News
Comment: How cutting-edge femtech can remove the barriers to IVF and close the fertility gap
Hans Gangeskar, CEO of Overture Life, on harnessing lab automation to make IVF more accessible.
As infertility rates continue to rise globally, in vitro fertilisation (IVF) is an increasingly critical aspect of women’s health and reproductive freedom.
The promise that women should be able to choose when and if to have a baby remains unfulfilled without radical technological advances in IVF both to improve outcomes and to reduce prices. At current costs and success rates, IVF remains out of reach for most women due to cost and emotional burden.
IVF has recently reentered the political arena in the US, where most women must pay out of pocket for an IVF cycle can cost in excess of $20,000 (£15,800), and on average it takes 2.5 cycles to have a baby, driving the average cost of an IVF baby to around $50,000 (£39,500).
This is obviously out of reach in most cases. The conversation has centered around better insurance coverage, but that cannot address the underlying lack of capacity. IVF is supply constrained because there are not enough IVF clinics and embryology labs to meet current demand.

Overture Life CEO Hans Gangeskar
The key to expanding access, in the US and globally, is to bring down the cost of each cycle, and drastically reduce the number of cycles necessary.
We need the opposite of the development we have seen in the rest of healthcare, where the price of services increases much faster than inflation.
Driving prices down and quality up to make IVF affordable requires new technology, standardisation and automation.
The costs of infertility and IVF are not just financial, and for many couples the burden of a failed cycle and the stress of the high financial burden combine to reach a threshold where they give up.
Researchers and experts around the world continue to tell us why fertility rates are dropping. Reasons cited range from expense of child rearing, forever chemicals, diseases like cancer and long covid and more.
It is however very clear to us that the time when women want to have children has changed, and this is an area where technology can come in and deliver more reproductive freedom to address fertility obstacles head-on.
Globally, only a fraction of fertility service demand is met, and new technology must deliver lower costs but also better results. Even successful IVF generally takes multiple attempts, with attendant stresses on physical and mental health – 80% of IVF patients report symptoms of clinical depression.
Cutting-edge femtech has the ability to address the fertility gap in novel ways, especially by modernising and miniaturising the embryology lab.
Shrinking costs
One of the main drivers of the high price tag is embryology laboratory expenses, which can account for half of all IVF costs, limiting access in several ways. First, many procedures done today are still manual, resembling ones used 45 years ago. This limits viability rates, driving up the number of cycles needed for a successful IVF.
It also means the procedures remain complex, requiring highly trained staff who are in high demand. This in turn helps make it cost-prohibitive for small facilities to fully staff an embryology lab, thereby capping availability – and over 5 million women in the UK now have limited or no access to local fertility clinics.
Bringing IVF costs down is primarily a question of opening more points of care. We need to make it possible to offer IVF services alongside other medical services making it economically viable to serve only 100 IVF cycles per year, or even as low as 20.
Technology is beginning to enable this potential. In addition, the promise of automation is not just efficiency, it is the ability to standardise and iterate. And this isn’t just the ability to standardize across an industry, but to standardize between shifts in a single clinic.
IVF clinics have pioneered many advances in the field, but it is also a very manual and artisanal practice, making it hard to copy processes from one embryologist to another, let alone from one clinic to the next.
Automated technology helps standardise steps like egg freezing, intracytoplasmic sperm injection (ICSI), and embryo selection, which are prone to human error.
Together, these platforms have been shown to improve viability rates meaningfully – a huge cost savings for patients. It can also shrink the required overhead for a small facility by an order of magnitude, further lowering costs while expanding access.
An automated world
Bringing IVF services to fertility deserts first and foremost requires portability. Microfluidics, a technology popularised in medtech to bring complex processes closer to the point of care, is important for both shrinking and automating vitrification – the freezing and thawing of eggs and embryos.
Because it is a more gentle way of handling cells (eggs), microfluidics reduces osmotic stress on fragile cells, minimising egg and embryo loss. It also enables small, powerful automated devices.
Robotics is also key for any automation paradigm, generally reducing both handling time and process complexity. There is a prime opportunity for improvement when making an embryo, the most challenging task in an embryology lab.
