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Femtech start-up launches first virtual endometriosis centre

ELANZA Wellness aims to transform the quality of life for millions of women living with endometriosis

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ELANZA Wellness founders Brittany Hawkins and Catherine Hendy

Chronic care start-up ELANZA Wellness has launched the first virtual endometriosis centre to help women and assigned female at birth individuals better manage their symptoms from home.

EverythingEndo aims to provide patients with a personalised symptom management plan that combines scientific research, individual data and specialist support.

Members can get medications online, learn about different treatments, meet with specialist care providers and access therapeutic interventions and education virtually. 

The female-founded start-up developed the platform in collaboration with endometriosis patients, gynaecologists, advocates and holistic health providers to help people access knowledge, resources, specialised support and treatment options from the comfort of their own homes.

“People with endometriosis need better support and faster access to effective interventions,” said co-founder and CEO of ELANZA Wellness, Brittany Hawkins.

“For too long the majority of people have had their symptoms dismissed or normalised and over 70 per cent of sufferers are now left with unmanaged pain.

“It’s our aim to change that, layering data insights with specialist, compassionate care designed to take into account the mind and body.”

Hawkins’ co-founder, Catherine Hendy, said: “Endometriosis is so complex that everyone’s journey is different. We provide a supportive space for anyone looking for effective help to address their symptoms.”

In doing so, the team aims to address stark geographical disparities in care, financial barriers to treatment and health provider shortages to help patients find the right treatment.

One in ten women lives with endometriosis, a chronic condition where endometrial-like tissue grows outside the uterus.

The disease is linked to as many as 50 per cent of infertility cases, being acknowledged by public health experts as a crisis on a vast scale.

The World Health Organization (WHO) estimates that “at least” six and a half million women in the US alone have the condition, a figure that rises to as high as 190 million globally.

When accounting for hospital readmissions and repeat doctor or emergency room visits along with loss of workplace productivity, unmanaged endometriosis costs the US economy an estimated US$50bn per year. 

However, symptoms can be successfully treated and disease progression can be slowed or halted with timely intervention, which translates to higher quality of life and lower costs. 

To provide better management of diverse symptoms, ELANZA’s new service conducts an assessment of symptoms and provides private consultations with prescribing physicians and care navigators, as well as a dashboard of education and classes from a range of specialists, including reproductive health nurses, gynaecologists, pain and fertility specialists, nutritionists, breathwork coaches and acupuncturists. 

Classes are available for at-home sessions and accessed through a Peloton-style dashboard within the platform, with members working with a dedicated care navigator to document progress.

The ELANZA team follows the biopsychosocial model of care, which takes into account the social and psychosocial determinants of health.

This approach is consistent with published research showing that a multimodal approach to managing endometriosis can improve functional and quality of life outcomes for people living with endometriosis. 

We bring the latest evidence-based virtual treatments, products and services together in one place to better connect the dots, using data to faster learn what will move the needle for each individual’s quality of life,” explained Hawkins.

“That’s the exciting part: making strides in better understanding this condition so future generations don’t need to suffer.” 

The start-up, which counts a Stanford Gynecology and Obstetrics Professor Emeritus amongst its clinical advisory, emerged from Techstars New York accelerator and received funding from Human Ventures, Gaingels and the Accel Scout Fund. It has recently joined the Re/Wire development studio run by the consumer health company HALEON.

EverythingEndo is accessible from any device and works either standalone or in complementary tandem with in-office surgical and medical treatments.

For more information, visit elanzawellness.com.

Pregnancy

Women should not be pressured into an ‘ideal birth’, says health secretary

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Women should not feel pressured into an “ideal birth”, health secretary Yvette Cooper has said as she promised major maternity reform.

Cooper has returned to the Department of Health and Social Care 27 years after serving as public health minister under Tony Blair.

She said maternity and child health would be a major focus of her new role, alongside significant reforms to social care.

In an interview with the Guardian, Cooper said the changes should address any pressure on women to pursue a particular birth experience.

Families affected by maternity failures have repeatedly raised concerns that some units were reluctant to escalate medical interventions because of a preference for more natural births.

Cooper said: “I would worry about any mum feeling pressurised that there is somehow a kind of an ideal birth experience to live up to when it’s always different in every case, and you have to follow the evidence, you have to have informed choice.”

As one of her first actions as health secretary, Cooper said she intended to reintroduce binding national maternity standards.

