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Hera Biotech raises US$1.9m seed round for endometriosis diagnostic test

Endometriosis affects roughly 190 million women of reproductive age globally

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The medical start-up, Hera Biotech, has closed a US$1.9m seed round to support the commercialisation strategy of its non-surgical diagnostic test for endometriosis.

The funds will be used to complete an in-patient human clinical study, expand the company’s IP portfolio, and support a regulatory pathway with the US FDA.

MetriDx is thought to be the world’s first non-surgical test for definitive diagnosis and staging of endometriosis.

A sample of the patient’s endometrium is collected during an in-office procedure – similar to a pap smear but in the uterus – eliminating the need for surgery. The configuration of the test uses micro-fluidic analysis of single cells obtained from the patient to diagnose and stage endometriosis.

The San Antonio-based start-up hopes MetriDx will bring unprecedented diagnostic capability to physicians, lower liability risk within hospitals, eliminate unnecessary surgical procedures, and reduce the considerable time patients suffer before receiving a diagnosis, while maintaining tissue collection and a direct pathology diagnosis.

Investors in the US$1.9m-round included primarily female supporters from individual sources and investment firms Coyote Ventures, Stella Angels, Althea Group Ventures, and the Kendra Scott Women’s Entrepreneurial Leadership Institute (KS WELI)

Hera intends to start a Series A raise of US$15m in late 2022 to support the commercial launch of its product in 2024.

“Our seed round was oversubscribed by nearly 100 per cent from our original goal – which is an enthusiastic validation of our technology and the need for a solution for this pervasive and persistent, yet unsolved problem, in women’s health,” said founder and CEO, Somer Baburek, MBA.

Lesley Robinson, director of the KS WELI, said: “The Kendra Scott Women’s Entrepreneurial Leadership Institute at the University of Texas is thrilled to be part of Hera Biotech’s successful seed round through their wins at our Fall 2021 Female Founder Pitch Competition and Spring 2022 Dream to Venture events.

“We are dedicated to supporting empowered women with the entrepreneurial spirit that can change the world, and Hera’s mission shines an important light on women’s health.”

Endometriosis, a disease where tissue similar to the lining of the uterus grows outside the uterus, causing pain and infertility problems, affects roughly 190 million women of reproductive age globally.

Wellness

The science behind the scar: What’s really in our period products

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By Ruby Raut, founder and CEO, WUKA

Over the past year, headlines about “toxic period products” have been hard to ignore. Stories about PFAS, heavy metals, and hormone disruptors in pads, tampons, and underwear have sparked global concern, and for good reason. But behind the fear, there’s a scientific story worth understanding.

At the recent House of Lords event, “Have We Reached the Tipping Point for Toxic Period Products?”, researchers and policymakers came together to separate fact from panic. The truth is more nuanced: yes, chemicals and metals are present in some menstrual products, but understanding how much, where they come from, and what that means for our health is key to driving change that’s informed, not sensational.

What Scientists Have Found So Far

Dr Kathrin Schilling, an environmental health scientist at Columbia University, shared new research that tested 16 metals in menstrual products, including arsenic, cadmium, lead, and antimony, all known toxic substances linked to long-term health effects such as cardiovascular disease, kidney problems, and hormonal disruption.

The findings were striking:

  • Non-organic products showed higher levels of lead and cadmium than organic ones.
  • Some reusable and single-use products exceeded 30,000 nanograms per gram (ng/g) of antimony, a toxic metal commonly used in plastics manufacturing.
  • Lead levels varied dramatically, some products contained 100× more than others.

To put this in perspective, even very small doses of lead can cause harm. The World Health Organization confirms there is no safe level of lead exposure. Chronic, low-level contact can gradually affect the nervous system and fertility. The same applies to arsenic, where countries have tightened drinking water limits from 10 µg/L to as low as 1 µg/L after learning that long-term exposure causes disease.

