Cancer

The search for more effective treatments for deadly metaplastic breast cancer has uncovered two drugs with the potential to interrupt disease progression. US researchers examined the biology of metaplastic breast cancer, comparing it to non-metaplastic triple negative breast cancer. They discovered metaplastic breast cancers typically exhibit two unique signaling pathways in their cell interaction. Researchers [...]

The contraceptive pill could help to reduce the risk of ovarian cancer in one in four women, AI-driven research suggests. A new study which used AI to screen for risk factors of ovarian cancer, found that the oral contraceptive pill reduced the risk of the condition by 26 per cent among women who had ever [...]

A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous cervical lesions, according to the results from a Phase 2 clinical trial. In those with grade 3 cervical intraepithelial neoplasia (CIN3), cells are already on the path toward malignancy. If left untreated, approximately one-third of these cases progress to cervical cancer [...]

There has been a "shocking" decline in testing for cancer in women across the globe, a new report has revealed. Only 10 per cent of women surveyed worldwide said they were tested for any type of cancer in the past year, down two percentage points from the first two years of the Hologic Global Women’s [...]

Telephone-delivered acceptance and commitment therapy (ACT) is beneficial for reducing fatigue’s interference with functioning and improves the quality of life for survivors of metastatic breast cancer, a new study has revealed. Fatigue is a significant challenge for people with metastatic breast cancer, affecting up to 63 per cent of patients and severely impacting daily functioning. [...]

A clinical trial investigating the treatment TIVDAK for cervical cancer has shown positive results. The topline results from the global Phase 3 innovaTV 301 study demonstrated a clinically meaningful improvement in overall survival with TIVDAK treatment for patients with previously treated recurrent or metastatic cervical cancer compared to chemotherapy. According to the results, TIVDAK demonstrated [...]

A new, at-home cervical cancer screening test will be launched with the backing of US$10m in funding. The Teal Wand, a at-home screening device and telehealth platform, , is currently under FDA review and and developer Teal Health and said it hopes to increase uptake of screenings with the device. The industry has shifted toward [...]

A clinical trial has found that, in patients with high-risk HER2-positive breast cancer, post-surgery, or adjuvant, treatment with trastuzumab emtansine (T-DM1) reduced the long-term risk of death or invasive disease by 46 per cent and improved survival compared to trastuzumab alone. The findings provide long-term evidence that T-DM1 is an effective adjuvant treatment for this [...]

Researchers have discovered how specific protein regions contribute to breast cancer, potentially paving the way for new treatment. The discovery also offers scientists new tools and ideas beyond breast cancer, as similar protein regions are involved in many other diseases. The study focuses on what is known as the oestrogen receptor, a protein linked in [...]

A new study underscores the potential of the RAD51 biomarker in tailoring treatment strategies in patients with early breast cancer. A test based on the detection of the RAD51 protein as a functional biomarker of homologous recombination repair (HRR) is currently being validated in the stratification of patients with cancer associated with deficiency in this [...]