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International consortium launches US$1m AI grant to tackle ovarian cancer

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An international group of ovarian cancer research charities has launched a new AI-focused grant aimed at accelerating progress in one of the most underfunded and least survivable cancers affecting women worldwide.

The Global Ovarian Cancer Research Consortium — a collaboration between organisations in the US, UK, Canada and Australia — has announced a US$1m AI Accelerator Grant to support research into ovarian cancer, alongside US$1m in computing credits from Microsoft’s AI for Good Lab.

Each year, approximately 324,000 women globally are diagnosed with ovarian cancer, and 207,000 die from the disease. Despite ongoing efforts, survival rates have improved little over the past decades. The consortium’s grant aims to stimulate innovation using artificial intelligence to improve detection, diagnosis and treatment outcomes.

The consortium includes Ovarian Cancer Research Alliance (US), Ovarian Cancer Action (UK), Ovarian Cancer Canada, and the Ovarian Cancer Research Foundation (Australia). It was established in 2024 to coordinate international efforts and pool resources in an effort to drive faster progress.

“For far too long, survival rates have barely budged, and women around the world continue to face devastating odds,” said Audra Moran, president and CEO of Ovarian Cancer Research Alliance (OCRA). “We cannot afford to wait another decade for meaningful progress. At OCRA, we believe that artificial intelligence could hold the key to accelerating the breakthroughs we so desperately need — from earlier detection to better treatment options — which is why we envisioned a grant of this global magnitude and scope specifically for AI.”

The grant will require research teams to include members from all four participating countries. Successful applicants will receive Azure cloud computing resources through Microsoft’s AI for Good Lab, intended to scale the impact of their research.

“New discoveries are needed to find lifesaving treatments for ovarian cancer, a cancer that tragically still has a low survival rate,” said Juan Lavista Ferres, chief data scientist and director of Microsoft’s AI for Good Lab. “Equipping leading researchers around the globe with powerful AI tools and computing resources will help accelerate their critical work, hopefully leading to breakthroughs that save women’s lives.”

Global projections suggest that by 2050, diagnoses of ovarian cancer will rise by over 55%, with an estimated 503,448 women affected annually. Deaths are expected to reach 350,956 per year. While AI is already being applied across a range of cancers, its potential impact in ovarian cancer remains underexplored.

See more about the grant programme here : https://ocrahope.org/research/information-for-researchers/grant-programs/

Insight

Women’s mental health happens between appointments

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By Ritika Sukhani – Psychologist, part of Véa’s Clinical Advisory Board

Women’s mental health often unfolds before, between and around appointments, long before it can be neatly explained in one conversation.

A woman arrives at a GP appointment with six months of feeling “off” behind her. Not acutely unwell. Not necessarily in crisis. Just not herself.

Poor sleep. Brain fog. Lower tolerance. Irritability before her period. Anxiety before meetings. A sense that her cycle, workload, relationships and energy are interacting – but not in a way she can neatly explain when the appointment begins.

She has tracked symptoms, Googled at midnight, screenshotted articles, made notes in her phone and tried to remember what changed, when it changed and what might have triggered it.

But when she finally gets the chance to talk, the task is not only to describe how she feels. It is to organise months of fluctuating experience into a story clear enough to communicate.

This is one of the most overlooked forms of labour in women’s mental health: not simply experiencing distress but having to make it coherent.

In the NHS, women’s mental health rarely arrives through one door. It may appear in primary care as exhaustion, poor sleep or “not feeling like myself”.

It may appear in NHS Talking Therapies as anxiety or low mood. It may sit beneath a menopause conversation, a fertility journey, chronic pain, trauma, caring responsibilities, burnout or the quiet work of holding everyone else together.

The NHS provides essential care.

NHS Talking Therapies received 1.81 million referrals in 2024/25, with 1.21 million referrals accessing services and 50.5 per cent of referrals moving to recovery after completing treatment.

But women’s lives do not unfold in pathway-shaped ways.

Their distress is often cumulative, contextual and relational. It is shaped not only by symptoms but by the conditions around those symptoms: work, debt, trauma, hormones, caregiving, discrimination, physical health, relationships, sleep and the pressure to keep functioning.

That is why women’s mental health needs more than access to services.

It needs continuity.