So while the numbers in menstrual products might sound tiny, what matters most is frequency and route of exposure. Menstrual products are used regularly and in contact with one of the body’s most absorbent tissues — the vaginal wall — where absorption is estimated to be 10–80× higher than through skin. Over decades of use, even low concentrations can add up.

Understanding PFAS — The “Forever Chemicals”

Alongside metals, PFAS (per- and polyfluoroalkyl substances) have become another major concern. These synthetic compounds are used for absorbency and stain resistance — but they don’t break down easily, earning the name “forever chemicals.”

They accumulate in soil, water, and the human body, and have been linked to reproductive issues, thyroid disease, and immune dysfunction. California recently became the first state to ban PFAS in menstrual products, while New York is pushing for broader restrictions that include heavy metals and hormone disruptors.

These international shifts signal a clear message: the world is moving towards stricter, transparency-first regulation — something the UK could soon follow.

Why It Matters for Our Bodies

It’s important to remember that our world is already filled with background exposure, from air pollution, processed food, and household plastics. We all live in a chemically complex environment. The key isn’t to fear every product but to understand which exposures matter most and how to minimise them.

Menstrual products are unique because of their intimate and repeated contact with the body. Even trace chemicals can bypass the body’s natural detox systems when absorbed vaginally. This doesn’t mean every product is dangerous, but it underscores why regular, independent testing and clear ingredient disclosure are essential.

Internal vs. External Exposure:  Why It Makes a Difference

One of the least understood parts of this debate is the difference between internal and external products. A pad or period underwear sits on the skin; it can only transfer chemicals through surface contact. But products like tampons or menstrual cups are inserted directly into the vagina, an environment that absorbs substances 10–80 times more efficiently than normal skin.

That’s because the vaginal wall is highly vascular, full of small blood vessels, and it bypasses the liver, the organ that usually filters and detoxifies harmful substances. So when a chemical is absorbed vaginally, it goes straight into the bloodstream.

Yet, most testing and regulation still treat all menstrual products as if exposure happens through skin contact. There’s very little research separating the risk profiles of internal (tampons, cups, discs) versus external (pads, underwear) products. That’s why scientists like Dr Schilling emphasised the need for new safety standards that actually reflect how the body interacts with these materials, not just how a fabric performs in a laboratory test.

How Responsible Brands Are Responding

Some brands are already ahead of regulation.

At WUKA, we take this responsibility seriously. We are one of the very few period underwear brands with no PFAS detected in our products. Every batch is tested rigorously, both at source (in China) and again in the UK by Eurofins laboratories, an independent global testing agency.

We also screen for toxic chemicals, metals, and harmful finishes, ensuring that what touches your body is as safe as it is sustainable. As a founder, I always remind our team: I use our products myself. If I wouldn’t wear it, I wouldn’t make it for anyone else.

Our philosophy is simple,  transparency builds trust. Consumers shouldn’t need a chemistry degree to choose a safe period product.

The Path Ahead

The science is clear: menstrual product safety deserves the same rigour as drinking water, cosmetics, or food. But we can also take heart, awareness is growing, data is expanding, and governments are beginning to act.

As policymakers push for international standards (through bodies like the ISO TC338 on menstrual products), and as responsible brands lead by example, the future of menstrual care looks safer, smarter, and far more transparent than the past.

This isn’t just about fear of toxins, it’s about empowering everyone who menstruates with knowledge and choice. Because understanding the science is the first step toward changing it.

Find out more about WUKA at wuka.co.uk

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Features

New research centre aims to tackle gender health gap

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Wales has opened its first women’s health research centre, backed by £3m to tackle health inequalities through research and innovation.

The centre, led by Women’s Health Research Wales, marks the first anniversary of the Women’s Health Plan for Wales, published in December 2024.

First minister Eluned Morgan and minister for mental health and wellbeing Sarah Murphy visited staff, researchers and collaborating communities at the launch.

The work covers prevention, early-onset conditions, rare diseases and care for under-served communities.

The centre brings together researchers, NHS partners, industry, policy makers and communities to develop more effective treatments and ensure services meet women’s needs throughout their lives.

