News
We must act to remove the barriers to digital health, say experts
Women’s health experts have called for action to remove the “unacceptable” barriers to digital health.
Digital health technologies have been shown to improve women’s health and promote equity.
A new WHO/Europe report has found that digital health tools are particularly useful in areas related to gynaecology, obstetrics, psychiatry and nutrition, improving access to healthcare services and empowering women to have more autonomy.
However, experts have warned that barriers, such as digital literacy and limited access to technologies, could prevent many girls and women from using these innovations.
“Addressing the barriers to digital health technologies is crucial for ensuring all women benefit equitably,” Dr Eboni January, board-certified physician and surgeon, told Femtech World.
“Ensuring that digital health solutions are user-friendly and available in various languages can significantly enhance accessibility. Additionally, providing low-cost or subsidised devices and internet access can help alleviate financial barriers.”
Developing digital health technologies that are culturally sensitive and relevant to the diverse needs of women is also crucial, said January.
“Engaging with community leaders and stakeholders can help ensure that these technologies are designed with cultural considerations in mind.”
Dr Louise Newson, GP and menopause specialist, said community-based digital education initiatives could help women develop the skills needed to navigate and utilise digital health tools effectively.
“Working with tech companies and policymakers is also essential to ensure that affordable devices and internet access are available to all, particularly in underserved communities,” she explained.

Dr Louise Newson, GP and menopause specialist
Women and girls are 25 per cent less likely than men to have sufficient knowledge and digital skills to use technology. Digital health disparities disproportionately affect marginalised women, making it challenging for them to access healthcare services.
Dr Emilia Pasiah, board-certified physician specialised in family medicine, said digital literacy programmes are essential.
“Educating women on how to use digital health tools effectively can empower them to take control of their health,” she told Femtech World.
“Healthcare providers must be trained to incorporate digital tools into their practice and advocate their use among patients. This can enhance trust and promote the benefits of digital health solutions.
“Addressing privacy and security concerns is also crucial to gaining trust. Ensuring robust data protection and transparency about how data is used can alleviate fears and encourage the adoption of digital health tools.”
This privacy aspect might be particularly crucial in regions or communities with stigma or social barriers.
Melissa Snover, founder and CEO of Nourished, added: “We need to provide education and resources to boost women’s digital skills, and make these technologies accessible to everyone, regardless of their socioeconomic background. This means developing affordable solutions and implementing supportive policies tailored to the unique needs of underserved communities.”
When considering health outcomes for women facing socioeconomic barriers, Annie Thériault, managing partner at Cross-Border Impact Ventures, said it is “critical” that we recognise these groups would only take up interventions that are heavily subsidised or free.
“Public healthcare systems and insurance providers have a role to play in addressing barriers to digital health solutions and should implement mechanisms to make digital health services affordable and reimbursable,” she said.
“Leveraging the capacity and ubiquity of private sector players can also significantly impact digital health uptake. Hardware manufacturers have a tremendous opportunity to drive traffic to their storefronts by partnering with public health entities that could promote their solutions and provide digital health training in-store.”
Companies like Apple, Thériault said, are already providing digital literacy sessions in-store, though this is largely unknown.
Some, however, believe the barriers to digital health adoption should be addressed early on.
According to Theresa Neil, founder and CEO of Guidea, creating accessible and equitable digital health solutions should start with culturally competent research.
“Culturally competent research means planning and executing research studies to include women of all abilities, literacy levels, access to technology, and caregiving responsibilities.
“Early market and UX research could identify opportunities where technology can improve patient outcomes, and where technology may be just one piece of a broader solution.”
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Diagnosis
Lung cancer drug shows breast cancer potential
Ovarian cancer cells quickly activate survival responses after PARP inhibitor treatment, and a lung cancer drug could help block this, research suggests.
PARP inhibitors are a common treatment for ovarian cancer, particularly in tumours with faulty DNA repair. They stop cancer cells fixing DNA damage, which leads to cell death, but many tumours later stop responding.
Researchers identified a way cancer cells may survive PARP inhibitor treatment from the outset, pointing to a potential way to block that response. A Mayo Clinic team found ovarian cancer cells rapidly switch on a pro-survival programme after exposure to PARP inhibitors. A key driver is FRA1, a transcription factor (a protein that turns genes on and off) that helps cancer cells adapt and avoid death.
The team then tested whether brigatinib, a drug approved for certain lung cancers, could block this response and boost the effect of PARP inhibitors. Brigatinib was chosen because it inhibits multiple signalling pathways involved in cancer cell survival.
In laboratory studies, combining brigatinib with a PARP inhibitor was more effective than either treatment alone. Notably, the effect was seen in cancer cells but not normal cells, suggesting a more targeted approach.
Brigatinib also appeared to act in an unexpected way. Rather than working through the usual DNA repair routes, it shut down two signalling molecules, FAK and EPHA2, that aggressive ovarian cancer cells rely on. FAK and EPHA2 are proteins that relay survival signals inside cells. Blocking both at once weakened the cells’ ability to adapt and resist treatment, making them more vulnerable to PARP inhibitors.
Tumours with higher levels of FAK and EPHA2 responded better to the drug combination. Other data link high levels of these molecules to more aggressive disease, pointing to potential benefit in harder-to-treat cases.
Arun Kanakkanthara, an oncology investigator at Mayo Clinic and a senior author of the study, said: “This work shows that drug resistance does not always emerge slowly over time; cancer cells can activate survival programmes very early after treatment begins.”
John Weroha, a medical oncologist at Mayo Clinic and a senior author of the study, said: “From a clinical perspective, resistance remains one of the biggest challenges in treating ovarian cancer. By combining mechanistic insights from Dr Kanakkanthara’s laboratory with my clinical experience, this preclinical work supports the strategy of targeting resistance early, before it has a chance to take hold. This strategy could improve patient outcomes.”
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