Entrepreneur
Lab-grown human eggs and sperm ‘about seven years away’

Scientists say lab-grown human sex cells could be less than a decade from reality, with major implications for fertility and reproduction.
The technology could, in theory, allow anyone to have biological children, regardless of sex, fertility or age.
Researchers are making rapid progress towards turning adult skin or blood cells into eggs and sperm through a process known as in-vitro gametogenesis (IVG) – a method that reprogrammes cells genetically to become gametes.
The technique typically starts by converting adult cells into stem cells, which are then guided into becoming primordial germ cells – the precursors to eggs and sperm.
These are placed inside a lab-grown organoid (a miniature version of an organ), which provides the biological signals needed to develop them further.
Prof Katsuhiko Hayashi, a developmental geneticist at the University of Osaka, told a meeting of the European Society of Human Reproduction and Embryology in Paris this week that his lab is about seven years away from creating viable human sperm.
Other frontrunners include a team at the University of Kyoto and California-based startup Conception Biosciences, whose Silicon Valley backers include OpenAI founder Sam Altman.
Conception’s chief executive told the Guardian the company is focused on producing clinical-grade human eggs and believes the technology could reverse population decline and open the door to human gene editing.
Hayashi said: “I feel a bit of pressure. It feels like being in a race.
“On the other hand, I always try to persuade myself to keep to a scientific sense of value.”
Hayashi’s lab has already produced baby mice with two biological fathers, suggesting the technique could one day be used by same-sex couples.
He said the lab receives emails from prospective fertility patients about once a week.
He said: “We get emails from [fertility] patients, maybe once a week.
“Some people say: ‘I can come to Japan.’ So I feel the demand from people.”
Matt Krisiloff, chief executive of Conception Biosciences, said: “Just the aspect alone of pushing the fertility clock … to potentially allow women to have children at a much older age would be huge.
“Outside of social policy, in the long term this technology might be the best tool we have to reverse population decline dynamics due to its potential to significantly expand that family planning window.”
Hayashi presented his team’s latest progress at the event, including the creation of primitive mouse sperm inside a lab-grown testicle organoid measuring about 1mm across, and the development of a human ovary organoid – a step towards growing human eggs in the lab.
Inside the artificial testes, Hayashi’s team managed to grow spermatocytes – the precursors of sperm cells – before the cells died.
He said an updated version of the organoid with a better oxygen supply could allow the cells to reach maturity.
Hayashi estimated that viable lab-grown human sperm could be about seven years away.
Creating sperm from female cells, he said, would be “technically challenging, but I don’t say it is impossible.”
He also suggested that his former colleague Prof Mitinori Saitou, based at Kyoto University, or Conception Biosciences could be ahead in the race.
“But they [Conception] are really, really secretive,” he added.
Others agreed with Hayashi’s timescale.
“People might not realise how quickly the science is moving,” said Prof Rod Mitchell, research lead for male fertility preservation in children with cancer at the University of Edinburgh.
“It’s now realistic that we will be looking at eggs or sperm generated from immature cells in the testicle or ovary in five or 10 years’ time.
“I think that is a realistic estimate rather than the standard answer to questions about timescale.”
Prof Allan Pacey, professor of andrology and deputy vice-president at the University of Manchester, said: “I think somebody will crack it. I’m ready for it. Whether society has realised, I don’t know.”
While several labs have successfully produced baby mice from lab-grown eggs, producing viable human eggs has been far more technically difficult.
A recent breakthrough in understanding how eggs stay dormant in the ovary for years could prove key.
Krisiloff declined to share detailed updates but said the company is “making really good progress on getting to a full protocol”.
In the best case, he said, the technology could reach the clinic within five years – though it may take longer.
Most researchers believe years of testing would be required to ensure that lab-grown cells do not carry genetic mutations that could be passed to embryos and future generations.
Some mice created using lab-grown cells have lived normal lifespans and been fertile.
Hayashi said: “We really need to prove that this kind of technology is safe.
“This is a big obligation.”
In the UK, using lab-grown eggs or sperm in fertility treatment is currently illegal.
The Human Fertilisation and Embryology Authority is already considering how safety could be ensured and what testing would be needed before clinical use could be approved.
Mitchell said:“The idea that you can take a cell that was never supposed to be a sperm or an egg and make it into a sperm or an egg is incredible.
