Cancer

Ovarian cancer cells quickly activate survival responses after PARP inhibitor treatment, and a lung cancer drug could help block this, research suggests. PARP inhibitors are a common treatment for ovarian cancer, particularly in tumours with faulty DNA repair. They stop cancer cells fixing DNA damage, which leads to cell death, but many tumours later stop [...]

Agilent has FDA approval for a test to identify ovarian cancer patients who may be eligible for immunotherapy. Agilent's PD-L1 IHC 22C3 pharmDx is the only FDA-approved companion diagnostic to help identify patients with epithelial ovarian, fallopian tube or primary peritoneal carcinoma whose tumours express PD-L1 and who may be eligible for treatment with KEYTRUDA, [...]

Breakthroughs in cancer care don’t only come from large institutions or fully funded labs. They also come from determined individuals, small teams, early-stage founders, clinicians with an idea, researchers testing a new approach, technologists building smarter tools and advocates redesigning how care is delivered. If you're building something that could change how we prevent, detect, [...]

An AI tool cut interval breast cancers by 12 per cent in a Swedish screening trial of more than 105,000 women. The study also found 27 per cent fewer aggressive breast cancers detected at screening when AI was used. Interval cancers are cancers found between routine screening appointments because they were missed at the original [...]

London’s shifting population is holding down breast screening uptake, experts have said, with the capital at 62.8 per cent in 2024, below the NHS’s acceptable 70 per cent threshold. The London Assembly Health Committee recently heard that the capital faces distinct challenges compared with the rest of the country and that these issues must be [...]

Testing period blood for signs of cervical cancer could offer an accurate, convenient screening option for women who avoid clinic appointments, researchers say. The current NHS test involves a nurse or doctor taking cells from the cervix, yet a third of those invited do not attend. A study of the new test, which can be [...]

A surgical procedure developed in Canada reduces the risk of the most common and deadly form of ovarian cancer by nearly 80 per cent. The strategy, known as opportunistic salpingectomy (OS), removes the fallopian tubes during routine gynaecological surgery such as hysterectomy (womb removal) or tubal ligation (having one’s tubes tied). The study analysed population [...]

A recent study published in the BJS has found that switching to the Magseed marker could significantly reduce costs from increased scheduling flexibility and reduced operating delays. Pantiora et al (2025) evaluated data from 426 patients, randomised for localisation of the tumour with either a magnetic seed or a guidewire. The results found that the [...]

AI mammography finds more cancers at screening and cuts diagnoses between screens by 12 per cent, a major trial has found. The study involving over 100,000 Swedish women is described as the first randomised controlled trial investigating the use of AI in a national breast cancer screening programme. Women who underwent AI-supported screening were less [...]

Patients in deprived and underserved areas of England will receive earlier cancer diagnosis through a new £200 million scheme to tackle postcode lotteries in cancer care. Local communities are set to benefit from the  investment, aimed at reducing cancer screening inequalities and catching more cancers early. More people survive cancer than ever before, but progress [...]