Menopause
TaraCares awarded Research and Innovation Fast Start Grant to develop menopause precision medicine platform
The company works with women who participate on a volunteer basis to share their lived experience of menopause

The health tech start-up TaraCares has been awarded the highly competitive Fast Start Award by UKRI Innovate UK to progress research and innovation activities to develop an evidence-led, decentralised precision medicine platform tackling misinformation, misdiagnosis and mismanagement of menopause.
Thanks to Innovate UK, UK’s innovation agency which recognised the criticality of women’s health equity, TaraCares has been able to team up with a carefully selected set of experienced scientists, researchers, engineers, technologists, nutritionists and entrepreneurs who value science and robust research to inform women’s health.
The company works with women who participate on a volunteer basis to share their lived experience of menopause to help other women.
Research partnerships with leading universities is central to its execution strategy, as academia represents an important sector that needs to step up its efforts for mobilising support for staff in menopause transition.
The team behind TaraCares are proud to be collaborating with one such organisation that has stepped up – Sheffield Hallam University with Dr Sally Jackson, chief people officer and pro vice-chancellor (diversity and inclusion) at Hallam.

Funding from Innovate UK has propelled the company’s research into exploring Artificial Intelligence (AI) and machine learning capabilities for its digital health solutions, establishing AI in healthcare research collaboration with the University of Huddersfield.
Reflecting on the partnership, Dr Tianhua Chen, PhD senior lecturer in AI at the School of Computer Science and Engineering, University of Huddersfield, said: “It’s been very pleasant working with Jyoti [TaraCares founder] who I see is a very passionate, determined and Jill-of-all-trades entrepreneur striving to use clinical excellence and cutting-edge AI technologies to promote the understanding of menopause, which is an unmet global need in its awareness, diagnosis and management.”

TaraCares is committed to every single female across the globe to deliver precision medicine for menopause care irrespective of your socio-economic background, health status and type of menopause transition – natural, early, surgical, premature ovarian insufficiency (POI).
The team are breaking new ground and pioneering research in questions that have never been asked because society and governments have not been intentional about female health.
The start-up aims to spearhead a new paradigm of equitable female health where menopause and associated secondary health conditions, cardiovascular disorders, osteoporosis, anxiety and depression among others receive the individualised care that is warranted for long term female health.
If you are a female reading this, you can participate in TaraCares’ ongoing research.
By participating in the study you will be part of a global movement for delivering evidence-based, individualised and integrated menopause care that is accessible and affordable.

To learn more, visit taracares.co.uk or email femalehealth@taracares.co.uk.

Menopause
More research needed to understand link between brain fog and menopause, expert says

Brain fog in menopause is common but still poorly understood, with researchers calling for more work to explain the link and how best to support women.
For a new perspective article published in The Lancet Obstetrics, Gynaecology, & Women’s Health, researchers based in the UK and Australia reviewed the evidence on menopause-related cognitive symptoms. They found that symptoms such as forgetfulness, reduced concentration and brain fog are common during the menopause transition, but are still poorly recognised and under-researched.
More than two-thirds of women report difficulties with memory or concentration over the menopause transition. Multiple factors may contribute to these cognitive symptoms, including hormonal changes, sleep disturbances and psychological and psychosocial stress. Yet, because cognitive symptoms are not widely discussed, they can cause considerable worry, with some fearing they are signs of dementia or undiagnosed neurodevelopmental conditions.
The review paper emphasises that overall cognitive performance for women experiencing menopause-related brain fog typically remains within expected ranges and, importantly, that cognitive symptoms are not linked to an increased risk of dementia.
Professor Aimee Spector of UCL Division of Psychology and Language Sciences, co-author on the paper, said: “Cognitive symptoms such as forgetfulness and ‘brain fog’ are incredibly common during menopause, yet they are often overlooked. Our findings highlight just how complex menopause-related cognitive symptoms are, and how much we still don’t know about what drives them. More targeted research is essential if we are to identify which biological, psychological or lifestyle factors contribute most, and what types of support or treatment are likely to be effective.”
The authors argue that clinicians can play a key role in understanding and validating women’s experiences by asking about the duration of cognitive symptoms, impacts on day-to-day functioning and any other medical or psychosocial factors that could be contributing to cognitive symptoms.
The review also discusses a range of approaches that may ease cognitive symptoms, such as improving sleep quality, engaging in regular aerobic exercise and eating a balanced diet. There is also little but promising research into the impact of psychological therapies targeting cognitive symptoms, with a recent meta-analysis of three cognitive behavioural therapy-based studies showing significant improvements in memory and concentration. The evidence is more mixed for the benefits of hormone therapy on cognitive symptoms during menopause.
The authors identify cognitive symptoms as a major area of unmet need in menopause research. They call for a unified definition of menopause-related cognitive changes and for prospective, longitudinal studies that can track women from pre- to post-menopause. Better understanding of the biological, psychological and social factors that contribute to cognitive symptoms will be crucial for developing effective treatments.
Lead researcher Dr Caroline Gurvich of Monash University said: “There’s a lot of pressure to use objective measures of cognitive decline, like a memory test, for example, in a clinical trial, but the key symptom of brain fog is a subjective experience. So having a definition that acknowledges the key cognitive symptom is critical.”
This is not without precedent – we already use subjective or self-report measures for depression, anxiety and other mental health conditions with great success.
Dr Gurvich said the proposed definition would also validate women’s individual experiences while empowering them through the reassurance that any objective decline in their cognitive ability is subtle.
She added: “This is a decrease in cognitive or learning efficiency, not functionality or capacity. For many women, the perception they are losing capacity is what drives them to stop work or lose the confidence to live fulfilling lives during and after menopause. I hear all the time from women who have gone through menopause that validation would have made a significant difference to their resilience and the approach they took to living with menopause.”
Co-author Professor Martha Hickey of the University of Melbourne and Royal Women’s Hospital said: “Our analysis of the best available research shows that many women experience some degree of cognitive symptoms, such as brain fog, during the menopause transition.”
“But there’s a lack of long-term data, which means that there’s a gap in our knowledge about how the brain fog symptom develops and changes from peri-menopause to after menopause ends. It’s a real gap in our understanding.”
Professor Spector added: “We increasingly see women, typically at the peak of their careers, losing confidence in the workplace, often translating to leaving work or reducing work hours. Having simple strategies to support and retain them at work is also a broader economic issue.”
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