Special
Five femtech start-ups leading the fight against cancer
2020 saw an estimated 8.8 million cancer cases in women globally

From early diagnosis to drug discovery, these femtech start-ups are on a mission to develop life-saving solutions to beat cancer and improve women’s lives.
Vara
Vara’s software platform aims to mitigate much of the human subjectivity associated with reading mammography results, reducing the repetitive work screening physicians are routinely subjected to.
The AI technology, developed by processing millions of mammograms, has been trained to identify patterns and help radiologists when reviewing mammograms. However, the more images it sees, the more accurate it gets.
Lattice Medical
The French biomedical start-up Lattice Medical is developing a disruptive bioabsorbable implant for breast reconstruction and breast augmentation.
The procedure uses autologous fat tissues injected into an absorbable implant allowing high volume reconstruction in one surgery.
This absorbable implant is based on fat tissue growing engineering material made of Calais laces and a 3D shell structure delimiting the reconstruction volume. Breasts are entirely reconstructed by the patient’s tissues and no foreign bodies are introduced.
AOA Dx
AOA Dx is a biotech company that focuses on early-stage ovarian cancer detection.
Co-founded by three experts and passionate women’s health advocates, the start-up is developing a “novel” approach to evaluate tumour marker gangliosides in liquid biopsies and develop new diagnostic tests.
AKRIVIS GD, its early-stage liquid biopsy test for ovarian cancer, has proven excellent sensitivity and specificity in a recent study.

Curiva
Curiva is a medical device company aiming to reduce the incidence of cervical cancer with a non-invasive diagnostic patch.
A microneedles mediated diagnostic patch, diaPatch, detects the early onset of cervical cancer, replacing invasive procedures such as the Pap smear and colposcopy.
According to developers, the patch will provide benefits to healthcare professionals for better management of guidelines and improved patient outcomes.
Teal Health
California-based Teal Health is developing the first FDA-approved at-home cervical cancer screening.
Currently, a cervical cancer screening is done in the doctor’s office by a clinician using stirrups and a speculum. By developing a novel self-collection device, the company aims to make it easier for women to collect samples from home.
Its platform aims to increase women’s confidence and adherence to screen for primary HPV and Pap cytology triage and enable conversation and engagement with medical professionals.
Special
Jill Biden visits Imperial on women’s health and AMR mission

Former US first lady Dr Jill Biden visited Imperial College Healthcare NHS Trust and Imperial College London to explore work on women’s health and antimicrobial resistance.
The visit was hosted by professor the Lord Darzi of Denham, who chairs the Fleming Initiative and directs Imperial’s Institute of Global Health Innovation.
Dr Biden, chair of the Milken Institute’s Women’s Health Network, spoke about the impact scientists, clinicians, innovators and investors can have on improving women’s healthcare.
Dr Biden stressed the importance of “collaboration, prevention and education” in improving women’s health globally.
At the museum, Dr Biden and Esther Krofah, executive vice-president of health at the Milken Institute, heard about the worldwide significance of the discovery and the contribution of women who, during wartime Britain, grew penicillin in bedpans to support early experimentation.
The discussion also explored how AMR is a key women’s health issue, with women disproportionately affected in low and middle-income countries, and in high-income settings where women are more likely than men to be prescribed antibiotics.
Dr Biden was shown an architectural model of the Fleming Centre in Paddington, which will bring together research, policy and public engagement to address AMR worldwide.
The second part of the visit brought together Imperial clinicians, researchers and innovators for a roundtable on women’s health priorities, including improving diagnosis, equity in maternity care and support during the menopause transition.
Participants highlighted wide variation in the quality of care for conditions affecting women and called for fairer access to services, with the postcode lottery named as a priority to address.
Professor Tom Bourne, consultant gynaecologist and chair in gynaecology at Imperial’s Department of Metabolism, Digestion and Reproduction, described how AI could improve diagnostic accuracy for conditions such as endometriosis.
Equity emerged as a central theme.
Professor Alison Holmes, professor of infectious diseases at Imperial College London and director of the Fleming Initiative, highlighted persistent gaps in women’s representation in clinical trials, including antibiotic studies, which limits the ability to optimise care and treatments.
Dr Christine Ekechi, consultant obstetrician and gynaecologist at Imperial College Healthcare NHS Trust, drew on national maternity investigations to underline the importance of valid data, meaningful engagement with affected communities and rebuilding trust.
Menopause and midlife health were also identified as priorities for clinical research.
Professor Waljit Dhillo, consultant endocrinologist and professor of endocrinology and metabolism in Imperial’s Department of Metabolism, Digestion and Reproduction, described a new treatment for hot flushes, including for women unable to take hormone replacement therapy, such as those with a history of breast cancer.
The discussion then turned to bringing innovation into health systems. Innovators shared how data and technology are being used to close gaps in women’s health, while noting challenges in accessing funding to grow and scale.
Dr Helen O’Neill and Dr Deidre O’Neill, co-founders of Hertility Health, described predictive algorithms using self-reported data to help diagnose gynaecological conditions at scale.
Embedded into clinical workflows, the technology could reduce waiting times, identify conditions earlier and improve outcomes. They noted how “we have cures for the rarest genetic conditions but don’t even have the answers to common women’s health issues.”
Dr Lydia Mapstone, Dr Tara O’Driscoll and Dr Sioned Jones, co-founders of BoobyBiome, outlined work creating products that harness beneficial bacteria found in breast milk to support infant health.
By isolating and characterising key microbial strains, BoobyBiome has created synbiotics, combinations of beneficial bacteria and the food that nourishes them, to make these benefits accessible to all babies.
Speakers throughout the visit stressed the need to reduce variation in care quality and outcomes for women, strengthen prevention and education, and address power and equity in women’s health.
Professor the Lord Ara Darzi said: “It was a privilege to welcome Dr Biden and the Milken Institute to Imperial to meet some of the outstanding researchers, clinicians and innovators advancing women’s health.
“Imperial’s unique combination of clinical excellence and world-leading research positions us at the forefront of tackling the biggest health challenges facing society and the UK’s ambition for innovation demands nothing less.
“For too long, the health needs of women and girls across their life course have not received the attention they deserve.
“By working together across borders and disciplines, we can transform equitable access to care, accelerate the detection and treatment of disease, and ultimately improve health outcomes for millions of women in the UK and around the world.”
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