Pregnancy
Co-IVF pregnancies may increase risk of serious complications, study suggests

Women using their partner’s egg in co-IVF treatment may face higher risks of complications for themselves and their babies, research suggests.
The review of more than 9,000 patients found increased risks of pre-eclampsia and gestational diabetes, alongside lower birth weights, despite higher live birth rates.
Co-IVF, or reciprocal IVF, lets women in same-sex relationships share the pregnancy journey: one partner provides the egg, while the other carries the baby created with donor sperm.
Elizabeth Choong, first author and an undergraduate student in medicine at the University of Leeds, said: “Numbers of same-sex female couples choosing co-IVF are increasing, so it is vitally important that the risks they face in undergoing this procedure are clearly explained from the outset.
“We hope our research can help keep same-sex couples fully informed before they make any family planning decisions.”
Researchers from King’s College London, Anglia Ruskin University and the University of Leeds analysed five studies comparing co-IVF with conventional IVF, where one partner uses her own egg and donor sperm.
The analysis revealed potential increased risks of pre-eclampsia – a condition that causes high blood pressure and protein in urine during pregnancy – and gestational diabetes, which develops during pregnancy and usually disappears after birth.
IVF cycles among same-sex female couples in the UK rose almost seven-fold between 2008 and 2018, from 320 to 2,151.
Co-IVF is not routinely offered on the NHS, but availability can depend on local policies.
Until late 2024, women undergoing co-IVF faced enhanced screening for hepatitis B, hepatitis C and rubella, costing up to £1,000.
This requirement has now been removed.
Professor Susan Bewley, co-lead of the study and emeritus professor of obstetrics and women’s health at King’s College London, said: “Rates of co-IVF have increased dramatically in the UK.
“It’s important that couples going into the process are aware of potential complications that might happen because the baby is genetically unrelated to the pregnant woman.
“All women deserve full, unbiased information about the extra risks to mother and baby associated with carrying a donor-egg pregnancy – so they can make their own decisions about whether the risk outweighs the benefit.”
The researchers said “ethical considerations must be made to avoid harm whilst respecting patient autonomy and informed consent” when it comes to co-IVF.
While the findings were described as “worrying”, the researchers emphasised that larger studies are needed to confirm them.
Catherine Meads, professor of health at Anglia Ruskin University, said: “These worrying preliminary findings need to be investigated in a much larger-scale study to determine the precise additional risks when women opt to undertake a pregnancy with a donated egg.”
The complications may occur because the pregnant woman’s immune system recognises the embryo as genetically different, similar to risks seen in traditional donor-egg pregnancies.
This immune response can increase the likelihood of pregnancy complications.
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Pregnancy
More than half of women with gestational diabetes face harmful stigma, research reveals

More than half of women with gestational diabetes report stigma from healthcare staff, family, friends and wider society, new research shows.
A survey of 1,800 UK women found widespread emotional distress at diagnosis of the condition, a form of high blood sugar that develops during pregnancy, with effects lasting beyond birth.
Gestational diabetes affects around one in 20 pregnancies in the UK, and the findings highlight the wider toll on women diagnosed with the condition.
The study was funded by Diabetes UK and led by researchers at King’s College London and University College Cork.
Dr Elizabeth Robertson, director of research and clinical at Diabetes UK, said: “Stigma can have a dangerous and devastating impact on pregnant women diagnosed with gestational diabetes, particularly at a time when emotions and anxieties may already be heightened.
“We know that stigma can lead to shame, isolation and poorer mental health, and may discourage people from attending healthcare appointments, potentially increasing the risk of serious complications.
“This research highlights the urgent need for better support systems, based on understanding and empathy to ensure no one feels blamed or judged during their pregnancy.”
More than two-thirds of women, 68 per cent, reported anxiety at diagnosis, while 58 per cent felt upset and 48 per cent experienced fear.
The psychological impact continued beyond birth, with 61 per cent saying the condition negatively affected their feelings about future pregnancies.
Nearly half of women, 49 per cent, felt judged for having gestational diabetes, while 47 per cent felt judged because of their body size.
More than 80 per cent felt other people did not understand gestational diabetes, and more than a third, 36 per cent, concealed their diagnosis from others.
Gestational diabetes stigma was also common in healthcare settings, with 48 per cent reporting that professionals made assumptions about their diet and exercise, and more than half, 52 per cent, feeling judged based on their blood glucose results.
Many women described a loss of control and a sense of disruption during pregnancy.
Nearly two-thirds, 64 per cent, felt they were denied a normal pregnancy, while 76 per cent reported a lack of control over their pregnancy.
More than a third, 36 per cent, felt abandoned by healthcare services after giving birth, and one in four, 25 per cent, continued to experience depression or anxiety postpartum.
Focus group participants described harmful stereotypes, including assumptions that they were ‘lazy’, had ‘poor eating habits’ or ‘lacked willpower’.
Comments from family and friends included remarks such as “should you be eating that?” and “you must have eaten too much, that’s why you have gestational diabetes.”
The researchers are calling for targeted interventions alongside structured emotional support for women during and after pregnancies affected by gestational diabetes, to improve both mental and physical health outcomes.
Professor Angus Forbes, lead researcher from King’s College London, said: “Stigma and emotional distress are far more common in women diagnosed with gestational diabetes than many realise.
“Everyday interactions, even with those who mean well, can deepen this harm, shaping women’s emotional wellbeing and the choices they feel able to make.
“It’s clear that meaningful action is needed to protect women’s mental and physical health.”
Risk factors for gestational diabetes include living with overweight or obesity, having a family history of type 2 diabetes, and being from a South Asian, Black or African Caribbean or Middle Eastern background.
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