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Opinion

Why the growth of gut-tech could transform female health outcomes

By Dr Caitlin Hall, chief dietitian and head of clinical research at myota

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Dr Caitlin Hall

The human digestive system is a complex, fascinating network of organs and tissues.

Home to trillions of bacteria, our gut plays a crucial role in an array of bodily functions beyond the conversion of food to energy – from the balancing of hormones to the prevention of disease.

Recent breakthroughs in our understanding of the function of the human gut have fuelled a significant increase in innovation in the gut health space.

As a result, the market is seeing a rise in ‘gut-tech’: technologies designed to aid or improve the important functions of our gut in order to improve health outcomes.

This is a trend that females can celebrate. At long last, attention commensurate with its significance is being focused on the gut, and this is having a transformative outcome on our understanding of the female experience of health and disease, and on the availability of therapeutics and treatments designed for the female body.

Mapping the growth of gut-tech

The majority of innovation in the gut-tech space is focused on the gut microbiome, a term referring to the trillions of bacteria that exist throughout the gastrointestinal tract, but especially in our large intestine.

Until the turn of the century, very little was known about the function or composition of the microbiome. This all changed following rapid advances in the sophistication and capability of sequencing technologies.

​​In 2007, Human Microbiome Project researchers at the United States National Institutes of Health started exploring the importance of microbiota for health, and in 2020, the European Bioinformatics Institute pooled more than 200,000 gut genomes to create a genetic database of human gut microbes.

By 2021, the extent of information and the consequences of this information for scientific research inspired James Kinross, a microbiome scientist and surgeon at Imperial College London, to name the gut microbiome as “the most important scientific discovery for human healthcare in recent decades.”

Today, we understand in more detail than ever before the mechanisms by which gut bacteria ferment dietary fibre to produce short-chain fatty acids (SCFAs).

These molecules are involved in the immune response, in digestion, in hormone regulation, and in the reversal and prevention of chronic diseases including cancer, depression, IBD and diabetes. It’s not a stretch to claim that nearly every marker of human health – including mental health – is in some way modulated by the activity of the gut.

It follows that technologies designed to aid or alter this activity will have significant health outcomes, explaining the huge growth in the valuation of the human microbiome market.

Currently estimated at a value of US$269 million, this market – of which therapeutics accounts for the majority share – has a compound annual growth rate of 31.1 per cent.

Should gut-tech be considered a subset of femtech?

For a start, we know that many of the chronic health conditions related to the activity of the gut microbiome are conditions that statistically affect women more than men.

These conditions include inflammatory and autoimmune conditions such as arthritis, IBD and IBS, as well as digestive disorders that cause nausea and/or bloating.

Women are also more likely to be affected by depression and other mental health conditions that are thought to be triggered by an imbalance of hormones in the brain – hormones that are directly linked to SCFA production by the microbiome.

Also on account of the hormone/microbiome relationship, researchers now believe that therapeutics targeting the microbiome represent a new frontier in treating menopause symptoms and managing peri- and postmenopausal health.

It follows that we can consider gut-tech to be a cornerstone of fem-tech, as these technologies translate our improved understanding of the gut and the microbiome into improved health outcomes for women.

Further progress in the development of gut-tech for the benefit of female health outcomes will require continued efforts to better understand the function and role of the microbiome, as well as concerted work to improve the geographic and ethnic diversity of microbiome samples used for research purposes.

 

Dr Caitlin Hall is the chief dietitian and head of clinical research at myota, a gut health start-up based in London that uses machine learning, microbiome sequencing and analytical chemistry to explore and promote the therapeutic benefits of a healthy gut microbiome.

News

Listening to pain: What eight women taught me about the state of women’s health in the UK

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By Ruby Raut, founder & CEO, WUKA

It’s Ruby here, founder of WUKA and, like many of you, someone who’s been dismissed, doubted, and left waiting far too long when it comes to menstrual health.

Last week, I spoke at an event hosted by the Menstrual Health Project. It wasn’t just another panel or pitch session; it was a wake-up call.

The room was filled with GPs, pharmacists, educators, innovators, and women who have lived the daily reality of conditions like endometriosis, PCOS, PMDD, and premature ovarian insufficiency.

We weren’t there to celebrate solutions. We were there to listen. And what we heard broke us open.

