News
SiS London: new speaker lineup unveiled – meet the innovators leading the charge in women’s health
As the countdown to SiS London continues, the SiS: Women’s Health team is scouting the most inspiring case studies in the industry.
SiS London is curating an agenda that’s not just informative, but truly impactful—packed with actionable insights, personal stories, and valuable lessons from some of the brightest minds in women’s health.
This event is all about guiding start-ups through their entire journey, from securing seed funding to scaling and achieving successful exits.
Today, we’re thrilled to introduce five new speakers who are driving innovation in women’s health. These leaders are ready to share their experiences, challenge the status quo, and empower our community.
Meet the new speakers:
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Peony Li, founder and CEO, Jude
Peony is a fearless entrepreneur who took on the notorious BBC Dragons who’ll be sharing her exceptional story. Unveiling how she built a thriving company in Jude, with over $1.4M in revenue and 13,000 customers in just 17 months. Her passion for destigmatizing conversations around women’s health will be front and centre during the Seed Panel at 9:00 AM.
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Navneet Kaur, founder and CEO, FemTech India
Navneet is a trailblazer in the women’s health space, particularly in emerging markets. She has been instrumental in advancing innovations across the Indian subcontinent. Her insights on navigating complex markets where others have failed will be a highlight of the Market Expansion Panel at 1:45 PM, where she’ll discuss the challenges and opportunities of scaling businesses in diverse regions.
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Nishant Varma, founder, OBG Access
Nishant brings a wealth of experience in guiding startups through successful exits. His journey from startup founder in 2015 to exit via acquisition by Cooper Surgical in 2021 makes him a valuable voice on our Mergers & Acquisitions Panel at 4:20 PM. This talk is your chance to gain crucial knowledge on how to build towards a successful acquisition.
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Elena Rueda Carrasco, co-founder and CEO, Dama Health
Elena is breaking barriers in personalized women’s healthcare. Join her on the Market Expansion Panel at 3:00 PM to hear how she’s navigating the complexities of expanding into the US market. Elena will share her strategies for choosing pilot regions, earning trust with healthcare providers, and adapting to diverse regulations—key insights for anyone looking to make their mark in this competitive landscape.
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Deirdre O’Neill, co-founder and chief commercial officer, Hertility
Deirdre is a co-founder and the driving force behind Hertility, a company that’s revolutionizing reproductive healthcare with innovative at-home diagnostic testing. At 10:00 AM, she will join the Growth Panel to share her experiences on Hertility’s remarkable evolution, including how the company balances rapid growth with rigorous clinical standards and leverages both direct-to-consumer and B2B strategies. Her story is a must-hear for any entrepreneur navigating growth in a competitive market.
Why you can’t miss this
SiS London is bringing together the most influential voices in women’s health to discuss the strategies that drive success in this rapidly evolving industry. These newly announced speakers add even more depth and diversity to an agenda already packed with valuable content.
Whether you’re an entrepreneur, investor, or industry leader, this event offers a unique opportunity to learn from those who are pushing the boundaries of what’s possible in women’s health.
Secure your spot—limited tickets available
With this exciting new lineup, tickets for SiS London are selling fast.
Register now to secure your seat and gain exclusive access to a event filled with opportunity, connections and talks that will shape the future of women’s health innovation.
SiS London – October 9, Electric Cinema, Notting Hill London.
Transdermal HRT best protects bone density in women with functional hypothalamic amenorrhoea, a condition that stops periods, a review of trials has found.
The meta-analysis pooled randomised clinical trials involving 692 participants and found transdermal hormone replacement therapy and teriparatide increased bone mineral density by between 2 and 13 per cent.
Functional hypothalamic amenorrhoea can follow anorexia or intense exercise. Bone mineral density measures bone strength and the amount of mineral in bone.
Around half of women with the condition have low bone mineral density, compared with about 1 per cent of healthy women, and their fracture risk is up to seven times higher.
The research was conducted by scientists at Imperial College London and Imperial College Healthcare NHS Trust.
Professor Alexander Comninos, senior author of the study and consultant endocrinologist at the trust, said: “Bone density is lost very rapidly in FHA and so addressing bone health early is very important to reduce the lifelong risk of fractures.
“Our study provides much needed comparisons of all the available treatments from all available studies.
“Clearly the best treatment is to restore normal menstrual cycles and therefore oestrogen levels through various psychological, nutritional or exercise interventions – but that is not always possible.
“The foundation for bone health is good calcium and vitamin D intake (through diet and/or supplements) but we have additional treatments that are more effective.”
