Mental health
Commission to tackle long-neglected field of women’s mental health

A UK researcher is to co-lead a new Lancet Psychiatry Commission on Women’s Mental Health.
This is the first global initiative to systematically connect biology, social context and clinical care for women’s mental health across their entire life course, and to translate that knowledge into actionable change, using precision psychiatry as its central framework.
It will bring together clinicians, researchers, policymakers and women with lived experience as equal partners.
The Commission aims to establish a new, evidence-based standard for women-centred mental health care that reflects both scientific progress and the realities of women’s lives, with targeted recommendations for clinicians, researchers, policymakers and medical educators.
Women’s experiences will be highlighted through public engagement on the MIAMENTAL website.
Dr Marisa Casanova Dias, consultant perinatal psychiatrist and senior lecturer in women’s mental health at King’s College London is co-leading the project with Livia De Picker, professor of immunopsychiatry at the University of Antwerp.
The King’s researcher said: “The Commission will mobilise policy change, translate evidence into accessible narratives, and personalise what often can seem like abstract statistics.
“Women’s mental health must be understood as a fundamental human right across the life course, and we all stand to gain from its prioritisation and improvement.”
Women’s health has been historically under-researched.
Despite bearing a disproportionate burden of common mental disorders, women remain under-represented in clinical trials, sex-disaggregated analyses are inconsistent, and differences in pharmacokinetics, hormonal changes and treatment response are rarely integrated into practice.
Adverse consequences, which are increasingly recognised, include women’s pain and psychological distress being dismissed or normalised, resulting in delayed diagnosis, poor healthcare and worse outcomes.
Women carry a disproportionate burden of mental health disorders.
They live longer than men, yet spend more years in poor health, with a large share of years lived with disability attributable to mental disorders.
Globally, women are around 1.5 to 2 times more likely than men to experience depression and anxiety, and an estimated one in four women will face a mental disorder in her lifetime.
These heightened mental health risks cluster largely around key biological and social transitions, namely puberty, the perinatal period, menopause and older age, and are compounded by knowledge and resource gaps in mental health care.
Current psychiatric frameworks, education and guidelines remain poorly aligned with the realities of women’s bodies and lives.
Recognising the importance of every stage of life, the Commission will adopt a lifespan approach organised around six key stages: prenatal and early development, pre-puberty childhood, adolescence, adult reproductive years, midlife and older age.
At each stage, the Commission will emphasise how biology, context and care interact over time, rather than treating these domains in isolation.
Mental health
Dr-Julian helps deliver breakthrough mental health support for Black and ethnically minoritised mothers

A groundbreaking digital perinatal mental health pilot for Black and ethnically minoritised women has helped women access support faster, complete therapy at higher rates, and recover more successfully than national averages.
The partnership between digital tech company Dr-Julian and The Essential Baby Company Ltd within a new model of mental health care named haPPIE SHE Cares – who offer personalised support for women sharing their healthcare experiences, showed results well above NHS benchmarks for Black and ethnically minoritised women.
The pilot was created to help women who are less likely to use traditional mental health services during pregnancy and in the first year after giving birth.
By combining trusted community referrals, culturally aware support, and fast access to therapy through Dr-Julian’s online and virtual care platform, the programme delivered standout results.
Every woman who joined the pilot started therapy, 90 per cent completed treatment, and 74 per cent recovered; well above the NHS benchmark of around 52 per cent.
Women referred through community organisations accessed support in just one day on average, compared with around 21 days through many standard services.
Even the programme’s regular referral route reduced waits to 13 days.
The findings come as NHS leaders continue to focus on maternity inequalities and unequal access to mental health care.
Black and ethnically minoritised women can face barriers including stigma, language needs, lack of trust in services, childcare pressures, and difficulty navigating complex systems.
The haPPIE SHE Cares model was designed to break down those barriers by working with trusted community groups, offering culturally informed support, and where possible matching women with therapists who understood their background or language.
Gemma Poole for The Essential Baby Company said: “Too many women who need help feel unseen, unheard or unable to get support when they need it most.
“This project shows that when services are built around trust, culture and community, women engage, recover and thrive.
“This early success could provide a blueprint for reducing inequalities in maternal mental health care across the UK. Behind every statistic is a mother who felt supported, a family that benefited and a woman who found her voice.
“Mental healthcare must work for every community. This partnership shows that when high-quality therapy is combined with culturally responsive support, outcomes improve and women get help faster.
We are proud to have provided the therapists, virtual care systems and digital pathways behind this programme. We believe this model could help NHS organisations nationwide cut waiting times and improve recovery rates.”
Women who took part described the programme as life-changing, saying it reduced isolation, gave them confidence speaking with healthcare professionals, and made them more willing to seek help.
With growing pressure on maternity and mental health services, leaders behind the project say the pilot offers a practical solution that improves care while helping cut long waiting lists.
Plans are now being explored to expand the model through training, regional partnerships, and future funding.
Mental health
Poor sleep linked to Alzheimer’s risk in older women – study

Poor sleep may signal higher Alzheimer’s risk in older women with greater genetic risk, a study suggests.
Older women who reported poorer sleep also showed greater memory difficulties and more Alzheimer’s-related brain changes, the study found.
That pattern appeared only in women with higher genetic risk, suggesting sleep complaints may be a stronger warning sign for some women than for others.
Researchers examined 69 women aged 65 years and older taking part in the Women Inflammation Tau Study, an ongoing project focused on ageing and Alzheimer’s disease risk.
Participants completed questionnaires about their sleep quality, underwent memory testing and received brain scans measuring tau. Tau is a protein that accumulates abnormally in Alzheimer’s disease.
The study found that poorer self-reported sleep was associated with worse visual memory performance and greater tau accumulation in brain regions affected early in Alzheimer’s disease, but only among women with higher genetic risk.
Women with lower genetic risk did not show the same relationship between sleep complaints, memory and tau build-up. The finding was specific to visual memory and was not observed for verbal memory.
Researchers said the results add to growing evidence that sleep disturbances and Alzheimer’s disease may reinforce one another over time.
Previous studies have suggested that disrupted sleep can contribute to the build-up of abnormal tau proteins, while Alzheimer’s-related brain changes may also interfere with healthy sleep patterns.
Because women account for nearly two thirds of Alzheimer’s cases and frequently report poorer sleep quality than men, the researchers said sleep may represent an important and potentially modifiable risk factor in older women.
The authors noted that self-reported sleep assessments are inexpensive and easy to administer, raising the possibility that sleep complaints could help identify people who may benefit from closer monitoring or early intervention.
They also suggested that improving sleep could become a target for future Alzheimer’s prevention strategies, particularly for women at elevated genetic risk.
Mental health
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