Cancer

A new study has revealed that the HER2DX diagnostics test impacts clinical decision making in early-stage HER2-positive breast cancer, leading to modifications in treatment plans. Developed by Reveal Genomics, HER2DX was shown to impact treatment decisions in a cohort of 297 patients with stage I-III HER2+ breast cancer across multiple hospitals in Spain. The primary [...]

Researchers have identified a novel trigger of a deadly form of ovarian cancer: a subset of progenitor cells that reside in fallopian tube supportive tissue, or stroma. The discovery of these high-risk cells could pave the way for better approaches to prevent and detect high-grade serous ovarian cancer (HGSOC), the most common form of ovarian [...]

In a new study, IgE antibodies have been shown to help activate monocytes  - a type of immune cell - making them more effective at attacking cancer cells, and trigger an increase in inflammatory signals that help the immune system fight HER2+ tumours. HER2+ tumours are commonly found in breast and other cancers, such as [...]

Breast density plays a significant role in both the risk of breast cancer diagnosis and the sensitivity of mammography, which may affect screening practices, new research has shown The study showed that women with dense breasts had a 1.8 times higher likelihood of being diagnosed with breast cancer compared with women with less dense breasts. [...]

Among postmenopausal women with a history of cancer, taking more daily steps and engaging in moderate-to-vigorous physical activity were both associated with a significantly reduced risk of death from cardiovascular disease, according to a new study. Cancer survivors are at an increased risk of death from cardiovascular disease, according to a 2019 scientific statement from [...]

A new study helps explain why Triple-negative breast cancer patients with obesity-driven diabetes often have worse outcomes, and suggests a potential way to improve treatment for these patients. At present, oncologists do not consider patients with breast cancer and obesity-driven diabetes differently in any significant way from patients with breast cancer who are otherwise healthy. [...]

By Steven Chen, chief medical Officer at medtech firm ImpediMed. As cancer survival rates continue to climb, healthcare providers must address a critical yet often overlooked long term risk for breast cancer patients and survivors: lymphedema. This condition, characterised by the buildup of protein-rich lymph fluid in tissues, can significantly impact survivors' quality of life [...]

Despite similar availability of diagnostic technologies to women of different racial and ethnic groups, significant disparities were seen in who actually received same-day diagnostic services and biopsies after abnormal mammogram findings, new research shows. Even when breast-care facilities had the necessary technology and capabilities, minority groups were less likely than white women to receive diagnostic [...]

The 2024 Chinese Society of Clinical Oncology Breast Cancer (CSCO BC) has published new guidelines that integrate cutting-edge international research with Chinese clinical evidence - including highlighting the crucial role of targeted therapies for HER2-positive breast cancer. The guidelines also emphasise the growing impact of immunotherapy in triple-negative breast cancer (TNBC), and outline the strategic [...]

Using AI in mammography screening can significantly increase cancer detection rates, according to a landmark clinical trial involving more than 105,000 women. The Mammography Screening with Artificial Intelligence (MASAI) trial, in Sweden, found that using AI in increased cancer detection by 29 per cent and resulted in a 44 per cent reduction in the screen-reading [...]