Entrepreneur
Interview: Closing the gap in care for high-risk pregnancies

Pregnolia is on a mission to transform pregnancy care by bringing an often-overlooked biomarker into clinical practice. Stephanie Price speaks to founder and CEO Dr. Sabrina Badir to find out more.
Paying closer clinical attention to cervical stiffness could hold the key to better outcomes for high-risk pregnancies.
That is according to Pregnolia, a Swiss university spin-out founded in 2016, which is working to improve pregnancy care through the detection of cervical changes that contribute to the risk of preterm birth.
Its technology measures the stiffness of the cervix to aid pregnancy management, providing quantitative data to support clinical decisions quickly.
The company emerged out of research at ETH Zürich university and the University Hospital in Zürich into changes in cervical stiffness during pregnancy.
“During our research, we identified cervical stiffness as a critical yet overlooked biomarker in pregnancy,” says Pregnolia founder and CEO, Dr. Sabrina Badir.
“This insight became the foundation for the Pregnolia system – a CE-marked and patented medical device that enables objective and precise measurement of cervical stiffness.
Badir says that one in 10 babies are born too early, resulting in consequences such as higher risk of death, underdeveloped lungs, neurological impairment and chronic illness – causing high costs for families and healthcare systems.
Driven by a mission to improve prenatal care and tackle some of the most pressing unmet needs in obstetrics, Badir explains that Pregnolia’s goal is to detect changes in cervical stiffness earlier and accurately measure the changes.
According to Badir, the Pregnolia system outperforms traditional methods, which focus on evaluating cervical length and dilation using ultrasound techniques, and reduces the risks associated with preterm births, as well as assessing cervical readiness for labour induction.
“With this platform technology, we support clinicians in making earlier and better-informed decisions in pregnancy care, ultimately improving outcomes for mothers and babies worldwide.
“Our long-term vision is clear: to bring cervical stiffness into clinical routine – not only to improve care for high-risk pregnancies, but ultimately to enable universal screening and make pregnancy monitoring more precise, proactive, and equitable.”
As the world’s first CE-marked and patented medical device for measuring cervical stiffness, Badir explains that the system consists of two components including a reusable control unit and a sterile, single-use probe.
“The system uses a gentle aspiration technique,” says Badir. “When the probe is placed on the cervix, it gradually applies a controlled vacuum that gently lifts the tissue.
“Once the cervix lifts by four millimetres, the system records the pressure needed to reach that elevation. The stiffer the tissue, the more pressure is required. This value is shown immediately as the Cervical Stiffness Index (CSI).
“The Pregnolia system provides a fast, easy-to-use, and objective measurement. Cervical stiffness has shown promising diagnostic performance, even outperforming cervical length measurement by ultrasound in certain clinical situations.
“The technology is scalable and suitable for use in both high-resource and low-resource settings.”
Badir explains that Pregnolia is now working with OBGYN experts to integrate cervical stiffness assessment into clinical practice by developing digital companion tools, expanding clinical validation, and preparing for inclusion in national guidelines and reimbursement frameworks.
The Pregnolia system originated from Badir’s doctoral research at ETH Zurich in collaboration with the University Hospital Zürich which led to the development of a new method to quantify cervical stiffness.
“This interdisciplinary environment – where engineering met obstetrics – was the perfect setting for innovation.
“Together with clinicians, we identified the lack of objective tools to assess cervical readiness as a major limitation in prenatal care.
“I’m proud that what began as an academic idea is now a certified medical device with the potential to redefine standards of care in obstetrics.
“We’re also proud to have secured over [USD$3.77m] in non-dilutive funding to support our development efforts. In 2019, Pregnolia was awarded a prestigious €1.5m grant from the European Union under the Horizon 2020 SME Instrument, which is now part of the EIC Accelerator programme.
“This support enabled us to scale up production and prepare the Pregnolia system for market introduction in Europe.
“Beyond the financial contribution, the EU’s backing was also a strong endorsement of the impact and innovation behind our technology, and it played a key role in helping us raise over [USD$12.58m] in equity funding to date.”
With preterm birth being one of the leading challenges for maternal health and newborn health, Pregnolia is working to support the unmet need for sufficient risk measuring tools.
Badir says that despite decades of research and various public health initiatives, current tools for assessing the risk of preterm birth remain insufficient.
“Ultrasound-based cervical length, digital exams, and biochemical markers often lack sensitivity and reproducibility,” says Badir.
“Many at-risk women go undetected, while others receive unnecessary treatment due to false positives.
“The Pregnolia system addresses this gap by providing an objective, point-of-care measurement of cervical stiffness, a new biomarker for the risk of preterm birth.”

