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Menstrual health: how ‘donating your period’ could advance women’s health

Could your menstrual blood help researchers? This entrepreneur thinks so

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Karli Büchling, founder and CEO of Yoni Health

Imagine a world where women could use their menstrual blood to screen, diagnose and monitor a range of health conditions, all while contributing to valuable research and product development.

It’s not wishful thinking; it’s the bold idea of the South African entrepreneur and female health advocate, Karli Büchling, who is establishing Europe’s first period biobank.

A self-described problem solver, Büchling thinks Yoni Health could not only help millions of women manage their health, but completely transform the women’s health landscape by allowing people to donate their periods for medical research.

The process would be simple. Women would download an app, track their period, collect the menstrual blood and send it to the biobank, where the exciting part begins.

“Businesses and researchers working with us will be able to have access to the samples for research and product development; they could choose to either get us to do the research for them in our lab facilities or they could have their own scientists do the research,” Büchling explains.

That research though won’t be solely limited to female-specific health conditions.

“We are planning to go into a range of health conditions, such as ADHD, Parkinson’s, Alzheimer’s and cancer, and other areas that haven’t previously been explored,” says Büchling.

“We see a future where women can use their periods to self-diagnose and manage their health and where researchers and health professionals can provide safe and effective equitable healthcare solutions that work for the female physiology.”

Gender bias in healthcare

Around 1.8 billion people menstruate every month worldwide, meaning 800 million women and girls are on their period on any given day. Given those numbers, surprisingly little is known about menstrual blood itself.

“There are less than 400 studies done on menstrual blood – that’s compared to more than 16,000 on erectile dysfunction,” says Büchling. “We know very little about menstrual health and we have little to no education about periods.”

Historically, medical studies have excluded female participants and research data have been collected from males and generalised to females. The gender gap in medical research, alongside overarching misogyny, has resulted in real-life disadvantages for women.

“Misogyny and sexism have a lot to answer for when it comes to understanding the female body,” Büchling agrees.

“Healthcare today is based on the male physiology and it’s based on the assumption that the female physiology is exactly the same as the male physiology. Although we now know that that is not the case, we don’t understand very clearly what the differences are.”

She says: “We may not be treated as the default, but we need to move to a place where the male and the female physiologies can coexist.

“The more research we can do, the more data we can collect, the more analysis we can complete, the better solutions and innovations we can create that could serve the female physiology in its entirety.”

Things won’t change over night, the entrepreneur admits, but she remains optimistic.

“I made it my mission to make women’s health research more accessible not only to businesses and researchers, but to every single person who wants to contribute.

“I want to be an enabler and I want the biobank to be part of that.”

Yoni Health’s biobank is expected to launch in 2025. Join the waiting list at yoni.health

Insight

Scaling startups risk increasing gender gaps, study finds

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Rapidly scaling startups often make rushed hiring choices that disadvantage women, a recent study has found.

The findings draw on more than 31,000 new ventures founded in Sweden between 2004 and 2018.

Researchers at the Stockholm School of Economics report that in male-led startups, scaling reduces the odds of hiring a woman by about 18 per cent, and the odds of appointing a woman to a managerial post by 22 per cent.

Mohamed Genedy is co-author and postdoctoral fellow at the House of Innovation, Stockholm School of Economics.

Genedy  said: “During those moments of rapid growth, even well-intentioned leaders can fall back on familiar stereotypes when assessing who they believe is best suited for the role.”

The patterns emerge even in Sweden, regarded as a highly gender-equal national context.

Founders with human resources-related education counteract these challenges.

In ventures led by founders with HR training, the odds of hiring a woman increase by more than 30 per cent, and the odds of appointing a woman to a managerial role increase by 14 per cent for the same level of growth.

Genedy said: “When founders have experience with structured hiring practices, the gender gaps shrink, and in some cases even reverse.

“This shows that getting the basics of HR right early on really pays off.

“When things start moving fast, founders with HR knowledge are less likely to rely on biased instincts and more likely to hire from a broader talent pool.”

Prior experience in companies with established HR practices also helps, though to a lesser degree.

It raises the likelihood of hiring women as ventures scale, but does not significantly affect managerial appointments.

The study additionally shows these patterns are not driven by founder gender alone.

Even solo female-led ventures display similar tendencies when growing rapidly, though to a somewhat lesser degree.

In female-dominated industries, rapid growth increases the hiring of women for regular roles but still reduces the likelihood that women are appointed to managerial positions.

“When scaling accelerates, cognitive bias kicks in for everyone. Female founders are not immune to these patterns,” said Genedy.

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Entrepreneur

Midi Health closes US$100m Series D

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Midi Health has closed a US$100m Series D, lifting the menopause care provider to a valuation above US$1bn and achieving unicorn status.

The company, originally focused on virtual menopause care, says it will expand to what it calls lifelong care, adding cardiology, obesity management, autoimmune survivorship and longevity services.

Joanna Strober is co-founder and chief executive officer of Midi Health.

She said: “This is validation for the movement we’re leading.

“Women’s health has been treated like an afterthought for too long.”

Midi reports it now sees more than 25,000 patients per week and has insurance coverage reaching 45 million women nationwide.

To support scale, the firm is rolling out a proprietary artificial intelligence engine intended to slot into clinical workflows.

It analyses patient charts before virtual visits to help personalise care, automates triage and documentation, and reviews data on midlife women to refine protocols.

The company has also strengthened its leadership. Jason Wheeler, formerly in senior finance roles at Tesla and Google, has been appointed chief financial officer. He joins chief marketing officer Melissa Waters, previously at Meta and Lyft, and chief commercial officer Matt Cook.

Each year, about two million women in the US enter menopause.

Untreated symptoms are estimated to cost the economy US$25bn annually.

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News

Women’s telehealth company WISP acquires TBD Health

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Women’s telehealth company Wisp has acquired TBD Health, a sexual health platform, in its first acquisition and expansion beyond direct-to-consumer care.

The deal adds TBD Health’s diagnostics infrastructure and hospital partnerships to Wisp’s platform, which the company says serves 1.8 million patients across the US.

Wisp, which describes itself as the largest women’s telehealth company in the US, said the acquisition marks a move into enterprise and hybrid care models that combine consumer-first digital care with hospital systems, enterprises and public health programmes.

TBD Health operates a sexual health and diagnostics platform across all 50 states, combining routine STI and HIV testing, virtual clinical support, and partnerships that help remove cost barriers for patients.

The company has established relationships with Mount Sinai Health System, San Francisco AIDS Foundation and Planned Parenthood Direct.

Monica Cepak, chief executive of Wisp, said: “This acquisition reflects where healthcare is going and where women have been left behind.

“TBD Health brings the infrastructure and partnerships that allow us to move into hybrid and enterprise care quickly, while staying true to Wisp’s patient-first approach.

“Together, we are making preventative care more accessible especially to women and integrating them into proven care models.”

The companies say gaps in access remain in sexual health and preventive care, particularly for women.

While women account for 19 per cent of new HIV diagnoses in the US, they remain underserved by existing prevention models, which have historically been designed and marketed for men.

Of the 2.4 million people eligible for PrEP, a medicine that reduces the risk of getting HIV, only around 25 per cent are currently enrolled.

Daphne Chen, co-founder of TBD Health, said: “By joining forces with Wisp, we can provide partners with a turnkey solution for PrEP along with sexual health diagnostics and care that integrates seamlessly into their existing workflows, ensuring no patient falls through the cracks.”

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