The Stories Behind the Statistics

I walked out of that room with one page of notes — not data, not theory, but pain in ink.

The stories were raw and repetitive. Women told us of:

  • 14 years of seeking help and getting none.
  • 3 decades of living in pain.
  • Being laughed at for wanting to come off contraception.
  • Being told to “just go on the pill.”
  • Waiting for a laparoscopy since 2015, and still waiting in 2025.
  • Being asked to gain weight to get a period or lose weight to manage PCOS.
  • Being offered pregnancy as a “solution.”
  • Losing jobs because of endometriosis.

This is not an isolated list of frustrations. It’s a mirror reflecting the state of women’s health in the UK today.

Behind every statistic, there’s a woman who has rearranged her life around pain, missed promotions, cancelled plans, and lost trust in her own body.

The System Is Failing Us, and We Know It

Hearing these stories, I couldn’t help but think of it like a leaking roof.

You notice the drip, you report it, but you’re told it’s nothing serious, to just wait it out.

Days turn into months, months into years. By the time someone finally takes a proper look, the ceiling has collapsed.

That’s what living with an untreated women’s health condition feels like, small symptoms dismissed until they become impossible to ignore. That’s what our healthcare system is doing to women.

We don’t have a lack of data, we have a lack of listening.

When women describe pain, the system translates it into exaggeration. When they ask for options, they get the same recycled advice: “Go on the pill.”

The medical model still treats menstruation as a niche, not a vital sign.

And that’s why listening matters. Because until we treat lived experience as evidence, we’ll keep designing systems that ignore reality.

Learning from Lived Experience

As founders, practitioners, and advocates, we often talk about innovation, new tech, better diagnostics, smarter apps. But innovation without empathy is just noise.

Listening to eight women share their stories of endometriosis, PCOS, and PMDD reminded me of something fundamental: we can’t fix what we refuse to feel.

It takes courage to speak about periods, pain, infertility, and loss in a room full of professionals.

Yet these women did, not because they wanted sympathy, but because they wanted change.

Their words carried a collective message: “We don’t need to be fixed, we need to be heard.”

The Change We Need

So, what would change actually look like?

  1. Menstrual health education in medical schools.
    Not as a module, but as a mainstream subject. Every GP, nurse, and specialist should understand menstrual health the way they understand blood pressure.
  2. Inclusive menopause and menstrual support, for all ages, all bodies.
    Menstrual and menopausal health should not be separate conversations. Hormonal health spans a lifetime.
  3. Accessible care at every level.
    Support should start at the local pharmacy, not five years into a diagnosis journey. Pharmacists and primary care teams can be the first line of empathy and intervention.
  4. Private and public health insurance that covers menstrual conditions.
    No woman should have to choose between financial stability and pain management.
  5. Policy change that protects and respects women’s health.
    We need national recognition that menstrual health is not a luxury — it’s a basic human right.

What Listening Really Means

Listening is not passive. It’s radical.

It means staying in the discomfort of someone else’s pain long enough to see the system that caused it. It means asking, not assuming. It means holding space before we offer solutions.

The Menstrual Health Project event reminded me that we can’t rely on numbers alone. Data gives us proof. Stories give us purpose. And when you combine both, that’s when transformation begins.

Why WUKA Cares

At WUKA, we started with period underwear, but what we’re really building is period equity.

Every conversation, campaign, and product we create is rooted in one belief: women deserve better.

Better care. Better education. Better respect.

Because menstrual health is not a side issue. It’s a social justice issue. It’s about the right to live without shame, without silence, and without suffering that’s dismissed as “normal.”

If you’re someone living with any of this, endometriosis, PCOS, PMDD, or anything that makes you feel unseen, I see you. You are not alone. You deserve better, and we will keep fighting for you.

Let’s listen louder. Let’s care deeper. Let’s make menstrual health mainstream.

With you always,

Ruby x

Founder & CEO, WUKA

P.S. Check out the incredible work of the Menstrual Health Project. They’re not just raising awareness, they’re rebuilding the narrative.

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Diagnosis

Why gestational diabetes underdiagnosis is a women’s health crisis

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By James Jackson, CEO at Digostics

Gestational diabetes (GDM) is one of the most under-recognised challenges in maternity care today.

Despite affecting around one in five pregnancies in the UK, GDM remains a blind spot in policy and practice, with devastating consequences for women and their children.

