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Researchers to develop AI innovation to improve newborn eye screening

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Cambridgeshire hospital trust has teamed up with a local product innovation consultancy to develop an advanced AI feature for an innovative hand-held newborn eye screening device.

The innovation, being co-developed by  Cambridge University Hospitals NHS Foundation Trust and 42 Technology, aims to further improve the accuracy of diagnosing congenital cataracts.

Cataracts are the leading cause of avoidable childhood blindness worldwide – when babies are examined in maternity wards shortly after their birth.

A prototype of the Neocam ophthalmic imaging device is currently being evaluated in a multi-centre clinical trial funded by the National Institute for Health and Care Research (NIHR) as part of the Digital Imaging versus Ophthalmoscopy (DIvO) study.

Dr Louise Allen is consultant paediatric ophthalmologist at Addenbrooke’s Hospital, Cambridge and Neocam’s inventor.

Allen said: “This novel eye screening technology has been designed to be an affordable, easy-to-use tool to improve the accuracy of diagnosing congenital cataracts in babies.

“The new added AI feature will build on 42 Technology’s previous design and development work, while ensuring the device is even easier for midwives and GPs to use when it is launched commercially.”

This five-year study, involving 30 NHS maternity units across England, aims to determine whether Neocam’s digital imaging technology can improve the detection of congenital cataracts compared with the standard ophthalmoscope test, which uses a bright visible light.

Although the final study outcomes are not due to be reported until 2027, the team has already noted some early positive findings.

For example, several babies have been diagnosed with rare but significant visual conditions that were missed by the standard screening tests being done at the same time.

The new AI feature will enable Neocam to immediately assess the quality of images as they are taken, providing instant feedback to maternity staff on whether a captured image is clear enough for accurate evaluation.

If an image does not meet the quality required, users can simply retake it.

In future, the AI could also potentially be developed to alert the screening midwife or GP to a possible cataract or other eye abnormality but this is not the prime objective for the first AI model.

The software engineering team at 42T will use 46,000 de-identified images from the DIvO study to train the machine learning model.

The aim being to integrate the new edge AI algorithms into the first commercially-available eye screening units so the device can analyse images using its existing processing capability – without added costs, needing any hardware redesign or impacting device performance.

The AI development project is being funded jointly by 42T and with an innovation grant from Addenbrooke’s Charitable Trust (ACT), which also helped fund early development and testing of the first prototype device called CatCam.

Motherhood

Expectations about sleep affect postpartum sleep quality, study finds

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Pregnant women’s expectations about postpartum sleep may predict sleep quality after birth, outweighing prior sleep and psychiatric history, a study suggests.

The findings suggest attitudes and beliefs about sleep during pregnancy could be a modifiable risk factor for postpartum sleep concerns.

They also indicate that, among women expecting the poorest sleep, higher postpartum anxiety may further worsen sleep quality.

Sammy Dhaliwal, lead author is clinical health psychologist and research fellow in the department of obstetrics and gynaecology at the Perelman School of Medicine at the University of Pennsylvania.

Dhaliwal said: “Most pregnant women in our sample anticipated poor postpartum sleep before it occurred, and it was striking that those expectations predicted worse sleep outcomes even after accounting for factors such as prior sleep disorders, psychiatric history, and number of previous births.

“This suggests that attitudes and beliefs about sleep during pregnancy may represent a modifiable target for early intervention before postpartum sleep problems emerge.”

Sleep disturbance affects an estimated 60 to 80 per cent of postpartum women and is linked to a higher risk of depression and anxiety.

Researchers said it is often regarded as an expected part of life after childbirth rather than a health issue that may be addressed earlier.

The study enrolled 432 pregnant women at about 24 weeks of gestation, meaning around 24 weeks into pregnancy.

Participants completed measures of their expectations about postpartum sleep, current sleep quality using the Pittsburgh Sleep Quality Index, and mood using validated depression and anxiety scales.

Assessments were repeated at six, 12 and 24 weeks postpartum.

A subset of 49 women also wore wrist actigraphy devices at six to eight weeks postpartum.

Actigraphy uses a wearable device, similar to a watch, to estimate sleep and wake patterns based on movement.

The results showed that 70 per cent of pregnant women, or 301 of 432 participants, expected poor sleep in the postpartum period.

Researchers found that predicted sleep disruption during pregnancy was a significant predictor of postpartum sleep concerns.

Among first-time pregnant women without prior health concerns, those who expected greater sleep disturbance had significantly more disrupted sleep after birth, measured by both actigraphy and self-report.

Among women who expected the worst sleep quality, higher postpartum anxiety significantly worsened both measured sleep and self-reported sleep, independent of anxiety levels during pregnancy.

Dhaliwal said the findings point to two possible areas for intervention: addressing sleep-related beliefs during pregnancy and treating postpartum anxiety.

