News
HPV awareness could save thousands from cervical cancer in low-resource nations – report

A widespread lack of awareness of how a common virus is the primary cause of cervical cancer is leading to thousands of needless deaths every year, concludes a global report.
But embracing more advanced screening tools and the willingness of more women to self-collect health data could be pivotal in addressing the issue.
That is according to a study spanning 12 countries in Europe and Latin America commissioned by the pharmaceutical giant Roche.
Half of those polled had either limited or no awareness of the important role human papillomavirus (HPV) plays in cervical cancer.
HPV is a common virus transmitted through sexual contact and is the primary cause of cervical cancer, responsible for over 99 per cent of cases.
Every year, more than 600,000 women worldwide are diagnosed with cervical cancer and over 340,000 die, with nine in every ten of these women living in low-resource countries.
However, 93 per cent of cervical cancers could be prevented entirely through appropriate screening and HPV vaccination.
The research also demonstrates that with screening rates varying between regions, significant barriers continue to exist that are preventing women from seeking testing.
Respondents in all countries, including both developed and developing nations, reported that concerns about the testing procedure being painful were common – up to 63 per cent in some countries.
Also cited was a sense of discomfort about discussing their sexual history or sexuality with a healthcare provider – up to 57 per cent in some countries.
Joanna Sickler, vice-president, health policy and external affairs at Roche Diagnostics, said: “Thousands of women are needlessly dying from cervical cancer every year. This survey highlights some of the most important barriers to screening, as well as the opportunities we have to prevent disease and improve women’s health.
“With many women reporting being open to new screening tools like self-collection, it has never been more important that communities, health systems, governments and innovators come together to seize this opportunity, and provide the early detection and treatment needed to avoid so many preventable deaths.”
The World Health Organisation is focused on accelerating the elimination of cervical cancer globally, with its latest guidelines recommending HPV DNA testing as primary screening for all women.
Its strategy seeks to ensure that by 2030, 90 per cent of girls are fully vaccinated against HPV by age 15.
It also aims for 70 per cent of women to have been screened using a high-performance test by age 35, and again by age 45, with 90% of those eligible linked to treatment.
This, along with vaccination against HPV, could prevent more than 62 million deaths in the next 100 years.
More than 50 per cent of new cervical cancers occur in women who have never been screened, or have not been screened in the previous five years of their lives.
Many factors can contribute to individuals not participating in cervical cancer screening programs, such as access to healthcare, social and economic barriers, history of traumatic experience, cultural concerns and embarrassment.
The many barriers preventing women from seeking HPV screening could explain the widespread interest in self-testing revealed by the survey.
In European countries, where testing is more routinely available, 57 per cent of women were interested in the opportunity to collect their own samples for testing. This figure rose to 77 per cent in Latin American countries, where routine screening is less readily available because of a lack of infrastructure and available appointment means.
This discrepancy was also reflected in healthcare professional-reported results, which showed 72 per cent of healthcare professionals and government workers in Latin American countries agree their country needs a self-collection programme, compared to 48% in Europe.
Susana Wong, patient advocate and director of Lazo Rosado, Perú, is working to expand access to HPV testing in her country.
She said: “We know very well how to prevent and treat cervical cancer. Now, with HPV molecular tests and vaccination, there really is hope to eliminate this disease. This test gives you the opportunity to live and to live well with your family. It can help women to empower themselves as to their health.”
Men demonstrated even lower levels of awareness compared to women, particularly in Europe.
While 55 per cent to 76 per cent of men in Latin America reported some understanding of HPV, only 35 per cent to 51 per cent of men in Europe had any understanding of HPV at all.
The lower awareness among men highlights the need for educational initiatives to include men, given their potential role in the transmission and prevention of HPV, says the report.
“This survey highlights both the challenges ahead and the significant opportunities we have to advance HPV prevention,” Sickler said.
“By enhancing public education about HPV risks and reimagining how we deliver care, we can drive higher screening rates and make meaningful progress in combating cervical cancer.”
Fighting cervical cancer
Screening for HPV can help identify women who are at risk of developing cervical cancer, so that the disease can be treated early before invasive cancer has a chance to develop.