The work before the appointment

Women are often encouraged to advocate for themselves in healthcare. At its best, this is empowering. It supports agency, preparation and active participation in care.

But self-advocacy can also become another unpaid job.

It requires women to notice what is happening, remember when it started, connect it to context, decide what feels relevant, find the right words and communicate it clearly – often while already tired, anxious, in pain or emotionally overwhelmed.

In clinical care, distress is often the beginning of an assessment. Clinicians are trained to explore duration, severity, functioning, risk, context, history and meaning.

That process matters. It is how distress becomes understood with care.

The issue is broader than any single consultation.

Women’s mental health experiences often unfold over weeks, months and years, while healthcare conversations may happen in short, pressured windows.

Patterns form outside the appointment room: between cycle phases, work demands, caring responsibilities, relational stress, poor sleep and moments of emotional overload.

The UK Government’s Women’s Health Strategy survey found that 84 per cent of respondents said there had been times when they, or the woman they had in mind, were not listened to by healthcare professionals.

It points to something structural: the difficulty of making complex, fluctuating and context-dependent experiences legible inside systems that are often fragmented, time-limited and under pressure.

Endometriosis shows why continuity, language and recognition matter.

Research has found that delays in diagnosis can occur at both patient and medical levels, including when symptoms are normalised by women themselves and by doctors.

For many women, receiving a diagnosis did more than name pain; it provided language, reassurance and possible management strategies.

This is the point we should pay attention to.

Women do not always lack information. Often, they have fragments of it.

The challenge is how to preserve context, recognise recurrence and bring scattered experiences into a form that supports reflection, communication and earlier action.

Tracking captures moments. Continuity reveals patterns

We have made enormous progress in helping women track their bodies.

We can now log cycles, sleep, mood, fertility windows, temperature, symptoms, recovery and heart rate variability with increasing precision. Period-tracking apps, for example, have been described as  tools that can support body awareness and menstrual health literacy, while also introducing new forms of work, distress and privacy concern for some users.

That tension matters.

Tracking can help women notice what is happening. But noticing is not the same as understanding. And understanding is not the same as being able to explain.

A cycle tracker can show when a period started. A wearable can show disrupted sleep. A symptom log can hold isolated data points. A notes app can capture fragments of a difficult week.

But unless those pieces are brought together, the interpretive work still falls to the woman.

She is left asking: Is this hormonal? Is this stress? Is this burnout? Is this anxiety? Is this normal for me? Is this pattern important? Should I mention it? How do I explain it?

This is where the first wave begins to meet its limits.

The first wave helped women capture signals.

The next wave could help women interpret context.

The promise of patient-generated health data has always been that it could bridge the gap between everyday life and formal care. But reviews continue to highlight challenges around integration with electronic health records, trust, provenance, data quality and contextual information.

That matters because women’s health data does not become useful simply because it is collected. It becomes useful when it is contextualised.

A poor night’s sleep means something different after one stressful day than after six weeks of overextension.

A low mood entry means something different when it appears in isolation than when it appears repeatedly around a cycle phase, a work pattern or a relationship dynamic.

A spike in anxiety means something different when it is viewed alongside workload, recovery, conflict, hormonal change or self-critical thinking.

The value is not in turning every experience into a metric.

The value is in seeing what repeats, how it repeats and what else is happening around it.

Women’s mental health is systemic

The latest Adult Psychiatric Morbidity Survey found that one in five adults in England had a common mental health condition, with prevalence higher in women at 24.2 per cent compared with 15.4 per cent in men.

It also found a clear socioeconomic gradient, with common mental health conditions more prevalent in the most deprived areas and among people with problem debt.

These figures matter because they remind us that women’s mental health cannot be understood only at the level of individual coping.

Of course, individual support matters. Therapy matters. Medication may matter. Assessment, formulation, risk management and diagnosis all have their place.

But a systemic lens asks what else is happening around the woman.

Who is she caring for? What is she carrying at work? What has she had to normalise? What physical symptoms have been separated from her emotional life? What inequalities shape how quickly she is heard, referred or supported? What happens while she is waiting?

Women’s mental health is often partly biological, partly psychological, partly relational, partly occupational and partly social.

It may not fit neatly into one symptom box at first. It may need time, pattern and context before it becomes clear what kind of support is needed.

This is why the missing layer is not more monitoring – it is supported sense-making.