Technology is now in use that can automate the technique known as Piezo-ICSI, a gentle and precise method to inject sperm into an egg that improves both fertilisation and blastocyst development.
Robotic ICSI has already resulted in two live births and has been shown to increase fertilisation rates to 93 per cent, compared to 89 per cent for manual methods.
Of course, the consistency of robotics also removes the potential for human variability and error, removing the potential for fatigue.
Anecdotally, some IVF clinics have noted lower success rates when complex manual procedures are performed by embryologists late in the day.
A robotic platform can also reduce inconsistency between embryologists and between labs, which translate into more consistent, better outcomes.
The third critical piece for automation excellence is advanced analytics, especially when paired with AI techniques. Technology has been deployed to improve on standard preimplantation genetic testing (PGT), which helps identify and select embryos without genetic disease.
However, standard PGT predicts embryo implantation at just 60%, leaving plenty of room for improvement. It also relies on a biopsy to remove cells from the embryo, which carries a small risk of damaging it.
Newer methods utilize metabolomics powered by machine learning. These platforms have been shown to improve implantation prediction accuracy above 80%, and can identify and discard 90% of aneuploid embryos (with chromosomal abnormalities). Because only metabolites produced by the embryo, no invasive biopsy is required, reducing the demand on embryologists while helping to identify stronger embryos.
Given the significant and growing fertility challenges around the world, and the notable gaps in access to treatment driven by cost and geography, it’s clear that we in the fertility field need to do a better job of reaching women everywhere. Because labwork is not patient-facing, its impact can be broadly underestimated or even ignored.
However, the reality is that there are multiple opportunities to improve the embryology lab through automation, improving outcomes and ensuring embryologists can spend more time with more patients.
Hans Gangeskar is CEO of Overture Life, which aims to simplify and automate the complex processes of embryology.
Insight
WUKA and Royal Yachting Association partner to support women and girls in sailing
WUKA has announced a groundbreaking partnership with the Royal Yachting Association (RYA), including RYA Scotland and RYA Northern Ireland, supporting women and girls in sailing.
Building on WUKA’s growing #TackleAnything campaign – which has already reached thousands of girls across sports in the UK – this collaboration brings practical period solutions into sailing.
Together, WUKA and the RYA are committed to breaking down barriers so periods never limit confidence, participation, or performance on the water.
Ruby Raut, WUKA founder & CEO, said: “Partnering with the RYA has been incredibly important for us at WUKA.
“Sailing is an amazing way for women and girls to build confidence, and periods shouldn’t hold anyone back from enjoying the water or reaching their full potential.
“Through this partnership and our #TackleAnything campaign, we’re proud to provide practical solutions and innovative products that help female sailors feel comfortable, confident, and free to focus on learning, performing, and having fun.
“Breaking down barriers and supporting women to tackle anything — on land, at sea, and everywhere in between – has never felt more meaningful.”
WUKA, which stands for Wake-Up Kick Ass, shares the RYA’s commitment to inclusivity and empowerment.
In 2023, WUKA launched #TackleAnything, a campaign supporting women, girls and sportspeople with periods. Since its launch, the initiative has reached 3,576 girls across 46 clubs and partnered with a range of sports across the UK – from Scottish Gymnastics to Titans wheelchair basketball – helping young athletes play without limits and stay confident, comfortable, and in the game.
The brand offers period-friendly aquatic apparel and practical solutions that help women train and compete with freedom of movement and total assurance.
Through this partnership, WUKA will provide innovative period swimwear for young sailors across key RYA programmes, including the NI Sailing Team, the RYA Scotland Performance Pathway Programme, and the British Sailing Pathways Talent Academies.
By combining WUKA’s mission to challenge stigma with the RYA’s commitment to inclusion, the partnership ensures young sailors can focus on what matters most – learning, performing, and enjoying their time on the water – with confidence and comfort. RYA members will also receive a 10 per cent discount on WUKA products.
Sailing offers incredible benefits for women and girls, but time on the water can present unique challenges -particularly during menstruation.
Together, WUKA and the RYA are providing practical solutions that remove these barriers, helping young sailors participate fully and confidently in the sport.
Sara Sutcliffe, RYA CEO, said: “At the RYA, we have been making strides to break down barriers for women of all ages to help ensure they can experience the water in a supportive and positive environment.
