Fertility
Vaginal health test provides first-of-its-kind fertility insights

Women’s precision healthcare company Evvy is launching Fertility Insights within its flagship Vaginal Microbiome Test, which provides insights on the role of the vaginal microbiome in fertility.
The vaginal microbiome is the community of bacteria, fungi, and viruses that live in the vagina – and emerging research highlights its crucial role in reproductive health. An imbalance in the vaginal microbiome can increase inflammation and the risk of infection in the reproductive tract, creating a less hospitable environment for conception.
On the other hand, a microbiome dominated by protective bacteria, such as Lactobacillus crispatus, has been associated with improved fertility, successful implantation, and improved pregnancy outcomes.
Today, one-third of all infertility cases are diagnosed as “unexplained.” While research has long linked vaginal microbial imbalances to infertility, recurrent pregnancy loss, and preterm birth, in-depth vaginal microbiome testing had not been widely accessible.
Evvy is closing this gap by providing first-of-its-kind, fertility-specific insights to help individuals understand and optimise this crucial but often overlooked aspect of their reproductive health.
“The connection between the vaginal microbiome and fertility is one of the most exciting frontiers in reproductive health,” said Dr. Kate McLean, Chief Medical Officer at Evvy.
“We’ve seen compelling research linking specific vaginal bacteria to everything from embryo implantation to pregnancy loss – yet this crucial information wasn’t available to patients or providers in fertility care. By making these insights accessible, Evvy is bridging the gap between cutting-edge science and real-world clinical impact, giving individuals and providers a new tool to support reproductive success.”
Evvy’s test result now includes a new section for fertility insights including a measure of the levels of protective bacteria that are associated with positive outcomes, a measure of overall microbiome diversity, and levels of bacteria specifically associated with negative fertility outcomes, including Fannyhessea, Gardnerella, and Prevotella.
In addition to the insights, Evvy provides access to care protocols to optimise the vaginal microbiome through personalised prescription treatments, lifestyle recommendations, and 1:1 health coaching.
“For too long, fertility has been treated like a black box leaving millions of people searching for answers with no clear path forward,” said Priyanka Jain, co-founder and CEO of Evvy.
“By expanding our Vaginal Microbiome Test to include fertility insights, we’re giving people the power to take control of their reproductive health with comprehensive testing and data-driven, personalised care.”
Fertility
One week left to apply: W Accelerate with Merck KGaA and M Ventures

Applications close 2 September at 12pm BST for W Accelerate with Merck KGaA and M Ventures, a fast-track programme offering startups, scaleups and spinouts in reproductive and maternal health direct access to decision-makers at one of the world’s leading reproductive health companies.
With a single application, innovators connect with Merck KGaA’s partnership team and investment professionals from M Ventures, Merck’s corporate venture arm.
Selected companies will be notified on 11 September and invited to pitch at W Accelerate in London, at One Hundred Shoreditch, on 5 October.
During the event, they will receive a private 30-minute session with Merck and M Ventures leadership, small-group guidance from regulation and investment specialists, an “Ask Merck Anything” roundtable, and access to a VIP networking reception.
Applications are open to companies working on breakthrough solutions across reproductive and maternal health, including fertility, endometriosis, adenomyosis, ovarian health, preeclampsia and pregnancy comorbidities.
Applicants can choose one of three lanes, depending on whether they’re seeking strategic collaboration, investment, or both: Partnership Lane, Investment Lane, or Dual Lane. Direct-to-consumer and over-the-counter products are outside the programme’s scope.
Thang Vo-Ta, CEO & co-founder of Calla Lily Clinical Care and participant of a previous edition of W Accelerate with Merck Healthcare and M Ventures, said: “The opportunity to pitch directly to senior leadership at Merck and M Ventures sparked conversations that became the foundation of relationships leading to our eventual strategic collaboration with Merck. I’ve yet to see another event run with this level of excellence.”
For more information, visit W Group’s website: wplatform.co
Applications close 2nd September 2026, 12pm BST
W Accelerate event: 5th October 2026 at One Hundred Shoreditch, London (travel and accommodation not provided)
Apply here
Fertility
Chelsea FC Women to launch first-of-its-kind player fertility fund

Chelsea FC Women is to launch a fertility fund giving players access to assessments, treatments, counselling and workshops.
The initiative is part of a new partnership with London fertility clinic Fertility Plus, which has been named the club’s official fertility partner.
Chelsea said the fund will be available to every player in its women’s team, with support tailored to individual needs.
Giulia Mazzia, commercial director for Chelsea FC Women, said: “At Chelsea FC Women we are never done pushing for progress for our players and our community.
“This first-of-its-kind partnership with Fertility Plus will open up the conversation about fertility, help to raise awareness for our incredible fanbase and beyond, and give practical support to our players off the field as well as on it.”
Support through Fertility Plus will include fertility assessments and treatments, as well as counselling and workshops.
The partnership will also provide evidence-based information about reproductive health and address misconceptions around fertility.
Chelsea cited previous research on fertility knowledge which found that 41 per cent of respondents actively trying to conceive did not know when their fertile window was.
The club and Fertility Plus plan to provide educational content, resources comparing fertility myths with medical evidence and insights from Chelsea FC Women ambassadors.
Dr Amit Shah and Dr Anil Gudi, co-founders of Fertility Plus, said: “Elite sport asks a lot of women during the very years when fertility matters most, yet it’s a conversation the game has rarely had.
“Partnering with Chelsea FC Women allows us to help change that by giving players, staff and supporters access to trusted fertility expertise and compassionate, consultant-led care.
“We’re proud to work alongside a club that’s setting a new standard for supporting women’s health, both on and off the pitch.
Fertility
Higher doses of common fertility drug may increase pregnancy risks