The need for supported sense-making

Supported sense-making means moving beyond isolated logs and dashboards towards tools that help women understand how different parts of their lives interact over time: body, mood, cycle, stress, relationships, work, recovery and self-talk.

It also means being clear about what technology should and should not do.

Technology should not replace clinical assessment. It should not diagnose from a journal entry.

It should not turn ordinary emotion into pathology or place yet another responsibility on women to optimise themselves.

At its best, it can support the wider ecosystem around care.

It can help women hold onto context before an appointment.

It can help them notice patterns while they are waiting. It can support reflection between sessions. It can help them arrive at conversations with more continuity, while respecting the clinical judgement, formulation and relational care that services provide.

This is where platforms like Véa point toward a thoughtful role for women’s health technology.

By treating reflection, emotion and language as part of women’s longitudinal health context, Véa supports the kind of pattern recognition that often gets lost in daily life. Through micro-check-ins, journalling and reflective prompts, it helps women notice shifts in their internal state over time – not to self-diagnose but to build a clearer relationship with their own patterns.

For some women, that may support a better conversation with a clinician.

For others, it may help them recognise early signs of burnout, understand cyclical changes or notice when work, relationships and recovery are interacting in ways they had not previously named.

At its best, this kind of technology reduced the burden of self-interpretation. It helps women hold onto the thread.

From more data to better continuity

The women’s health gap is often discussed as a research gap, a funding gap and a diagnostic gap.

It is all of those things. McKinsey Health Institute and the World Economic Forum estimate that closing the women’s health gap could add at least $1 trillion annually to the global economy by 2040.6

But there is another gap sitting underneath the others.

A continuity gap.

Women’s mental health experiences are often long, fluctuating and context-dependent. Healthcare systems often encounter them in snapshots. Workplaces may only notice them when performance drops. Women themselves may only recognise the pattern once they are already exhausted.

That gap between lived experience and later explanation is where too much meaning gets lost.

The next generation of women’s health technology should help preserve the story behind the symptom.

It should make room for emotional, cognitive, hormonal and social context without collapsing everything into diagnosis or optimisation. It should support better conversations without pretending to replace clinical care.

Women should not have to rely on memory alone to make sense of months of fluctuating emotional, cognitive and physical experience.

The future of women’s mental health will not be built by asking women to monitor themselves more closely.

It will be built by helping them understand themselves sooner – and arrive at conversations about their health with more continuity, context and clarity.

Learn more about Véa at veajournal.app

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Cancer

Life-prolonging ovarian cancer drug approved for use in England

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A new ovarian cancer drug has been approved for NHS use in England, offering hundreds of women with hard-to-treat disease a life-prolonging treatment.

Elahere is the first new drug for chemotherapy-resistant ovarian cancer to be approved by the NHS for more than 20 years.

Ovarian cancer is the 18th most common type of cancer globally, affecting more than 300,000 women a year.

More than three-quarters of patients are diagnosed at an advanced stage, making the disease harder to treat.

Prof Ruth Plummer, national clinical lead for cancer drugs at NHS England, said: “This represents the most significant breakthrough in NHS treatment for these hard-to-treat ovarian cancers in over two decades – and we’re delighted it will now offer hundreds of women much-needed hope of precious extra time with their loved ones.”

Standard treatment for ovarian cancer usually involves surgery and chemotherapy, but about 80 per cent of patients with advanced disease relapse and most eventually develop resistance to chemotherapy.

According to the National Institute for Health and Care Excellence, patients with folate receptor-alpha-positive platinum-resistant epithelial cancers have until now had limited options when their tumours stop responding to standard chemotherapy.

Now NICE has approved mirvetuximab soravtansine, also known as Elahere, for patients with epithelial ovarian, peritoneal or fallopian tube cancer that has become resistant to platinum-based chemotherapy and whose tumours contain the FRα protein that the drug targets.

FRα is a protein found on the surface of some cancer cells.

NHS England said up to 400 women a year in England could benefit, in what it described as a major milestone for treatment.

Mirvetuximab soravtansine is given through a drip once every three weeks.

A global clinical trial involving eight NHS hospitals found that the treatment delayed cancer progression and prolonged survival by an average of four months, compared with chemotherapy alone, with more manageable side-effects.

Cancer progression means the disease is growing, spreading or worsening.