When FHA is diagnosed, clinicians first try to restore periods through lifestyle measures, including psychological and dietary support, but these can fail. Guidelines then recommend giving oestrogen, though the best form was unclear.
The team reviewed all prior randomised trials comparing therapies, including oral and transdermal oestrogen, and also assessed teriparatide, a prescription bone-building drug used for severe osteoporosis.
They found no significant benefit for oral contraceptive pills or oral hormone therapy.
A recent UK audit reported that about a quarter of women with anorexia-related FHA are prescribed the oral contraceptive pill for bone loss; the study suggests using transdermal therapy instead.
Comninos said: “Our goal is simple: to help women receive the right treatment sooner and to protect their bone health in the long-term.
“We hope this study provides clinicians with better evidence to choose transdermal oestrogen when prescribing oestrogen and so inform future practice guidelines.
“Right now, millions of women with FHA may not be receiving the best treatments for their bone health.”
An AI tool cut interval breast cancers by 12 per cent in a Swedish screening trial of more than 105,000 women.
The study also found 27 per cent fewer aggressive breast cancers detected at screening when AI was used.
Interval cancers are cancers found between routine screening appointments because they were missed at the original scan. They are often more dangerous and linked to higher death rates than cancers found at screening.
The MASAI trial is described as the first large randomised study to test whether AI can improve mammography screening, which uses low-dose X-rays to examine breast tissue for signs of cancer.
The AI tool, called Transpara Detection and developed by ScreenPoint Medical, supported radiologists in analysing mammography images.
Earlier results from the same trial showed that Transpara Detection increased cancers found by 29 per cent and reduced radiologist workload by 44 per cent compared with standard double-reading, where two radiologists independently review each scan.
The latest findings indicate higher accuracy with AI support. Sensitivity, the ability to detect cancer, was 6.7 percentage points higher in the AI group while specificity, the ability to rule out healthy cases, was maintained. Results were similar across age groups and breast density levels.
Women screened with AI had 16 per cent fewer invasive interval cancers and 21 per cent fewer large interval cancers than those in the standard screening group.
The system also helps doctors assess risk more precisely by subdividing suspicious findings into BI-RADS 4 categories A, B and C. BI-RADS (Breast Imaging Reporting and Data System) is a standardised scale that guides whether a patient needs closer monitoring, further tests or treatment.
Ageing anxiety may accelerate biological ageing in women, with fears about worsening health linked to faster epigenetic ageing, according to new research.
The study found that greater anxiety about growing old was associated with accelerated epigenetic ageing, as measured by the DunedinPACE clock, based on biological markers in blood samples.
Epigenetic changes are shifts in how genes are switched on or off without altering DNA itself, which can influence how the body ages and functions.
“Our research suggests that subjective experiences may be driving objective measures of ageing,” said Mariana Rodrigues, a PhD student and the first author of the study.
“Ageing-related anxiety is not merely a psychological concern, but may leave a mark on the body with real health consequences.”
Researchers analysed data from 726 women in the Midlife in the US study.
Participants were asked how much they worried about becoming less attractive with age, having more health issues and being too old to have children.
Blood samples were used to assess ageing with two epigenetic clocks: DunedinPACE, which estimates the pace of biological ageing, and GrimAge2, which estimates cumulative biological damage.
The study was conducted by researchers at NYU School of Global Public Health.
Worrying about declining health showed the strongest links with epigenetic ageing, while anxiety about attractiveness and fertility was not significantly associated with biological markers.
The authors suggest health worries are more common and persist over time, whereas concerns about appearance and reproduction may fade with age.
“Women in midlife may also be multiple in roles, including caring for their ageing parents,” Rodrigues said.
“As they see older family members grow older and become sick, they may worry about whether the same thing will happen to them.”
The authors caution that the study offers a snapshot in time and other factors may influence these biological changes.
When analyses were adjusted for health behaviours such as smoking and alcohol use, the link between ageing anxiety and epigenetic ageing decreased and was no longer significant.
“Our research identifies ageing anxiety as a measurable and modifiable psychological determinant that seems to be shaping ageing biology,” said Adolfo Cuevas, associate professor of social and behavioural sciences and the study’s senior author.
They call for more research to clarify how this anxiety influences ageing over time, to guide support for those experiencing ageing anxiety.
“Ageing is a universal experience.” Rodrigues said.
“We need to start a discourse about how we as a society, through our norms, structural factors and interpersonal relationships, address the challenges of ageing.”
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