In poorer countries, women are often diagnosed with cervical cancer at a more advanced stage, where the opportunity for a cure is low.
Last mont, Roche joined the Global HPV Consortium which aims to advance cervical cancer prevention efforts and raise the prominence of early screening and timely detection using high-performance HPV-DNA tests.
Conducted in Q1 2024, the HPV Health Understanding Survey involved 8,703 men and women across 12 countries.
It also measured perceptions among 2,585 healthcare professionals (HCPs) and government professionals of HPV testing availability in their own market.
Mental health
Yoga and omega-3 as effective as therapy for depression in pregnancy, research finds

Yoga and omega-3 supplements may be as effective as talking therapies for pregnancy depression, a major review suggests.
Globally, nearly one in three pregnant women experience depression, but most receive no treatment.
When support is available, women are often directed towards talking therapies such as cognitive behavioural therapy, or CBT, and mindfulness.
CBT is a structured talking therapy that helps people identify and change patterns of thought and behaviour affecting their mental health.
The review examined 115 clinical trials involving more than 12,000 participants across 30 countries.
It found that yoga, massage, omega-3 supplements and bright light therapy were broadly as effective as talking therapies at reducing depression symptoms during pregnancy.
Bright light therapy involves controlled exposure to bright light and is sometimes used to treat mood conditions.
The findings point to the importance of social support and increased connection, as all these approaches offer some element of contact or guided support.
Led by King’s College London, the research brought together trial evidence across every type and format of treatment for antenatal depression under a common framework.
Antenatal depression is depression that occurs during pregnancy.
The study was conducted as part of HappyMums, a European consortium led by the University of Milan that aims to improve mental health support during pregnancy and after birth.
Carmine Pariante, professor of biological psychiatry, said: “This is the most comprehensive analysis of treatments for depression in pregnancy ever conducted, and the findings should prompt a rethink of how we support women during this critical period.
“The evidence is clear that there is no single best approach. What matters is that women have access to a range of options, and that clinicians feel equipped to offer them.”
The researchers said yoga and omega-3 supplements could be legitimate treatment options, rather than stopgaps, for women on waiting lists or those who struggle to access mental health support.
However, the studies differed considerably in design, sample size and how results were measured, so the findings should be interpreted with care.
The team said non-psychological approaches could help women cope with long waits for care without ruling out other treatments alongside them.
Digital and online interventions, including apps and telephone-based support, were also found to be as effective as face-to-face treatment.
Researchers said this could affect how antenatal depression is managed, particularly for women who cannot travel or face long waits for in-person care.
The team found no randomised controlled trials of pharmaceutical treatments for antenatal depression, despite antidepressants being widely prescribed for depression outside pregnancy.
A randomised controlled trial is a study in which participants are randomly assigned to different treatment groups, allowing researchers to compare outcomes more fairly.
Evidence for drug treatment during pregnancy therefore relies on indirect research rather than trials carried out during pregnancy, reflecting long-standing caution around testing medicines in pregnant populations.
NICE guidelines recommend antidepressants for moderate to severe depression in pregnancy, while evidence from outside formal pregnancy trials suggests they can be safe and effective.
However, the researchers said trials are still needed, particularly for women who cannot access or engage with other forms of support.
Riddhi Laijawala, trial manager and PhD student, said: “Depression in pregnancy is common, but it is not inevitable, and it is treatable. What this review shows is that the options available to women are broader than many people realise.
“A yoga class, music therapy, or an online programme may not sound like clinical treatment, but the evidence suggests they can make a real difference, and for many women they may be easier (and quicker) to access than a course of therapy.”
Depression during pregnancy affects an estimated 28.5 per cent of pregnant people worldwide, but only around one in five receives appropriate and timely treatment.
The team said closing this treatment gap should be a priority for health systems because the condition can affect both parent and child.
The HappyMums project is supported by the European Union’s Horizon Europe research and innovation programme.
Hormonal health
Type 2 diabetes rising among young women, experts warn

Type 2 diabetes is rising among women in their 20s in England, with experts warning of a worrying increase since the Covid pandemic.