The standards were dismantled during early Conservative NHS reforms and replaced with fragmented arrangements managed separately by individual hospital trusts.

A new maternity taskforce will draft the standards, which will have five central aims.

These include ending regional differences in levels of care and tackling racial inequalities linked to poorer outcomes in deprived areas, particularly for Black and Asian women.

Patient experiences will also form part of how standards are measured, while new targets will aim to identify underperformance before a major scandal develops.

Cooper, who became the first minister to take maternity leave while serving as a junior health minister in the early 2000s, said reports into maternity scandals had been “traumatic” to read and showed that systemic change was needed.

She said: “We’ve always said the NHS is about the cradle to the grave. I want to make it a personal crusade to put the cradle back at the heart of the NHS, and to have much more focus around maternity and child health, the very beginning of a family’s life, making that much more central to the priorities of the NHS, giving it the priority that it really deserves.”

Cooper said discussions about how maternity services could better listen to mothers’ needs had been taking place for the past two decades.

However, she said the emphasis on placing women and families at the centre of care appeared to have been lost.

She said: “It feels incomprehensible that we could be in this situation in the 2020s. I went back to look at some of the things that we’d done 25 years ago.

“And what did strike me was how much we were talking then about women and families being at the centre of care and about listening to women’s views.

“It is really shocking and distressing feeling that has somehow been lost in some of the maternity units where actually it should be the central issue.

“I had a direct interest. I was pregnant at the time. But I am really struck by it now, just feeling like there is this big gap in the priorities that the NHS has been focused on.”

Cooper said she was determined to provide a robust response to Donna Ockenden’s investigations into maternity failures at Shrewsbury and Telford and Nottingham, alongside Baroness Valerie Amos’s national investigation into England’s maternity system.

The investigations highlighted systemic clinical errors, understaffing and toxic institutional cultures. They found that hundreds of infant and maternal deaths were directly linked to failures to listen to mothers and defensive attempts to protect institutions.

Amos’s review faced criticism, including the resignation of an expert adviser over the lack of explicit warnings about “normal birth ideology”.

Families also questioned whether the review’s proposed statutory maternity commissioner would have sufficient independence.

Cooper said she remained committed to introducing the role.

She said: “In the end, the most important people in the maternity services are the mothers, babies, the families. But the point of having a maternity commissioner is to make sure that those issues are championed as part of an NHS.”

She also said reforms needed to address an oppositional culture between doctors and midwives in some trusts over when medical intervention during birth may be necessary.

Cooper said: “The thing that struck me most was the sense of women feeling they weren’t being listened to … And I think that probably does go back to issues around culture.”

Cooper, who served as foreign secretary until recently, said she was prepared for a difficult period in the health role as she sought to implement Andy Burnham’s social care reforms.

She said she remained committed to establishing the national care service announced by the prime minister the previous week.

A longstanding ally of former prime minister Keir Starmer and a former rival of Burnham in the 2015 Labour leadership contest, Cooper said she believed the change of prime minister had been necessary.

She said: “Of course it’s not easy. I really did not think it was possible to win the election when I came back into the shadow cabinet in 2022. It’s only because of what Keir did that we managed to win.

“But we had very difficult local election results … we have to respond to that. But I think we’ve got a sense of energy now.

“All of the things that Andy wants to focus on and drive are also just very much the things that that people are concerned about across the country.”

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Motherhood

One in eight mothers diagnosed with gestational diabetes, research finds

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One in eight mothers in England is now diagnosed with gestational diabetes, after diagnoses of the condition rose by 60 per cent in just five years, according to a major study.

The research found that rates of gestational diabetes increased from around 8 per cent of pregnancies in 2018 to more than 12 per cent in 2022.

Gestational diabetes mellitus (GDM) develops when the body cannot produce enough insulin to regulate blood sugar levels during pregnancy.

It is the most common complication to occur during pregnancy and is associated with a heightened risk of preterm birth, emergency caesarean section, and babies being born either larger or smaller than expected for their gestational age.

The condition is also linked to longer-term health risks for both mothers and their children.

Laura Magee is professor of women’s health at King’s College London and co-investigator on the study.

She said: “Pregnancy outcomes for women with gestational diabetes are still worse than those for women without gestational diabetes.

“Further work is required to address how control of blood sugar and timed birth can address the excess of adverse pregnancy outcomes, compared with the general maternity population.