The Pregnolia system supports clinical decision-making in both symptomatic women, helping triage patients more precisely and avoiding overtreatment, and in asymptomatic high-risk women, helping to detect mothers that may benefit from early interventions.
“In the future, cervical stiffness could also become an important parameter for guiding induction of labor, which is becoming increasingly common and complex,” says Badir.
“By improving risk stratification and supporting clinical decisions, Pregnolia has the potential to reduce unnecessary interventions, allocate resources more efficiently, and improve outcomes, especially in health systems with limited capacity.”
Pregnolia was the winner of the Femtech World OBGYN Innovation of the Year Award 2025, sponsored by elitone by Elidah.
The award, says Badir, recognises not the technology and the collective effort behind it.
“It energises us for the next phase of our journey. Pregnolia is CE-marked and ready for market entry in Europe. But through our collaborations, especially with clinical leaders in the UK, we’ve learned that the value of our innovation can be expanded even further.”
Badir explains that Pregnolia is now investing in additional clinical studies to support broader adoption, reimbursement, and integration into clinical routines.
“At the same time, our business development efforts are focused on identifying the right strategic partner, ideally one with established commercial operations, who can help maximise the value and reach of Pregnolia.”
This year, the company will also be advancing new clinical indications based on cervical stiffness, progressing its US regulatory strategy, including FDA discussions and raising further funds.
“Bringing a new diagnostic technology into clinical practice is never a solo effort. At Pregnolia, one of our greatest strengths is the global network we’ve built,” says Badir.
“This collaborative ecosystem has been instrumental in advancing our clinical research, generating the evidence needed to build trust, shaping regulatory strategies, and exploring adoption pathways in diverse healthcare settings.
“But it’s also a reflection of how we work: we listen, we learn, and we co-develop with those closest to patient care.
“We believe this network-driven approach is not only key to Pregnolia’s success, but a model for how innovation in obstetrics can and should evolve: rooted in science, focused on clinical impact, and built through global collaboration.”
Entrepreneur
Women’s Health Week Europe 2026 opens pitch applications for mainstage showcase at The Emirates Stadium

Women’s Health Week Europe 2026 has opened applications for its flagship start-up Pitches, giving women’s health innovators the chance to present on the mainstage at The Emirates Stadium in London on 7-8 October.
16 finalists will be selected across two categories: Medical Devices & Therapeutics and Consumer & Tech, with the shortlisted companies receiving the opportunity to pitch in front of 700+ investors, corporates, other innovators and strategic partners actively seeking solutions that can scale.
Two categories, one stage
The Medical Devices & Therapeutics category is open to companies working across medical devices, therapeutics and pharma innovation, regulated digital health, and deep-tech or science-led platforms.
The Consumer & Tech category covers consumer health and wellness brands, digital health platforms, wearables and connected data, employer and payor-led solutions, and commerce and marketplace businesses.
Any company treating a condition that affects women exclusively, differently, or disproportionately is eligible to apply.
Applications are completely free, so what do you have to lose?
Apply to pitch at WHW Europe 2026 now.
What’s in it for you?
Unmatched exposure
Present in front of 700+ investors, corporates, clinicians, and strategic partners actively seeking solutions that can scale.
With WHW Europe 2026 relocating to The Emirates Stadium and expanding to 700+ attendees across two stages, the 2026 edition represents the largest platform the series has offered to date.
A proven platform
The WHW Pitch Sessions have become one of the most commercially significant showcases in women’s health, with previous cohorts including companies that have gone on to raise investment and secure major strategic partnerships. 2024 alumni BoobyBiome, closed a £2.5M seed round in the year following their pitch at WHW Europe.
The Watchlist
All registered applicants will have the opportunity to be featured in The Watchlist, WHW Europe’s official directory of women’s health innovators to know, giving companies visibility beyond the pitch stage itself.
Applications close 28 August 2026.
Entrepreneur
Liverpool uni secures £18.m for women’s health studio and life-saving tech

The University of Liverpool has secured £1.8m to test a device for postpartum bleeding and launch a new women’s health studio.
The PPH Butterfly is designed to help control postpartum haemorrhage, which is severe bleeding after childbirth and a leading cause of maternal death worldwide.
The funding will support research into how the device can be used in clinical practice and generate evidence to inform its wider adoption.
The university has launched the Women’s Health Innovation Studio, known as the WIN Studio, alongside the project.
The £1.8m initiative is predominantly funded by the National Institute for Health and Care Research, which is providing £1.5m, with additional support from the university.
The PPH Butterfly project will involve a multi-centre clinical trial across the UK and a global feasibility study looking at how practical it would be to use the device in different healthcare settings.
The WIN Studio is led by Andrew Weeks, professor of international maternal health care at the University of Liverpool and a senior investigator at the National Institute for Health and Care Research, and Dr Teesta Dey, a tenure track fellow in the department of women’s and children’s health.
