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AI technology could detect pregnancy-related heart disease

A digital stethoscope has been shown to identify twice as many cases of peripartum cardiomyopathy as compared to regular care

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An AI-enabled digital stethoscope could detect pregnancy-related heart disease, new research has shown.

The study, conducted by Mayo Clinic, has found that an AI-enabled digital stethoscope could improve the diagnosis of peripartum cardiomyopathy, a potentially life-threatening and treatable condition that weakens the heart muscle of women during pregnancy or in the months after giving birth.

Researchers used the AI-enabled digital stethoscope that captures electrocardiogram (EKG) data and heart sounds to identify twice as many cases of peripartum cardiomyopathy as compared to regular care.

“We demonstrated for the first time in an obstetric population that AI-guided screening using a digital stethoscope improved the diagnosis of this potentially life-threatening and treatable condition,” explained lead study author Demilade A. Adedinsewo, an assistant professor of medicine in the department of cardiovascular medicine at Mayo Clinic in Jacksonville, Florida.

“This research can change current clinical practice from one that is reactive and symptom-driven to a more proactive approach of identifying pregnancy-related cardiac dysfunction using a simple, low-cost and effective screening tool.

“Earlier diagnosis would facilitate prompt and appropriate management of cardiomyopathy and reduce associated disease and death.”

Peripartum cardiomyopathy is a type of heart failure that can affect women late in pregnancy or after pregnancy. The disease weakens the heart, resulting in a decrease in the amount of blood that is pumped from the heart to other parts of the body.

It is typically diagnosed towards the end of pregnancy or in the months following and may be difficult for health professionals to detect because many of the symptoms are similar to those seen with normal pregnancy, such as shortness of breath and swelling in the feet and legs, according to the American Heart Association.

The rate of peripartum cardiomyopathy is somewhat low in the US, affecting one in every 1,000 to 4,000 pregnancies. However, it is more prevalent in countries like Nigeria, which has the highest reported incidence of peripartum cardiomyopathy worldwide, with it impacting as many as one in 96 pregnancies.

As part of the study, researchers from Mayo Clinic looked at almost 1,200 Nigerian women who were pregnant or had recently had a baby.

Approximately half were evaluated with AI-guided screening using the digital stethoscope and half received usual obstetric care in addition to a clinical EKG. Peripartum cardiomyopathy was detected twice as often among study participants when EKG testing was performed with a digital stethoscope using an AI algorithm, compared to clinical EKG in addition to routine obstetric care.

Overall, four per cent of the pregnant and postpartum women in the intervention arm of the clinical trial had cardiomyopathy compared to two per cent in the control arm, suggesting that half are likely undetected with usual care.

“While we expected AI-guided screening to improve the diagnosis of cardiomyopathy, we did not anticipate the frequency of cardiomyopathy diagnosis would be doubled,” Adedinsewo said.

She added: “Additional large trials enrolling a diverse group of women in other geographic locations are needed to evaluate the impact of AI-guided screening on cardiomyopathy diagnosis as well as its impact on adverse maternal outcomes.”

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Caesarean births overtake natural vaginal deliveries in England for first time

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Caesarean births (surgical births) have overtaken vaginal deliveries in England for the first time, with 45 per cent of births now by caesarean, NHS data show.

Last year, 44 per cent of births were through natural vaginal deliveries and 11 per cent were assisted with instruments such as forceps or ventouse, according to data published on Tuesday covering April 2024 to March 2025. Assisted deliveries use instruments to help the baby out during birth.

More than four in ten caesareans carried out by NHS England were elective, planned operations. For women under 30, natural vaginal birth remained the most common method, while for women aged 30 and over, caesareans were most common. For women aged 40 and over, 59 per cent of births were by caesarean.

In total, 20 per cent of births in 2024-25 were planned caesareans and 25.1 per cent were emergency, with both figures at record highs.

There were 542,235 deliveries in NHS England hospitals during this period, down from 636,643 in 2014-15. One in four births were to mothers aged over 35.

In 2014-15, caesarean deliveries made up 26.5 per cent of births. The increase over the past decade has been attributed to growing numbers of complex pregnancies, linked to factors including rising obesity rates and women waiting until they are older to have children.

Donna Ockenden, one of the UK’s most senior midwives who is leading the inquiry into maternity failures in Nottingham, told BBC Radio 4’s Today programme that the rise was a “complex” and “evolving picture over time”.

She said: “The thousands of women I’ve spoken to want a safe birth above everything else, so we should not vilify or criticise women who make those decisions.”

“In the reality of today’s maternity services – where women are living in poverty, deprivation, they’ve got pre-existing illnesses – obstetricians, midwives, nurses can only do so much, and we don’t always do enough in all cases to optimise women’s health prior to pregnancy.”

Soo Downe, a professor of midwifery at the University of Lancashire, added: “In some cases women are going for caesarean sections as a kind of least-worst option because they don’t really believe they’re going to have the kind of support they need to have a safe, straightforward, positive labour and birth in hospital.