In 37 per cent of patients, tumours shrank by at least 30 per cent, compared with 16 per cent of those given chemotherapy.

The drug, made by AbbVie, combines a “homing” antibody, which seeks out the FRα protein on the surface of cancer cells, with a cancer-killing molecule that destroys the cell from within.

Experts said the decision was a seminal moment and could significantly improve the quality of life of affected patients.

Rachel Downing, head of policy and external affairs at Target Ovarian Cancer, said: “This is a hugely important moment for women with platinum-resistant ovarian cancer and their families, who have faced limited effective treatment options for far too long. Today’s announcement offers real hope of improved quality of life.”

Victoria Clare, chief executive of the charity Ovacome, said: “Today marks a landmark moment. Being told that platinum-based chemotherapy is no longer working can bring anxiety and uncertainty, particularly when the disease is at an advanced stage, where time and options are limited.

“This recommendation is the first in over 20 years to offer the ovarian cancer community an additional choice at a critical stage, with the potential to make a real difference to patients and their families.”

Helen Knight, director of medicines evaluation at NICE, said: “We heard clearly from patients and clinicians about the very limited options available at this stage of the disease and the substantial burden that chemotherapy places on women’s lives.

“We are pleased that, following a robust process and a new commercial arrangement with AbbVie, we are now able to recommend this treatment for NHS use.”

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Wellness

Being female not a universal stroke risk factor for patients with AF, study finds

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Female sex may not raise stroke risk across all atrial fibrillation (AF) patients, with higher risk mainly seen in women aged 75 and older, a study suggests.

Researchers said stroke prevention for women with the condition should be more personalised, especially for patients under 75.

Dr Amitabh C Pandey, director of cardiovascular translational research at Tulane University School of Medicine, said: “For years, female sex has been included as a risk factor along with other factors such as high blood pressure and diabetes, meaning women were more likely to be prescribed anticoagulants.

“Our study shows younger women may not have as much added stroke risk as previously thought, while older women, particularly those over 75, appear to have a higher risk that deserves close attention.”

The new Tulane University study challenges a long-standing assumption in heart care that being female automatically increases stroke risk for patients with atrial fibrillation.

Atrial fibrillation, often called AF, is a common heart rhythm disorder that causes the heart to beat irregularly.

It is associated with a higher risk of stroke and is often treated with anticoagulants, also known as blood thinners.

The study found that stroke risk did not increase equally across all female patients with AF.

Instead, researchers said being female may act more as a risk modifier, with increased stroke risk seen primarily among women aged 75 and older or those with a greater burden of other health conditions.

Clinicians often use a scoring system to decide whether people with AF should be prescribed blood thinners.

The system gives points for factors including age, heart failure, diabetes, previous stroke, vascular disease and high blood pressure.

Women also receive one point for sex alone.

Researchers said this can mean women with AF become eligible for blood thinners earlier or more often than men with otherwise similar risk profiles.

While blood thinners can help prevent clot-related strokes, they can also increase the risk of bruising, prolonged bleeding, gastrointestinal bleeding and other serious complications.

The researchers analysed approximately 950,000 patients with AF using TriNetX, a large anonymised electronic health record database.

They compared stroke outcomes between male and female patients across three age groups: younger than 65, 65 to 74, and 75 and older.

Male and female patients were matched based on age, other health problems and whether they had been prescribed anticoagulation medicine.

Among patients younger than 75, the study found no significant difference in one-year stroke risk between men and women.

However, among patients aged 75 and older, women had a modest but statistically significant increase in stroke risk compared with men.

In patients aged 75 and older with no additional risk factors beyond age, women had about one additional stroke per 629 patients compared with their male counterparts.

The findings support growing interest in a newer AF risk score, known as CHA2DS2-VA, which removes sex as a standalone risk factor.

However, researchers said more studies are needed and medical guidance remains inconsistent.

Han Feng, assistant professor at Tulane University School of Medicine, said: “This general approach came from women being underrepresented in AFib trials and studies comprising only about one-third of study populations.

“Our study shows not all women with AFib have the same risk profile, and these decisions should be individualised.

Pandey said: “These findings highlight the need for modern tools and approaches that can personalise risk profiles to individuals.

“The goal is not to undertreat patients who need stroke prevention, but to better identify who is most likely to benefit from anticoagulation and who may be exposed to unnecessary risk.”

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