Dr Dey will also lead the PPH Butterfly project.
Its work will cover conditions linked to female biology, including endometriosis, menopause and pregnancy-related complications.
It will also support technologies for diseases that affect women differently or disproportionately, even when they are not usually classed as gender-specific conditions.
Dr Dey said: “Women’s health has often been marginalised within healthcare systems and innovation markets, resulting in treatments, devices and care models that fail to adequately account for women’s specific needs. WIN Studio seeks to change this status quo and reconfigure how health technologies are conceived and delivered.
“The funding from NIHR for this £1.8m project is precisely the kind of innovation the WIN Studio exists to foster: clinically urgent, women-centred, and with the potential to save lives at scale.”
The studio recently hosted an event at Liverpool Women’s University Hospital as part of the Liverpool City Region Combined Authority’s Innovation Investment Fortnight.
Seven innovations are currently undergoing clinical testing through the studio, with three developed internally.
The studio will work closely with NHS University Hospitals Liverpool Group and provide clinical, regulatory and commercial support to people developing women’s health technologies.
It will also involve patients and members of the public in shaping research priorities and product development.
Its wider programme includes collaborations involving clinicians, engineers, economists, academics and policymakers.
The project team says the PPH Butterfly is a simple, low-cost device designed to control severe bleeding quickly and with minimal training.
According to the team, postpartum haemorrhage causes around 70,000 deaths globally each year, equal to about one death every seven minutes.
The device previously received £1.1m in funding from the National Institute for Health and Care Research.
The latest £1.5m grant will support a randomised UK trial, in which participants are allocated to different treatment groups by chance, and a global feasibility assessment.
Weeks said: “In an area where women face deep health inequalities, WIN Studio has a vital role to play. By working in partnership with the NHS, local government and communities, we can ensure that research leads to real-world impact.
“Liverpool has a highly integrated ecosystem of academic, clinical and commercial expertise. By bringing these together under a single platform, the WIN Studio aims to act as a national exemplar for equitable health innovation. Transforming the way medical technologies are developed is essential to addressing gender disparities in healthcare outcomes.”
Another product supported by the university, the LifeStart Trolley, has already reached commercialisation.
The small mobile resuscitation trolley allows newborn care to be carried out at the bedside while the baby’s umbilical cord remains intact, enabling delayed cord clamping.
Delayed cord clamping means waiting before cutting the cord so blood can continue flowing from the placenta to the baby after birth.
Clinical trials conducted around 10 years ago found that life-saving care could be provided successfully at the bedside using the trolley.
It was later commercialised by Inspiration Healthcare and is now used in more than 70 UK maternity units and in 36 countries, including Norway, Italy and the US.
News
Why proven women’s health innovations still can’t find a home

By the Health Innovation Exchange
For more than a decade, femtech’s scale gap has been treated as a funding problem. What if that diagnosis is incomplete?
Despite growing attention, women founders still receive just 2 per cent of global venture funding, and years of advocacy have failed to shift the needle.
This persistence is no longer just a concern; it signals a deeper structural failure.
This is not just a funding gap. It is a system failure.
As Pradeep Kakkitill, founder and CEO of the Health Innovation Exchange (HIEx), argues, the sector continues to operate on a flawed assumption.
The belief that better support to founders alone will unlock scale overlooks the deeper structural constraints that determine whether the innovation is adopted at all.
Barriers That Go Beyond Capital
These insights are not theoretical. Global research reinforces that these challenges are not isolated, highlighting structural, financial and systemic barriers that shape how women-led and under-represented ventures access funding, markets and pathways to scale.
Importantly, these findings are not draw from research alone, but from the lived experiences of women and under-represented founders themselves.
Across HIEx-led interviews and focus group discussions conducted as part of the Reckitt Catalyst Programme, founders repeatedly described the same challenges: fragmented financing, unclear adoption pathways, repeated cycles of proof, and systems that lacked clear routes from validation to procurement and scale.
These experiences suggest that the barriers facing women-led innovation are not simply financial. They are structural.
Many high-potential ventures are not failing because funding is absent.
They are failing because the systems that determine scale, including public procurement, regulation and financing, are not built to move proven solutions beyond pilots into widespread adoption.
This is not a founder problem. It is a system design failure.
Beneath these structural constraints sits a more persistent challenge. Entrenched attitudes shaped by unconscious bias continue to influence decision making.
Across investment and public-sector systems, innovation led by women and underrepresented founders is still frequently perceived as higher risk.
These perceptions shape how opportunities are evaluated, increase the burden of proof placed on founders, and slow decision making. In practice, this results in systematically higher barriers to both funding and adoption.