“Or because their birth centres are being closed … or because they go into labour wanting a home birth and the midwife isn’t able to come to them because the midwife’s called somewhere else.

“But for some of them, it becomes the only choice on the table … and for other women, they choose a caesarean because they really want one, and that’s absolutely fine.”

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COVID-19 vaccine significantly reduces risk to pregnant women and baby – study

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Pregnant women who received a Covid-19 vaccine were far less likely to experience severe illness or deliver prematurely, according to a major new study.

The research, drawing on data from nearly 20,000 pregnancies across Canada, found that vaccination was strongly associated with lower risks of hospitalisation, intensive care admission and preterm birth. Preterm birth means delivery before 37 weeks.

These benefits persisted as the virus evolved from the Delta variant to Omicron.

Dr Deborah Money is a professor of obstetrics and gynaecology at UBC and senior author of the study.

She said: “Our findings provide clear, population-level evidence that COVID-19 vaccination protects pregnant people and their babies from serious complications.

“Even as the virus evolved, vaccination continued to offer substantial benefits for both mother and child.”

The findings revealed that vaccinated women were about 60 per cent less likely to be hospitalised and 90 per cent less likely to require intensive care compared with those unvaccinated at the time of infection.

Vaccination was also linked to fewer premature births, reducing the risk by 20 per cent during the Delta wave and 36 per cent during the Omicron wave.

Notably, the analysis found that women vaccinated during pregnancy, as opposed to before pregnancy, had even lower rates of preterm birth and stillbirth.

“But our data suggest there may be added benefits to receiving the vaccine during pregnancy,” said Dr Elisabeth McClymont, lead author and assistant professor in UBC’s department of obstetrics and gynaecology.

The findings arrive amid evolving vaccine guidance for pregnant women.

In the US, the Advisory Committee on Immunization Practices recently did not include a specific recommendation for Covid-19 vaccination during pregnancy in its updated adult immunisation schedule.

Meanwhile, public health officials in Canada and at the World Health Organization continue to recommend that pregnant women receive a Covid-19 vaccine.

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Risk to women of severe bleeding after birth up almost 20% since 2020

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The risk of women in England suffering severe post-birth bleeding has risen to its highest level in five years, prompting fresh concerns about NHS maternity care.

The rate of postpartum haemorrhage, where a mother loses a dangerous amount of blood after delivery, has increased from 27 per 1,000 births in 2020 to 32 per 1,000 this year, a rise of 19 per cent.

NHS England figures analysed by the Liberal Democrats show last year had the largest number of incidents in the five years since records began, with 16,780 cases despite falling birth rates.

This compares with 15,780 in 2023 and 15,230 in 2022.

Helen Morgan is the Liberal Democrats’ health spokesperson.

She said: “The growing risk to mothers of suffering serious and potentially fatal bleeding following childbirth is terrifying.

“We know that severe blood loss contributes to nearly one in 10 maternal deaths [in the UK].

“Every birth involves risk, but rising rates of these incidents will be a source of real fear for women and families across the country.

“It’s completely heartbreaking to see just how many families experience unacceptable injuries and trauma at a time that should be full of excitement and joy.”

The data cover incidents where a woman has lost at least 1.5 litres of blood after giving birth.

While many women bleed after delivery without concern, severe blood loss is the leading cause of maternal death worldwide and accounts for one in 14 maternal deaths in the UK.

The findings add to evidence that NHS maternity care quality and safety are declining.

Last week, Valerie Amos, chair of a government-commissioned investigation into maternity care, said some mothers were receiving unacceptable care that had led to “tragic consequences”.

Obstetricians and gynaecologists say births are becoming more complex, with higher obesity rates and more older mothers raising the risk of complications.

“The reported increase in postpartum haemorrhage is concerning,” said professor Asma Khalil, a consultant obstetrician and maternal-foetal specialist (a specialist in high-risk pregnancy) and spokesperson for the Royal College of Obstetricians and Gynaecologists.

“But it must be understood in the context of births becoming more clinically complex.

“More women are entering pregnancy and birth with factors that can raise the risk of heavy bleeding, for example high blood pressure and a higher body weight, though most will not experience a haemorrhage.”

The Liberal Democrats are urging health secretary Wes Streeting to draw up a “maternity rescue plan” to bring all units up to the Care Quality Commission’s good standard.

In a letter signed by 60 of the party’s MPs, they describe the failure to implement recommendations from previous maternity inquiries as an insult to families harmed by poor care.

Lady Amos said last week it was “staggering” that many of the 750 recommendations made over the last decade had not been put into practice.

A Department of Health and Social Care spokesperson declined to comment directly on the Liberal Democrats’ findings.

They said: “As Baroness Amos set out this week, too many families have been let down by maternity and neonatal services, with devastating consequences.

“That’s why the secretary of state has ordered a rapid review of maternity services and will chair a new national maternity and neonatal taskforce to address deep-rooted issues.”

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