It is designed to strengthen investment in women’s health research, including representation in clinical trials.

Morgan said: “I am passionate about improving women’s healthcare.

“To do that, we must invest in research to gather the evidence we need.

Morgan added: “I am delighted to see how the Welsh Government’s £3m investment, through Health and Care Research Wales, is supporting research based on the experiences of women.

“This will result in better care and better health outcomes for women.”

Projects in development include exploring symptom reporting tools to help manage conditions such as diabetes, heart failure and chronic obstructive pulmonary disease.

Researchers are also investigating how chemicals in menstrual products might affect health, ways to help young people stay active during periods, and pathways to prevent people with polycystic ovary syndrome developing conditions like diabetes and heart disease later in life.

Other projects are exploring fertility issues, including a decision-making tool for women with kidney disease considering whether to have children.

One project is working with women undergoing fertility treatment, investigating why this can lead to mental health issues such as PTSD (post-traumatic stress disorder), with the aim of creating guidance for trauma-informed fertility care.

Morgan said: “This innovative new research centre is a key part of the Women’s Health Plan and will help us better understand women’s experiences.

“It will lead to more effective treatments and make sure that our health service delivers improved outcomes for women in Wales.”

Debbie Shaffer is founder and director of Fair Treatment for the Women of Wales and chair of Women’s Health Wales Coalition.

Shaffer said: “Research into health issues experienced by women throughout the life course is vital.

“By working co-productively, in partnership with women and communities, we have a fantastic opportunity to reduce health inequalities and improve treatment options and support.

“We look forward to helping facilitate more opportunities for those with lived experience, whose voices may not have been heard before, to get involved.”

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Features

Menstruation linked to longer football injury recovery

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Football injuries during periods are more severe and take longer to heal, though menstruation does not itself raise injury rates, according to new research.

The study monitored 33 elite players competing in Spain’s top women’s football league over four seasons, from 2019/20 to 2022/23, tracking self-reported menstrual cycle data alongside injury records.

The research was led by Dr Eva Ferrer, who specialises in sports medicine at Sant Joan de Déu Hospital and is a female health specialist at the Barça Innovation Hub in Barcelona.

“We show that menstruation itself does not increase how often injuries happen,” said Ferrer.

“Although athletes were not injured more often during their period, the injuries that happened during menstruation caused three times more days lost than injuries occurring at other times of the cycle.”

Players logged bleeding and non-bleeding days, the only phases of the menstrual cycle that can be reliably identified without blood hormone testing.

A total of 852 menstrual cycles and 80 lower limb injuries were recorded, 11 of which occurred during menstrual bleeding phases.

The findings showed that injury burden was significantly higher during bleeding phases.

The burden of soft tissue injuries, affecting muscles, tendons and ligaments, was more than three times as high when injuries were sustained during bleeding days compared to non-bleeding days, with 684 versus 206 days lost per 1,000 training hours respectively.

“Hormonal levels may not cause the injury, but they may influence how severe the injury becomes and how long recovery takes,” Ferrer explained.

Low oestrogen levels may reduce muscle repair, while increased fatigue, pain and poor sleep can alter neuromuscular control.

Iron loss can lower endurance and slow recovery, and inflammation heightened during menstruation may cause worse tissue damage.

“Small modifications such as longer warm-ups, adjusted high-speed workload, or added recovery support may help reduce the severity of injuries if they occur,” Ferrer said.

The researchers said their findings have implications beyond professional football for women who exercise regularly.

“You do not necessarily need to avoid training during your period, but you may need to adapt it,” Ferrer said.

“Tracking your cycle and symptoms can help guide training intensity and recovery strategies.”

The study’s limitations include all participants belonging to the same club, the unequal number of bleeding and non-bleeding days in a cycle potentially limiting statistical power, and the absence of hormone measurements or data on external factors such as stress, sleep and nutrition.

“It supports a growing movement toward female-specific sports science instead of applying male-based research models to women,” Ferrer concluded.

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