Systems Unable to Absorb Innovation
Dr. Abas Hassen, lead executive officer for health innovation and quality at Ethiopia’s Ministry of Health, underscores this point.
The primary constraints are not about innovation quality, but about the systems that determine adoption and scale, including procurement, regulation, financing and delivery.
He identifies three persistent challenges: institutional resistance to change, “pilot purgatory” where solutions are repeatedly tested but not integrated into public systems, and a disconnect between what external funders support and what governments can sustain.
Ethiopia’s response reflects a broader shift. Innovation is no longer treated as isolated pilots, but as a structured component of system design.
The country’s system-led innovation model combines regulatory pathways, prioritisation frameworks and structured testing environments to embed innovation directly within the health system.
The implication is clear.
Scaling innovation is not only about accelerating individual ventures alone. It is about strengthening the systems that determine whether innovation is adopted at scale.
The Missing Middle: From Pilot to Procurement
In many low- and middle-income countries, public systems remain the largest market for health and WASH solutions, accounting for the majority of service delivery and procurement.
Yet capital is deployed through models that do not reflect this reality, as scaling depends on public-sector adoption, long procurement cycles and regulatory integration rather than rapid returns.
This creates a misalignment within the financial ecosystem, where capital is structured for faster high returns, while impact depends on long-term system integration.
At its core, the challenge is the absence of clear adoption pathways.
Without structured routes from validation to procurement and system-wide use, even effective solutions struggle to move beyond pilots.
This is the “missing middle”, the gap between early validation and large-scale adoption.
The consequences of this “missing middle” are perhaps best illustrated by the founders trying to navigate it.
Temie Giwa-Tubosun, founder and CEO of LifeBank, describes her decade-old company as an “orphan” within existing financial structures, too commercial for impact investors and too impact driven for venture capital.
Businesses operating within health systems often fall between funding models that were not designed for them.
Thato Schermer, co-founder of Zoie Health, describes a similar challenge.
Even companies with strong revenue and clear demand struggle to secure funding at the right stage, as they are assessed through frameworks that do not reflect the healthcare markets.
Across interviews and focus group discussions, these patterns were consistent.
Founders described fragmented financing, unclear adoption pathways, and repeated cycles of proof, where they are asked to keep proving their solutions without a clear route to scale.
These are not isolated challenges. They reflect how innovation is funded, evaluated and integrated across the system.
The barrier to scale is not a lack of viable solutions. It is about the systems and models that are not designed to support them.
Reducing Risk Through System Design
From an HIEx perspective, a different approach is emerging, one that focuses not on fixing founders, but on designing how systems manage risk and adopt innovation.
Rather than avoiding risk, Ethiopia is working to manage it through structured processes.
The system is “risk-aware, not risk-averse.” It uses innovation sandboxes, structured testing environments within public systems that allow new solutions to be evaluated under controlled conditions.
These mechanisms, generate decision-grade evidence while limiting system-wide exposure, creating clearer pathways from validation to adoption.
When innovations are tested within public systems, they gain institutional legitimacy. This reduces perceived risk for both governments and investors and enables more confident decision making.
From Fragmentation to Coordination
Within this context, initiatives such as Reckitt Catalyst, a multi-partner platform supporting women-led health and WASH innovation to scale, play a critical bridging role.
By connecting entrepreneurs with governments, investors and technical partners, and aligning solutions with national priorities, the programme helps to create clearer pathways from pilot to procurement and scale.
But alignment alone is not enough.
As Pradeep Kakkattil notes, the climate movement offers a useful parallel. Climate progress was not driven by evidence alone. It accelerated when investors, governments, and institutions began treating inaction as the greater risk.
Sustained pressure exposed the cost of doing nothing, redefined how risk was assessed and ultimately reshaped capital allocation and policy decisions.
Women’s health and WASH innovation is now at a similar inflection point.
Despite years of evidence and advocacy, outcomes such as women receiving a fraction of global funding persist.
This is not due to a lack of solutions. It is because the systems governing investment, adoption and scale have not been sufficiently challenged.
What is required is not incremental progress.
It is a shift in what the system tolerates – how risk is defined, how capital is allocated, and how accountability is enforced.
A System at an Inflection Point
The implications are clear.
Investors must move beyond rigid funding models and deploy capital aligned to how health systems scale. Governments must build clearer pathways for testing, procurement and adoption.
Ecosystem actors must shift from supporting individual ventures, to enabling system-level integration.
The persistent funding gap is not a result of slow progress; it reflects a system operating exactly as designed. Incremental change will not shift outcomes.
What is required is a fundamental reset of how femtech is financed and scaled: from passive investment to active market-shaping, where capital, policy, and procurement work together to create real pathways to adoption.
Until that shift happens, the sector will continue to produce innovation that the market is not structured to absorb.
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