Mental health
Wysa awarded £5.3m to address girls’ mental health in rural India

Wysa has secured £5.3m to adapt a digital mental health programme for adolescent girls in rural India.
The funding comes from Wellcome and will support a scale-up study to tailor a clinically validated digital intervention for girls facing limited autonomy, restricted access to technology, lower literacy, stigma and family gatekeeping.
Digital interventions are app-based programmes that deliver guided tools to manage anxiety and low mood, and are tested to show clinical benefit.
The study will map cultural and practical barriers to access, adapt Wysa’s content and delivery to those realities, and then test effectiveness in real-world low-to-middle-income settings.
Wysa is a global platform that combines artificial intelligence and human support to provide psychological wellbeing services.
It is used by more than seven million users across 105 countries and works with healthcare providers, employers and governments including the UK’s NHS, the Ministry of Health in Singapore, and programmes in India.
“This funding allows us to go far beyond simple translation,” said Chaitali Sinha, chief clinical and research and development officer at Wysa and the study’s principal investigator.
“By working closely with academic and community partners, we aim to co-design a digital intervention that is not only clinically effective, but genuinely usable and relevant for adolescent girls living in rural India.”
India has more than 253 million adolescents, the largest such population globally.
Around half of mental health conditions begin before age 14, and suicide is among the leading causes of death for young people.
The study team includes Aparna Joshi from Tata Institute of Social Sciences, Ceire Costelloe and Patrick Kierkegaard from Imperial College London, Dhirendra Pratap Singh from Milaan Foundation, and Becky Inkster from the University of Cambridge.
Miranda Wolpert is director of mental health at Wellcome.
She said: “We are delighted to support Wysa in their work to adapt and scale up this evidence-based digital intervention to address anxiety and depression in adolescent girls across rural India.
“This funding was awarded as part of our call to find the best ways to develop and scale digital innovations for early intervention.”
Mental health
Dr-Julian helps deliver breakthrough mental health support for Black and ethnically minoritised mothers

A groundbreaking digital perinatal mental health pilot for Black and ethnically minoritised women has helped women access support faster, complete therapy at higher rates, and recover more successfully than national averages.
The partnership between digital tech company Dr-Julian and The Essential Baby Company Ltd within a new model of mental health care named haPPIE SHE Cares – who offer personalised support for women sharing their healthcare experiences, showed results well above NHS benchmarks for Black and ethnically minoritised women.
The pilot was created to help women who are less likely to use traditional mental health services during pregnancy and in the first year after giving birth.
By combining trusted community referrals, culturally aware support, and fast access to therapy through Dr-Julian’s online and virtual care platform, the programme delivered standout results.
Every woman who joined the pilot started therapy, 90 per cent completed treatment, and 74 per cent recovered; well above the NHS benchmark of around 52 per cent.
Women referred through community organisations accessed support in just one day on average, compared with around 21 days through many standard services.
Even the programme’s regular referral route reduced waits to 13 days.
The findings come as NHS leaders continue to focus on maternity inequalities and unequal access to mental health care.
Black and ethnically minoritised women can face barriers including stigma, language needs, lack of trust in services, childcare pressures, and difficulty navigating complex systems.
The haPPIE SHE Cares model was designed to break down those barriers by working with trusted community groups, offering culturally informed support, and where possible matching women with therapists who understood their background or language.
Gemma Poole for The Essential Baby Company said: “Too many women who need help feel unseen, unheard or unable to get support when they need it most.
“This project shows that when services are built around trust, culture and community, women engage, recover and thrive.
“This early success could provide a blueprint for reducing inequalities in maternal mental health care across the UK. Behind every statistic is a mother who felt supported, a family that benefited and a woman who found her voice.
“Mental healthcare must work for every community. This partnership shows that when high-quality therapy is combined with culturally responsive support, outcomes improve and women get help faster.
We are proud to have provided the therapists, virtual care systems and digital pathways behind this programme. We believe this model could help NHS organisations nationwide cut waiting times and improve recovery rates.”
Women who took part described the programme as life-changing, saying it reduced isolation, gave them confidence speaking with healthcare professionals, and made them more willing to seek help.
With growing pressure on maternity and mental health services, leaders behind the project say the pilot offers a practical solution that improves care while helping cut long waiting lists.
Plans are now being explored to expand the model through training, regional partnerships, and future funding.
Mental health
Poor sleep linked to Alzheimer’s risk in older women – study

Poor sleep may signal higher Alzheimer’s risk in older women with greater genetic risk, a study suggests.
Older women who reported poorer sleep also showed greater memory difficulties and more Alzheimer’s-related brain changes, the study found.
That pattern appeared only in women with higher genetic risk, suggesting sleep complaints may be a stronger warning sign for some women than for others.
Researchers examined 69 women aged 65 years and older taking part in the Women Inflammation Tau Study, an ongoing project focused on ageing and Alzheimer’s disease risk.
Participants completed questionnaires about their sleep quality, underwent memory testing and received brain scans measuring tau. Tau is a protein that accumulates abnormally in Alzheimer’s disease.
The study found that poorer self-reported sleep was associated with worse visual memory performance and greater tau accumulation in brain regions affected early in Alzheimer’s disease, but only among women with higher genetic risk.
Women with lower genetic risk did not show the same relationship between sleep complaints, memory and tau build-up. The finding was specific to visual memory and was not observed for verbal memory.
Researchers said the results add to growing evidence that sleep disturbances and Alzheimer’s disease may reinforce one another over time.
Previous studies have suggested that disrupted sleep can contribute to the build-up of abnormal tau proteins, while Alzheimer’s-related brain changes may also interfere with healthy sleep patterns.
Because women account for nearly two thirds of Alzheimer’s cases and frequently report poorer sleep quality than men, the researchers said sleep may represent an important and potentially modifiable risk factor in older women.
The authors noted that self-reported sleep assessments are inexpensive and easy to administer, raising the possibility that sleep complaints could help identify people who may benefit from closer monitoring or early intervention.
They also suggested that improving sleep could become a target for future Alzheimer’s prevention strategies, particularly for women at elevated genetic risk.
Mental health
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