The rise has largely occurred since the pandemic and is closely linked to increasing obesity levels, according to an analysis of NHS data from 2011 to 2024.
The condition is serious and can lead to severe complications, including heart attacks and strokes.
Diabetes UK said it tends to be more aggressive when it develops at a younger age, raising the risk of serious complications and shorter lives.
The charity said early diagnosis is vital for people at risk to help prevent long-term organ damage.
The condition can sometimes be put into remission through healthy eating and maintaining a healthy weight, without relying on glucose-lowering medicines.
Researchers said newer obesity treatments, including GLP-1 injections and pills, may also help alongside healthy eating advice.
About 90 per cent of the six million people living with diabetes in the UK have type 2 rather than type 1, or insulin-dependent, diabetes.
The risk increases with age, and older adults still account for the largest proportion of new diagnoses.
However, NHS England estimates suggest that 12,000 people under 30 are now living with the condition, with women making up more of the younger cases.
Common symptoms include feeling very tired, urinating more often than usual and feeling thirsty all the time.
Researchers at Imperial College London analysed NHS data from the English National Diabetes Audit to examine trends over time.
The figures showed that cases are falling slightly among older adults, who still account for the largest share of new diagnoses.
However, diagnoses are increasing rapidly among people under 40, with some of the sharpest rises among women aged 20 to 29.
Body mass index at diagnosis has also been rising more quickly among younger adults than in older age groups, pointing to obesity as a likely factor.
Body mass index, or BMI, is a measure of obesity based on a person’s height and weight.
Separate NHS data for England shows obesity rates have worsened since the pandemic, with nearly one in three people now affected.
The largest increases over time have been among younger adults.
Between 2019 and 2025, new obesity cases rose by 16 per cent among people aged 20 to 29 and by almost 20 per cent among those aged 30 to 39.
Rates fell among adults aged 60 to 79 over the same period.
Lead researcher Dr Shivani Misra said: “We think that the earlier onset of severe obesity in young people is increasing their type 2 diabetes risk in early life and pulling down their age at diagnosis.
“This is really worrying given the poor health outcomes from early-onset type 2 diabetes.”
Misra said much of the discussion about rising rates among younger people had focused on ethnic minority groups, which have traditionally been considered at higher risk.
However, the new data suggests the trend extends well beyond those communities.
She added: “We now see that incidence is also increasing in white populations too, showing that this public health challenge is broadening across the generations.”
Diabetes UK said better follow-up care is also needed for mums-to-be diagnosed with gestational diabetes during pregnancy because it raises the risk of developing type 2 diabetes after childbirth.
Some studies have suggested that the risk of developing the condition may also increase after being ill with Covid, although the evidence remains inconclusive.
Wellness
AstraZeneca drug approved for breast cancer in EU

AstraZeneca’s breast cancer drug Etcamah has been approved in the EU as part of a combination treatment for advanced disease.
The European Commission acted on a positive opinion from the Committee for Medicinal Products for Human Use, the Cambridge, England-based drug maker said.
The decision followed positive results from the Serena-6 phase III trial, which showed a 56 per cent reduction in the risk of disease progression in advanced oestrogen receptor-positive breast cancer.
A phase III trial is a large, late-stage study used to assess a treatment’s safety and effectiveness before wider regulatory approval.
Oestrogen receptor-positive breast cancer is a form of the disease that can grow in response to the hormone oestrogen.
Etcamah, whose generic name is camizestrant, was tested in combination with a cyclin-dependent kinase 4/6 inhibitor.
Known as CDK4/6 inhibitors, these medicines block proteins that help cancer cells grow and divide.
AstraZeneca said the Etcamah combination has also been approved in Japan, the UAE and Saudi Arabia based on the Serena-6 trial results.
The company said breast cancer remains the leading cause of cancer death among women in Europe, with more than 140,000 deaths and more than 540,000 patients diagnosed in 2024.
AstraZeneca shares were down 0.6 per cent at 12,628 pence in London on Thursday.
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