New research continues to expose the scale of the problem.

A recent NIHR-funded study published in Diabetic Medicine found that standard NHS testing methods miss over 50 per cent of cases.

Put simply: thousands of women each year go undiagnosed, untreated, and exposed to avoidable risks.

For a condition we know how to diagnose and manage, this represents a serious failure in women’s healthcare.

The human cost of missed diagnosis

When gestational diabetes is not picked up, the consequences are immediate and long-term.

During pregnancy, women face higher risks of preeclampsia, larger babies, emergency C-sections, and stillbirth. Babies are more likely to need neonatal intensive care due to breathing difficulties or low blood sugar.

The risks don’t end at birth.

Mothers who have had GDM are up to 50 per cent more likely to develop type 2 diabetes within 5–10 years. Their children also face an increased lifetime risk of obesity and diabetes.

These outcomes are not rare, nor are they inevitable. They are the product of a testing system that is not fit for purpose.

An unequal system

Current UK pathways rely on risk-factor–based screening rather than universal testing.

         James Jackson

This already puts women at a disadvantage compared with countries such as Spain, Italy, and many others, where all pregnant women are routinely screened.

But even within this narrower approach, the NHS faces a further problem: in-clinic oral glucose tolerance tests (OGTTs), used to test for GDM, are prone to delays in blood sample processing, leading to false negatives.

Research shows that when samples are processed correctly  diagnoses increase from 9 per cent to 22 per cent — more than double.

The burden of this diagnostic failure falls hardest on women from disadvantaged backgrounds.

Attending early-morning, hospital-based tests is more difficult for women juggling shift work, childcare, or long travel times.

Women from ethnic minority groups, who already face higher rates of maternal complications, are also more likely to be missed. In this way, testing failures are not just a clinical problem but a driver of health inequalities.

The case for innovation

This is where innovation can play a transformative role.

We have seen in other areas of healthcare — from remote monitoring to home blood pressure checks — how new approaches can increase accuracy, improve access, and reduce inequalities.

Gestational diabetes testing should be no different. Technologies such as at-home oral glucose tolerance tests (OGTTs) are designed to meet the same clinical standards as hospital testing, while overcoming the practical barriers of travel, fasting, and sample degradation.

By enabling women to test from home, results can be processed immediately and shared directly with care teams, reducing missed cases and ensuring timely diagnosis.

Early work with NHS Trusts has already shown that this model not only identifies more cases but also improves access for diverse patient groups, including those typically underserved.

From evidence to action

Despite clear data, progress has been slow. Part of the challenge is that more accurate testing uncovers more cases — and more cases mean more workload for already stretched maternity services.

But failing to diagnose does not make the problem go away; it only delays care and worsens outcomes.

In the long run, undiagnosed gestational diabetes costs the NHS more through emergency interventions, neonatal intensive care, later-life type 2 diabetes, and the ongoing workload and cost pressures this creates for primary care.

The evidence is clear. Now it must translate into policy. That means:

  • Recognising underdiagnosis as a patient safety issue on par with other maternity scandals.
  • Guaranteeing that all women offered testing receive accurate, reliable results, rather than being failed by flawed processes.
  • Supporting innovation that improves accuracy and equity, whether in the clinic or at home.
  • Embedding the patient voice in service design, especially from women in disadvantaged and minority communities most affected by current failures.

A call to prioritise women’s health

Gestational diabetes is not a niche concern; it is a mainstream women’s health issue with lifelong consequences.

Every undiagnosed case represents not just a missed number, but a mother at risk of preeclampsia or birth trauma, a baby at risk of intensive care, or a family facing preventable illness later in life.

As maternity services undergo yet another review, it is striking that the diagnostic gap in GDM remains so little discussed.

We cannot claim to be serious about women’s health while ignoring one of the most widespread and preventable sources of harm in pregnancy.

Innovation has a role to play — but innovation must be matched by policy will.

If we are to modernise maternity care, we must start by ensuring that every woman has access to accurate, timely, and equitable testing for gestational diabetes.

Because every mother deserves certainty. And every baby deserves the best start in life.

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Opinion

Understanding inflammaging and how preventative health data could help lessen its impact

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By Dominique Kent, CEO, Bluecrest

As women, we spend much of our lives juggling, I know this from my own experience.