Higher cumulative doses of common fertility drug clomiphene citrate may increase pregnancy loss risks, according to new research.
Around one in six people experience infertility, with irregular or absent ovulation among the most common causes.
Clomiphene citrate has long been a mainstay of fertility treatment, but Adelaide University research has raised concerns about higher cumulative doses.
The new study found that high doses of clomiphene citrate accumulated over multiple fertility treatment cycles could increase the risk of pregnancy loss.
Lead author associate professor Sheree Boulet said the findings showed a clear dose-response relationship, meaning the risks increased as cumulative exposure rose.
She said: “Women who received higher cumulative doses of clomiphene citrate experienced progressively greater risks of adverse pregnancy outcomes.
“We examined more than 21,000 embryo transfer cycles across four cumulative dose categories and found that increasing the dose did not significantly improve the chance of a live birth.
“Our findings suggest there may be a point where increasing the dose offers little additional benefit while exposing women to greater risk, highlighting the importance of carefully balancing effectiveness with safety when making treatment decisions.”
Supported by the NHMRC and conducted in partnership with Boston University and the Centers for Disease Control and Prevention, researchers analysed 21,004 IVF embryo transfer cycles in the US.
Women receiving cumulative doses of 500mg to 749mg of clomiphene citrate had a 12 per cent higher risk of miscarriage, while those receiving 750mg to 999mg had a 38 per cent higher risk.
Women receiving cumulative doses of 750mg or more were also more than twice as likely to have twins or other multiple births.
Rates of spontaneous abortion, another term for miscarriage, increased as the dose rose.
Researchers also recorded more than a threefold increase in stillbirth at the highest dose, although the finding was not statistically significant because that dose was rare. Larger studies are needed to confirm the association.
The finding is consistent with an earlier Adelaide University study that showed a doubling of neonatal death in pregnancies involving clomiphene citrate. Neonatal death means the death of a baby shortly after birth.
Higher cumulative doses did not improve the chance of a live birth, but did increase twinning, which raises the risk of adverse outcomes for both mother and child.
Clomiphene citrate is one of the world’s most widely prescribed fertility drugs. It has been prescribed to millions of women worldwide since 1967 and remains a recommended first-line treatment for ovulation induction.
The drug is recognised as an essential medicine by the World Health Organization. It works by stimulating the ovaries to release eggs, increasing the chance of pregnancy.
Women who do not respond to lower doses, or who require multiple treatment cycles, may receive progressively higher cumulative doses over time.
The findings build on a series of studies from Adelaide University’s Robinson Research Institute linking clomiphene citrate with increased risks of pregnancy loss, stillbirth, perinatal death and some birth defects.
Experimental studies in mice supported these findings, showing that higher doses reduced successful pregnancies and were associated with pregnancy loss, impaired fetal growth and developmental abnormalities.
Professor Michael Davies, senior researcher and co-author of all the studies, said the latest work builds on more than two decades of Adelaide-led research into the safety of fertility treatments.
He said: “Clomiphene citrate has been used by many women since 1967, but it has never been comprehensively evaluated in large prospective clinical trials.
“Our studies indicate that women respond differently to clomiphene citrate and that increasing cumulative doses may increase the risk of adverse pregnancy outcomes without improving the likelihood of a live birth.
“The findings confirm and extend our previous studies in both human and mouse models which highlight the need to better understand the dose-response relationship and whether more personalised dosing strategies could improve safety.
“Until we can better understand these differences, it remains important that clinicians rigorously follow manufacturer’s safety recommendations and avoid unnecessarily increasing cumulative doses.
“The same questions are now being asked of newer ovulation-inducing medications, so any move away from clomiphene citrate should also be guided by robust evidence rather than assumptions about safety.”
Entrepreneur2 weeks agoApplications close August 18 for Women’s Health Innovation Summit 2026 Innovation Showcase
Menopause2 weeks agoThird of women unaware of perimenopause mental health impact
Fertility1 week agoChelsea FC Women to launch first-of-its-kind player fertility fund
Menopause2 weeks agoMenopausal hormone therapy may lower dementia risk, study suggests
Opinion1 week agoanna perimenopause app launches across 39 markets
Pregnancy2 weeks agoChemicals in plastics may be linked to high blood pressure during pregnancy
Sponsored Content7 days agoThe perfect ‘period pair’: WUKA launches first-ever Teen Starter Kit in Tesco
Wellness2 weeks agoWomen with endometriosis may lose a month’s salary each year – study












