News
Femtech World Awards 2025: Winners revealed
Femtech World is delighted to reveal the winners of this year’s Femtech World Awards, sponsored by Planned Parenthood.
The winning entries were announced on Wednesday afternoon at a virtual event attended by the shortlisted companies and candidates.
Many thanks to everyone who attended the event, and to all the entries and, of course, the sponsors that made it all possible.
Femtech World Awards 2025 Winners:

Winner:

Shortlist:
Saskia Hale, Imperial College London
Mira

Winner:

Shortlist:
Donia Youssef
Plexaa

Winner:

Shortlist:
FlowSense
OhmBody

Winner:

Shortlist:
Caramma
Curio

Winner:

Shortlist:
ARK Surgical
Hera Biotech

Winner:

Shortlist:
Gameet
Matrice Lab

Winner:

Shortlist:
Enlight
Headspace/Spring Fertility

Winner:

Shortlist:
Aeva Health
Future Fertility

Winner:

Shortlist:
Eli
Mira

Winner:

Shortlist:
Future Family
Hinge Health

Winner:

Saskia Hale, Imperial College London
Diagnosis
Lung cancer drug shows breast cancer potential
Ovarian cancer cells quickly activate survival responses after PARP inhibitor treatment, and a lung cancer drug could help block this, research suggests.
PARP inhibitors are a common treatment for ovarian cancer, particularly in tumours with faulty DNA repair. They stop cancer cells fixing DNA damage, which leads to cell death, but many tumours later stop responding.
Researchers identified a way cancer cells may survive PARP inhibitor treatment from the outset, pointing to a potential way to block that response. A Mayo Clinic team found ovarian cancer cells rapidly switch on a pro-survival programme after exposure to PARP inhibitors. A key driver is FRA1, a transcription factor (a protein that turns genes on and off) that helps cancer cells adapt and avoid death.
The team then tested whether brigatinib, a drug approved for certain lung cancers, could block this response and boost the effect of PARP inhibitors. Brigatinib was chosen because it inhibits multiple signalling pathways involved in cancer cell survival.
In laboratory studies, combining brigatinib with a PARP inhibitor was more effective than either treatment alone. Notably, the effect was seen in cancer cells but not normal cells, suggesting a more targeted approach.
Brigatinib also appeared to act in an unexpected way. Rather than working through the usual DNA repair routes, it shut down two signalling molecules, FAK and EPHA2, that aggressive ovarian cancer cells rely on. FAK and EPHA2 are proteins that relay survival signals inside cells. Blocking both at once weakened the cells’ ability to adapt and resist treatment, making them more vulnerable to PARP inhibitors.
Tumours with higher levels of FAK and EPHA2 responded better to the drug combination. Other data link high levels of these molecules to more aggressive disease, pointing to potential benefit in harder-to-treat cases.
Arun Kanakkanthara, an oncology investigator at Mayo Clinic and a senior author of the study, said: “This work shows that drug resistance does not always emerge slowly over time; cancer cells can activate survival programmes very early after treatment begins.”
John Weroha, a medical oncologist at Mayo Clinic and a senior author of the study, said: “From a clinical perspective, resistance remains one of the biggest challenges in treating ovarian cancer. By combining mechanistic insights from Dr Kanakkanthara’s laboratory with my clinical experience, this preclinical work supports the strategy of targeting resistance early, before it has a chance to take hold. This strategy could improve patient outcomes.”
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