Running a business, raising a family, caring for parents as they get older, the list is endless. Somewhere in the mix, our own health slips down the priority list.

That is why the idea of inflammaging resonates so strongly with me.

It is a quiet, creeping process in the body: low-level inflammation that builds up over time and accelerates ageing.

Unlike a sprained ankle or a winter flu, you cannot feel it happening.

Yet it’s there, silently increasing the risk of conditions that affect so many women in later life such as heart disease, osteoporosis and dementia.

My background before Bluecrest was in the care sector where I saw first-hand what happens when people live longer but not necessarily well.

Too many spent their final years dealing with pain, frailty and loss of independence.

It shaped my belief that the goal for us all should not just be about lifespan but healthspan: the years we live in good health, able to do the things we enjoy and remain independent.

Inflammaging is a direct and silent threat to this, so it’s something that needs to be addressed.

We as women face some particular challenges here. Hormonal changes during menopause remove a natural buffer against inflammation. Autoimmune conditions, which are often inflammatory, are far more common in women.

There are pressures outside of our biologies too, which often fall more heavily on women: stress, trauma, poor sleep, carrying the invisible load of family responsibilities.

All of these add to the inflammatory burden.

The danger is that inflammaging is invisible, you don’t wake up one day and feel it.

Instead it builds, and its impact often only shows when something serious has developed. This is what makes it so risky.

We already know that women’s health issues are often picked up late, misdiagnosed or brushed aside. Add a hidden process like inflammaging into the mix and you see why prevention is so important.

That focus on prevention is what drew me to Bluecrest.

        Dominique Kent

The NHS has made prevention a key part of its long-term plan, and rightly so. If we can spot risks earlier, through small and regular interventions, we can act earlier. That is good for individuals and for the health system.

Inflammaging links directly to so many of the chronic conditions that we see in the headlines, the ones that put the heaviest strain on the NHS, so tackling it at source makes sense.

At Bluecrest, I see how empowering it can be when women come for a health check.

Often it is the first time in years they have put themselves at the top of the list, rather than convincing their husbands or parents to get checked out.

The results are not always perfect, but even when they show areas of concern, women tell me they feel in control.

They leave with a plan, and with knowledge which can be a huge turning point.

I also think about this in the context of business.

Midlife is often when women are at the peak of their careers, yet it is also when health issues start to appear. If hidden risks like inflammaging go unaddressed, we lose women from the workforce at a time when their skills and leadership are most needed.

For me, that’s why prevention is not just a personal issue, it is an economic one.

The good news is that there are things we can do.

A balanced diet, regular exercise, proper sleep and managing stress all help reduce inflammation. Stopping smoking and cutting back on alcohol make a difference too.

But it is unrealistic to leave it all to the individual – and we’ll fail if we add this to an already never-ending list of responsibilities that women take on.

This is where femtech has such a vital role to play.

For too long, women have lacked access to the kind of information that would allow them to make confident and informed health decisions. Now we are seeing new technologies emerge that can change that.

From wearable devices that track sleep and stress, to apps that monitor cycle changes, to biomarker tests that give an early picture of cardiovascular or metabolic risk, women can increasingly access the data they need to understand their own bodies and act sooner.

At Bluecrest, we see how powerful it is when women are given personalised health information alongside the expertise and support to understand it. It shifts prevention from being a vague idea into something tangible.

When data is made accessible, women are more likely to act, whether that is adjusting lifestyle choices, speaking to a GP, or booking follow-up tests.

For femtech to really deliver, though, it has to be part of a bigger ecosystem.

Women need healthcare services that take their concerns seriously, workplaces that respect their health needs, and innovations that are affordable and fit in with their lives.

You’re not going to go and get your inflammation levels checked if you have to take a day off work or caring responsibilities and travel 50 miles to get there.

Data is only empowering when it is clear, trusted and connected to practical next steps.

That is the opportunity now: to combine the science of inflammaging with the growing power of technology, so that women can extend not only lifespan but healthspan, with more years lived in good health and independence.

As a female CEO, I feel a responsibility to use my voice on issues like this.

Women’s health has too often been overlooked, underfunded and under-researched.

Inflammaging may be silent, but it does not have to remain invisible.

By naming it, understanding it, and taking action early, we can give women more years of healthy, independent life.

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