Dhaliwal said: “Postpartum sleep disruption is often treated only after problems develop, but our findings suggest there may be an opportunity to intervene earlier during pregnancy.

“Addressing sleep-related beliefs and postpartum anxiety during prenatal and postpartum care may help improve sleep and emotional well-being in new mothers.”

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Mental health

Natural birth pressure harming new mothers’ mental health, research finds

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Pressure to have a natural birth can cause lasting psychological harm when labour does not go to plan, new research shows.

The study found that the messages women receive during pregnancy are directly linked to the shame and self-blame many feel when those expectations are not met.

For the first time, the research provides an explanation for why unmet birth expectations contribute to psychological harm.

Several women involved in the research said they felt they had not given birth “properly”, even when medical intervention had saved their lives.

Rebecca Matthews, lead author and PhD researcher at the University of Reading, said: “These women were not failed by their bodies, they were failed by the messages they were given.

“Birth trauma does not begin with birth. It begins in the ideology sold to women throughout pregnancy.

“For the first time we can explain precisely how, by showing how birth culture creates a moral standard for women that defines what a good mother does and then leaves them to blame themselves when birth does not match that.

“Until we reform the way we prepare women for birth, we will keep seeing the same devastating consequences for mothers and their babies.”

The researchers interviewed 21 first-time mothers in the UK whose births did not go as planned.

From NCT and hypnobirthing classes, to social media to midwives, the researchers heard how women are surrounded by messaging that frames natural, unmedicated vaginal birth as the “gold standard”, not just medically preferable, but as a mark of being a good mother and the first test of maternal worth.

Research shows around half of women report their birth differed significantly from their expectations, and for the women in this study, all of whom experienced exactly that, the psychological consequences were profound.

Women judged themselves against the internalised moral standard that this ideology had created.

The researchers are calling for antenatal education to stop treating one kind of birth as the goal and to present all birth outcomes as equally valid routes to motherhood.

They also call for better postnatal screening for women whose births did not go as expected, specifically targeting the shame, self-blame and identity disruption that this research identifies as mechanisms underlying birth trauma.

The findings align with and extend the conclusions of the Kirkup, Ockenden and Birth Trauma Inquiry reports, all of which documented how the institutional pursuit of “normal birth” contributed to preventable harm.

This research provides the first theoretical explanation of how that ideology generates individual psychological harm and points to antenatal messaging as the primary site of such preventable harm.

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Pregnancy

Wales becomes first UK nation to unite maternity care under a single digital record

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System C has completed the national rollout of BadgerNet Maternity across all seven NHS Health Boards in Wales. This is the first time any UK nation has unified its maternity care under a single digital record and patient-facing app.

With approximately 26,000 babies born annually in Wales, BadgerNet connects maternity information across organisational boundaries in the country.

Expectant parents can access their records, maternity appointments and key updates digitally through a single app, wherever they receive care while clinicians have secure access to the right information at the point of care.

The national three-year agreement across all Heath Boards replaces a patchwork of separate local systems and eliminates the need for paper hand-held notes.

Anthony Tracey is director of digital at Hywel Dda University Health Board, the final of the Welsh Health Boards to go live with BadgerNet.

He said: “The rollout of BadgerNet across Wales is a vitally important step forward in modernising our maternity services and providing a consistent service across the country.

“By giving expectant parents direct access to their information and enabling clinicians to share data more effectively, we are strengthening safety, transparency and consistency in maternity care nationwide.”

For expectant parents, the single digital maternity record transforms how they engage with their care.

Instead of carrying paper notes and repeating information at every appointment, parents can access key details, appointments and updates digitally, supporting more informed conversations and shared decision-making.

The result is greater transparency, fewer administrative frustrations and a more joined-up experience throughout pregnancy and into the postnatal period, regardless of which health board they fall under.

For clinicians and Health Boards, the joined-up approach reduces duplication and streamlines handovers across teams and sites. Information is digitally captured once and made available securely wherever it is needed, helping to minimise errors, reduce time spent tracking down notes and support more efficient multidisciplinary working.

At a national level, linking maternity data across Wales creates a foundation for safer, more consistent care.

Aggregated, standardised information enables earlier identification of trends and variation, supports evidence-based policy decisions and enhances long-term service planning.

With a comprehensive view of maternity activity and outcomes across the country, Wales is now better positioned to raise standards for parents, babies and families.

Guy Lucchi, managing director of healthcare at System C, added: “Delivering a truly national approach across all seven Health Boards is a significant achievement for Wales.

“One shared system means information flows with the patient, not the organisation.

“That reduces duplication, supports earlier identification of risk and frees up valuable clinical time.

“Crucially, linking maternity data at a national level provides powerful insight to drive improvement. Health Boards can benchmark, plan services with greater confidence and ensure resources are targeted where they are needed most, while expectant parents benefit from clearer communication and a more connected experience of care.”

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