“But it does bring the problem of safety. We need to be confident that it’s safe before we could ever use those cells to make a baby.”
Events
Applications close August 18 for Women’s Health Innovation Summit 2026 Innovation Showcase

The Women’s Health Innovation Summit (WHIS) has reminded startups that applications for its 2026 Innovation Showcase close on Tuesday, August 18.
The Showcase gives early and growth-stage companies the opportunity to pitch live on stage to the most influential audience in women’s health, at a summit that convenes more than 1,000 senior decision-makers from across the ecosystem, including payers, providers, pharma, and investors.
Now in its eighth year, WHIS takes place October 13–15, 2026 at Encore Boston Harbor.
The event has built a reputation as the leading platform uniting the full women’s health ecosystem, from health systems and health plans to pharmaceutical leaders and the investors funding the next wave of innovation in the space.
A Direct Line to Funding, Partnerships and Adoption
Companies selected for the Innovation Showcase will present directly to an audience with the capital, clinical expertise and commercial relationships to move deals forward.
Past participants have gone on to secure investor introductions, commercial partnerships and clinical collaborations that started as presentations on the WHIS stage and turned into signed agreements.
Applications Reviewed by an Expert Selection Committee
Submissions are being reviewed by a selection committee of leading investors and industry operators, including:
- Parambir Bhangu, Executive Director, External Innovation & Emerging Science, Organon
- Elizabeth Bailey, Co-Founder & Managing Partner, Foreground Capital
- Karla Loken, Founder, Loken and Associates
- Mané Mikayelyan, Associate Partner, DeciBio
- Anna Valcheva, Founder, Managing Director & CEO, Astra Ventures
- Azin Radsan van Alebeek, Co-founder & General Partner, Emmeline Ventures
WHIS is where the women’s health ecosystem comes together to get deals done,” said Poppy Howard-Wall, Event Director of WHIS.
How to Apply
Early and growth-stage companies across digital health, therapeutics, diagnostics, med device and consumer health are encouraged to apply before the August 18 deadline.
Full details and the application form are available at whisusa.com/attend/start-ups.
Entrepreneur
Women’s Health Week Europe 2026 releases fully populated agenda ahead of October summit

Women’s Health Week Europe 2026 has released its fully populated speaker and session lineup ahead of the event’s return to The Emirates Stadium in London on 7–8 October, with 80+ speakers now confirmed across two dedicated stages.
The programme
The agenda runs across two dedicated stages in parallel, plus two pitch competitions across both days.
The Global Stage opens with a keynote from Merete Clausen (EIF) before moving into sessions on funding trends, AI, the gender data gap, the wearable revolution, and European policy.
Standout sessions include The Age of Digital TransformAItion featuring Nichole Young-Lin (Google), Frida Polli (MIT), and Sapna Shah (Sie Ventures); Lone Wolf or Pack Leader on collaboration versus fragmentation, with Eirini Rapti (Inne), Tatum Getty (Thena Capital), Novo Nordisk, and Jen Roberts-Woods (Borski Fund); and a live debate on whether the women’s health label helps or hinders founders. Day one closes with a keynote from Alison Cave, Chief Safety Officer at the MHRA.
The Scale Stage runs a practical playbook track in parallel, with sessions covering regulatory approval pathways, international expansion, the founder’s legal playbook, PR strategy, and implementing AI into a women’s health business.
The Reverse Pitch flips the usual format: investors and corporates pitch the room on what they are actively looking to fund, acquire, or partner on right now.
Register here and receive a 15% discount on tickets. Redeem with code FEMTECHWORLD
Pitch competitions
The WHW Europe pitch competitions are back, taking place in front of the audience across both days on the mainstage. 16 finalists will compete across two categories: Consumer & Tech on day 1 and Medical Devices & Therapeutics on day 2.
Any company treating a condition that affects women exclusively, differently, or disproportionately is eligible to apply.
Applications and close 28 August 2026.
Previous alumni include Circe, who secured £100k from Innovate UK, BoobyBiome, who closed a £2.5M seed round post-WHW Europe, and Amilis, who secured £1M at London Tech Week after winning at WHW USA 2026.
News
UK femtech investment surges 194% in a decade, research finds

UK femtech investment has risen by more than 194 per cent over the past decade, with deal activity and funding both increasing, new research has found.
