First-of-its-kind research to examine impact of cycle syncing on menstrual symptoms

A first-of-its-kind study is set to examine the impact of the cycle syncing method on menstrual cycle symptom burden – the total number of symptoms – and symptom severity.
The cycle syncing method was first introduced in Alisa Vitti’s book In the FLO (HarperCollins, 2020), who is founder of FLO Living, which will be conducting the study, backed by femtech innovators Mira, Hello Inside, and Citruslabs,
The method aligns nutrition, exercise, and lifestyle choices with the four phases of the menstrual cycle. By adjusting calorie intake, food type, workout intensity, and other daily habits, the method aims to support blood sugar, cortisol, and progesterone levels, helping to reduce hormonal symptoms throughout the month.
“We’re living in historic times for women’s health,” says Alisa Vitti, founder of FLO Living.
“With the rise of femtech solutions, women have more control over their hormonal health than ever before. Our partnership with Mira, Hello Inside, and Citruslabs demonstrates how the femtech community can work together to push research forward. Most importantly, it lays the foundation for a new standard of care that integrates dietary and lifestyle interventions with pharmaceutical options – helping women receive more holistic, research-backed support.”
Women’s health research remains critically underfunded, and menstrual health is still widely misunderstood. This study aims to change that by providing gynaecologists and healthcare professionals with evidence-backed confidence in a practical, non-pharmaceutical approach that can be used between annual visits.
“Women’s health remains one of the most underserved areas in scientific research, and the menstrual cycle is still largely misunderstood,” says Susanne Mitschke, co-founder and CEO of Citruslabs.
“This collaboration marks a historic step toward closing that gap. At Citruslabs, we’re honoured to be part of this initiative—validating cycle syncing through robust clinical evidence and championing a new era of research that finally centres on women’s lived experiences.”
At the heart of the study is real-time data tracking to measure how the cycle syncing method influences blood glucose levels, hormone patterns, and menstrual symptoms.
By leveraging Hello Inside’s metabolic health insights, Mira’s hormone tracking expertise, and Citruslabs’ research capabilities, the study will offer clinical validation for a lifestyle-driven approach to hormone health.
“We are thrilled to be at the forefront of advancing women’s health research alongside the brilliant teams at FLO Living and Mira Health,” said Mario Aichlseder, CEO and founder of Hello Inside.
“By combining their expertise in menstrual health and fertility with Hello Inside’s metabolic health insights, we are uncovering invaluable data on how women’s bodies function at all life stages. This partnership is unlocking the powerful signals of the female body, giving women deeper insights into their health and empowering them to take control.”
“At Mira, we believe data is power – especially in women’s health,” said Sylvia Kang, CEO and founder of Mira.
“This study is a critical step toward understanding how Cycle Syncing affects hormone levels, symptom severity, and metabolic health. If successful, this research could provide doctors with a trusted, non-invasive way to help women manage PMS, cramps, and heavy bleeding – while also setting a new standard for gender-specific health research.”
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