovarian cancer’s high fatality rate is largely attributed to a failure to recognise symptoms early on and a series of misconceptions around the disease, such as the idea that ovarian cancer is a “silent killer”.
Papin-Zoghbi agrees. Most of the things we hear about ovarian cancer, she says, are not actually true.
“Around 87 per cent of women with ovarian cancer experience symptoms early on, but they are misconstrued for different things.
“The vague abdominal symptoms that we hear about are commonly mistaken for conditions like endometriosis or irritable bowel syndrome because there is no diagnostic to differentiate them.”
Currently, the only way to confirm an ovarian cancer diagnosis is a tissue biopsy. Most women have a biopsy during an operation called laparotomy, where the surgeons make a large cut down the middle of the abdomen to take samples of tissue.
However, in some cases, doctors have to remove an ovary and have it tested for signs of cancer to confirm a diagnosis.
Papin-Zoghbi and her team at Boston-based AOA Dx are aiming to develop the first early-stage ovarian cancer liquid biopsy diagnostic test, which could significantly cut down fatalities and make the diagnosis process less invasive.
“The fact that 80 per cent of women are diagnosed with stage three and four ovarian cancer is unacceptable. Women need a much better chance,” she says.
“We are hoping that our solution will help elevate our understanding of ovarian cancer.”
The technology has shown over 90 per cent accuracy for detection of ovarian cancer and raises hopes for thousands of women globally. However, it will take time.
“There are certain that are not in our control,” says Papin-Zoghbi.
“It takes up every waking moment to build a company, but we have a strong team and we are very positive about the the path forward.
“We closed a US$17m financing round in October and we are currently focusing on building our lab, developing our product pipeline and conducting our clinical study to validate our technology. In the next couple of years, our aim is to focus on product development and clinical study data ahead of thinking about how we will bring the product to market.
“We’re optimistic – we know we can have a transformational impact on women’s health.”
Entrepreneur
Juno Bio secures US$3.8m for precision diagnostics

Juno Bio has secured US$3.8m to expand its diagnostics platform for vaginal health and reproductive care.
The funding round was led by Ada Ventures, with participation from Artesian, Entrepreneur First and Illumina Accelerator.
The women’s health startup said the seed funding will support the launch of its first CLIA-certified sequencing laboratory in Oakland, California, and a new clinical vaginal microbiome and STI test for healthcare providers.
CLIA certification refers to US laboratory standards for testing human samples used in diagnosis, prevention or treatment decisions.
Dr Leighton Turner, co-founder and chief scientific officer of Juno Bio, said: “The vaginal microbiome is still one of the least understood systems in the body at a clinical scale.
“With our lab, we’re starting to build a measurement standard that clinicians can actually use.
“We believe the level of detail from this kind of testing can meaningfully improve how vaginal healthcare is provided.”
The company is developing precision diagnostics for vaginal health, where patients can experience recurring symptoms, inconsistent diagnoses and treatments based on trial and error.
Juno Bio said bringing testing in-house gives it greater control over the process, from sample handling to results, while allowing it to refine its technology and build what it says is one of the largest datasets focused on the vaginal microbiome.
The vaginal microbiome is the community of bacteria and fungi that naturally live in the vagina. Changes in this balance can be linked to infections, symptoms and wider reproductive health issues.
Juno Bio’s newly launched clinical test examines the wider vaginal microbiome and screens for four common sexually transmitted infections, or STIs.
Rather than looking for a single cause, the test is intended to give clinicians a broader picture of what may be contributing to symptoms.
Juno Bio says this matters because multiple infections can occur at the same time and microbiome changes may be linked to fertility, menopause or recurrent infections.
Dr Anna Powell of Johns Hopkins said: “Vaginal microbiome testing has the potential to significantly reshape how we understand and manage vaginal health, particularly for patients with recurrent or unexplained symptoms.
“While the field is still evolving, advances in sequencing and data interpretation are moving us closer to a future where more personalised, microbiome-informed care can complement existing diagnostic approaches.”
Check Warner, co-founding partner at Ada Ventures, added: “Juno Bio is setting a new standard for how vaginal health is understood and managed.
“What they’ve built at this stage, with this level of capital efficiency, is exceptional.
“We’re proud to support the team as they scale their clinical infrastructure and continue leading innovation in this critically underserved category.”
News
Women’s health draws record $1.55bn in equity as capital spreads beyond the mega-rounds

Women’s health companies raised a record $1.55 billion in disclosed equity in 2025, up 41 per cent year on year, according to W Group’s first Global Women’s Health Investment Report, The Road to the Era of Scale.
The report tracks over 500 funding stories and 164 equity rounds across 15 categories and 30+ countries.
Eighty-five companies raised equity in 2025, the highest single-year count on record. But according to the report, the headline figure isn’t the most significant one.
The bigger shift is in where that capital went and how concentrated it was at the top compared to the year before.
The report also points to a brand new investment category that didn’t exist twelve months ago.
SheMed closed a $50 million Series A this year to build a women-specific GLP-1 and metabolic health platform, the first dedicated raise of its kind.
Alongside the momentum, the report identifies one structural risk that could determine whether 2025’s growth holds: a bottleneck at Series A that’s leaving a number of promising seed-stage companies stuck.
Molly Taylor, head of content at W Group, said: “2025 was the biggest year women’s health has ever had, and the most important finding isn’t the headline number.
“It’s that the money has stopped pooling at the top.
“Capital is reaching more companies, more categories and more countries than ever before. The Era of Scale is real. It’s just not finished, and the Series A gap is where it could stall.
“Closing that gap is the highest-leverage move this ecosystem can make in 2026.”
Read the full report: https://wplatform.co/forms/womens-health-equity-funding-trends-report-2026?utm_source=advocacy&utm_medium=ext_email&utm_campaign=2026-q3-health-report-femtech-world
Entrepreneur
Onto Health acquires diagnostics software company Levy Health

Onto Health has acquired Levy Health, a fertility software company providing precision diagnostics and patient intake for reproductive medicine.
The acquisition, fuelled by Onto Health’s US$20m Series A fundraise in April, supports its plan to build scalable, tech-enabled infrastructure for reproductive medicine.
Onto founder Roohi Jeelani, MD, called it the first of several moves in the company’s expansion strategy in a LinkedIn post, adding that there was “more coming soon”.
She said: “This isn’t just an acquisition, it’s proof of how we’re building Onto: physician-led, tech-enabled, and built to scale without losing the personal touch fertility patients deserve.”
Headquartered in Chicago, Onto Health combines evidence-based fertility care with artificial intelligence-driven diagnostics, clinical automation and longevity science.
AI-driven diagnostics use software to analyse patient information and support clinical decision-making, rather than replace clinicians.
Levy Health, founded in Berlin with US offices in San Francisco, helps medical providers identify endocrine disorders more quickly and helps clinics streamline fertility workups.
Endocrine disorders affect the body’s hormone system, which can influence ovulation, menstrual cycles and fertility.
Co-founder Caroline Mitterdorfer said joining Onto would expand Levy Health’s fertility care tools to more clinics and patients, helping physicians focus on patient care.
Onto opened its first clinic in Chicago in February, with plans for three more in the greater Chicago area.
The company said in April that it would use its new funding, led by Artis and Humania, to support additional operations in the US and expand into the Gulf Cooperation Council.
The Gulf Cooperation Council includes six Arab states bordering the Persian Gulf.
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