“Follow-up after birth is also essential, as women with prior gestational diabetes are at increased risk of cardiometabolic disease, including type 2 diabetes mellitus, but also high blood pressure and elevated blood cholesterol, starting within the first year after birth.”

For the study, researchers analysed routinely collected NHS maternity data covering more than 2.3 million mothers and around 2.8 million births across 184 hospitals in England between 2018 and 2022, making it one of the largest investigations of its kind.

The study uncovered marked inequalities in both the prevalence of gestational diabetes and pregnancy outcomes more broadly.

The sharpest rises in diagnoses were recorded among Asian women, among whom rates reached around 23 per cent, and among women living in the most deprived areas, where rates climbed to about 14 per cent.

The disparities extended beyond gestational diabetes.

Black mothers were found to be more likely to experience an emergency caesarean birth, women in deprived areas were more likely to give birth prematurely, and Asian mothers were more likely to have babies born small for their gestational age.

Among these higher-risk groups, researchers found that a diagnosis of gestational diabetes further compounded the risk of preterm birth.

Rising maternal age, increasing rates of obesity and improvements in how data is captured by the NHS are all likely to be contributing to the growing prevalence of the condition, the researchers said.

Notably, they found that changes to gestational diabetes screening introduced during the Covid-19 pandemic did not meaningfully affect the overall upward trend in diagnoses, suggesting the rise reflects genuine underlying changes in the population rather than shifts in testing practice.

The researchers said the findings pointed to an urgent need to strengthen maternity services and improve support for the women at greatest risk.

Experts said the findings also carried implications that extend well beyond pregnancy itself.

Dr Sonya Babu-Narayan, clinical director at the British Heart Foundation, said the study was part of a wider pattern of research using large-scale health data to uncover hidden risks.

“Big data research studies like this, which can now analyse millions of healthcare records, are uncovering a concerning rise in conditions which raise people’s chances of having a future heart attack or stroke,” she said.

“Gestational diabetes often goes away after pregnancy, but it can increase women’s risk of future cardiovascular disease.”

Dr Babu-Narayan called on healthcare professionals to routinely ask women about pregnancy-related risk factors, regardless of how long ago the pregnancy took place.

“Healthcare professionals who want to fully understand people’s risk of heart attack and stroke should routinely ask women about risk factors unique to them, such as diabetes or high blood pressure in pregnancy – even if that pregnancy was decades earlier,” she said.

“If you are a woman who has had diabetes or high blood pressure during pregnancy, it is especially important to attend health checks when invited.”

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News

New tool identifies heart disease risk in women earlier in life

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Researchers in the US have developed a new tool designed to identify women at risk of heart disease much earlier than existing methods allow.

The findings, published in the journal JACC: Advances, highlight significant gaps in the risk assessment approaches currently used in clinical practice.

“Heart disease is the leading cause of death in women, yet existing risk tools were developed in older populations and ignore factors unique to women,” said senior author Robert Platt, professor in the Department of Epidemiology, Biostatistics, and Occupational Health and director of the School of Population and Global Health.

He noted that while pregnancy complications are known to be linked to future heart risk, there has until now been no reliable way of identifying which younger women are most at risk.

To build the tool, researchers analysed health data from more than 260,000 women in the UK aged between 15 and 45 who had given birth.

The team developed and validated a prediction model to estimate future heart disease risk, following participants for nearly four years after delivery.

The model identified several factors not included in existing risk tools that can help predict a woman’s likelihood of developing heart disease.

These include hypertensive disorders of pregnancy, gestational diabetes, preterm birth, polycystic ovary syndrome (PCOS), depression, thyroid disorders, oral contraceptive use and social deprivation.

The findings suggest that some women, particularly younger women often dismissed as low risk, may in fact face a higher risk of heart disease earlier than previously recognised.

“Millions of women who give birth each year are never considered candidates for cardiovascular risk assessment simply because of their age,” said co-author Kristian Filion, professor in the Departments of Medicine and of Epidemiology, Biostatistics, and Occupational Health.

He added that if integrated into routine postpartum care, the tool could enable earlier monitoring, lifestyle counselling or referral to a specialist, potentially helping to prevent a heart attack or stroke later in life.

The research team’s next step is to validate the model using data from Canada and the United States.

In the longer term, they hope to integrate a practical calculator into electronic health records, allowing higher-risk patients to be identified and supported earlier.

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