The number of deals increased from 18 in 2015 to 53 in 2025, while total funding rose from £9.4m to more than £100m over the same period.
Despite the growth, deal volume and value remain relatively low compared with other parts of the health and care market. Healthcare recorded 69 deals in 2015 and 171 in 2025.
More companies have raised funding over the past decade, while investment values have also increased. Average deal size more than doubled from £527,000 in 2015 to £1.9m in 2025.
Some of the largest funding rounds last year included SheMed at more than £37m, Gaia at £12m, emm at £6.8m and Hertility at £5.9m, with the majority of investors based in the UK.
The research found femtech remains largely early-stage, with seed investments accounting for most deals.
However, venture capital involvement has increased over the past decade, which the research said showed the market was becoming more mature. The number of VC deals rose by 600 per cent.
Vicky Protano, corporate partner at Mills & Reeve, which conducted the research, said: “Over the last decade, the UK femtech ecosystem has expanded, both in terms of deal activity and funding levels. This positive upward trend demonstrates growing investor confidence in femtech and increasing institutional interest in the sector.
“Whilst companies in femtech have relied heavily on angel investors and angel networks to fund their growth ambitions, dynamics are shifting, with more venture capital and PE investors appearing in funding rounds. However, this is just the beginning and there is still more to do. While the sector has experienced strong growth, more work needs to be done to create the right funding environment that is balanced and evenly spread across the UK.”
The research found most deals had taken place in London. While the capital has strengthened its position as the UK’s main hub for femtech start-ups, regional clusters are gradually emerging elsewhere.
Protano said: “Whilst London clearly remains a dominant location for women’s health businesses and investment – both in terms of deal activity and total funding – there is a gradual move to regional expansion outside of the capital, with the South West, South East and the East of England showing increased investment activity in the femtech sector. What the data also highlights is a growing North/South divide, with areas such as the North East, North West, and Yorkshire & Humber significantly underrepresented in the national figures.
“As a national firm, we are also witnessing that similar divide. More investments are being made into women’s health businesses based in the South – and more businesses are, often as a result, locating themselves there, rather than in the North. This is representative of the investment landscape as a whole. However, growth in the femtech sector is being supported by growing regional innovation hubs, the increasing influence of university spin-outs, as well as improved support for start-ups at a regional level.”
She added: “Looking at the positives, we have advised and are continuing to advise on some significant investments in the sector. This further evidences the growing nature of femtech, with sector specific investors also coming to the market.”
Examples include Northern Gritstone’s investment in IVF technology business IVF Micro and Phoenix Private Equity’s investment in London Gynaecology, a provider of private gynaecology clinics.
Other deals include an EKA Ventures-led investment in tech-enabled postnatal care company Hesta Health and Amulet Capital’s acquisition of TFP Fertility.
September marks 10 years since the term “femtech” was coined by Ida Tin, co-founder and chief executive of Clue, one of the first period-tracking apps for women, and founder of think tank Femtech Assembly.
The global market grew to US$9.12bn in 2025 and is projected to reach US$41.4bn by 2034.
Despite that growth, women’s health is still not treated as a priority and significant gender inequalities remain globally in research, trials, diagnosis and treatment, continuing to disadvantage women.
Tin said: “I want men with money and power to get femtech on their radar. The business opportunity is there. The societal economic argument is there.”
Charlotte Lewis, commercial health lawyer at Mills & Reeve who specialises in healthtech and women’s health, said: “For far too long, ongoing disparities in women’s healthcare across the UK have adversely impacted women’s health outcomes, often resulting in prolonged diagnosis and treatment – some of which are well publicised, including the time it takes to diagnose women’s health issues such as endometriosis and rising maternal mortality rates.
“However, we are seeing the landscape beginning to shift in a more positive direction. Our experience is that this is helped by more open discussion and conversations which highlight the issues.
“The data around the sector is valuable and growing and demonstrates the progress that is being made from an investment point of view, creating a better environment where digital innovation can thrive, with a renewed focus on prevention through market-leading consumer-driven products.
“The UK has a real opportunity to transform women’s healthcare into a model of fairness, accessibility, and excellence, and femtech businesses have a crucial part to play in achieving this transformation. As a firm, Mills & Reeve is passionate and dedicated to continuing to influence and support this transformation.”
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