“From education workshops and practical sessions, we want to make sure our female sailors are empowered and this partnership is another great example of how we can demonstrate possible tools to equip them to succeed”.
This partnership is part of the RYA’s wider commitment to making sailing a sport where women and girls can thrive. Alongside initiatives such as the Female Futures Group, the Women’s Race Officials Programme and all new Talent Academy Female Future’s Camps; it demonstrates a continued focus on removing barriers and creating meaningful opportunities across every stage of the sailing.
WUKA’s involvement ensures that practical solutions are available on the water, from innovative period swimwear to support resources, helping young sailors feel fully equipped and confident during training and competition.
By integrating these tools into RYA programmes, WUKA brings a new level of comfort and assurance to female athletes, allowing them to focus entirely on performance, enjoyment, and growth in the sport.
For any women and girls looking to learn more about sailing, visit www.rya.org.uk.
For more information on WUKA visit www.wuka.co.uk.
Insight
Study links changing population to low London screening rates
London’s shifting population is holding down breast screening uptake, experts have said, with the capital at 62.8 per cent in 2024, below the NHS’s acceptable 70 per cent threshold.
The London Assembly Health Committee recently heard that the capital faces distinct challenges compared with the rest of the country and that these issues must be addressed.
Josephine Ruwende, a cancer screening lead at NHS England, said frequent moves within the rented sector and the cost-of-living crisis pushing people out of London had made it difficult to reach eligible patients, which she described as “population churn”.
She said: “This is people changing addresses and then not updating their GP, this then affects the invitation process because GP details are used to identify individuals who are eligible.
“In boroughs where we have the highest population churn, we see it strongly associated with lower uptake.”
She noted that even in the wealthiest boroughs there can be high levels of movement, with around 40 per cent of residents changing address within a year.
Such areas also tend to have more people who own second homes or spend long periods abroad, making it harder for the NHS to keep contact details up to date.
As a result, screening invitations may be sent to out-of-date addresses or to people who are overseas.
Leeane Graham, advocacy lead at Black Women Rising, which supports women of colour with a cancer diagnosis, said there were cultural barriers, fear and a mistrust of the health service due to previous experience within communities.
She said: “If you’ve never been for a breast screening before, the thought of having a mammogram can be really, really terrifying.”
Helen Dickens, from Breast Cancer Now, said other reasons included a lack of understanding of breast screening, along with concerns about discomfort, trust and practical issues such as travel.
She said: “We have amazing public transport and we feel that we’ve got great accessibility, but we also know that we don’t have screening centres in every borough.
“We know that for some women that barrier of transport and access will still be a really big reason why they’re not attending screenings.”
NHS London launched its first screening campaign last year in response to the figures, aiming to increase detection at an earlier stage.
Insight
The hidden cost of “business as usual” in gynecologic surgery
A Common Surgery with Outsized Consequences
Hysterectomy and myomectomy are among the most frequently performed surgeries worldwide.
Minimally invasive and robotic approaches have delivered clear benefits at the point of care, including shorter hospital stays, faster recovery, and fewer complications.
To remove the uterus or fibroids through small incisions, surgeons use a technique known as morcellation, in which tissue is cut into smaller pieces for extraction during surgery.
However, when tissue is cut without containment, those short-term gains can be offset by downstream harm.
The risks fall into three interconnected categories:
- dissemination of undiagnosed malignancy
- spread of benign tissue, including endometriosis and parasitic fibroids
- legal and financial exposure linked to off-label device use
Crucially, these costs often surface years after the original procedure and rarely where the original cost savings were realized.
Cancer Dissemination: A Known and Preventable Risk
The risk of occult uterine malignancy in women undergoing surgery for presumed benign fibroids is well documented.
The U.S. Food and Drug Administration has estimated this risk at approximately 1 in 350 women, prompting repeated safety communications recommending tissue containment during morcellation.
When morcellation is performed without containment, undiagnosed cancer will be dispersed throughout the abdominal cavity, effectively upstaging disease from localised to disseminated.
The clinical implications are profound, and so are the economic consequences.
Treatment costs for early-stage uterine cancer typically range from $40,000 to $60,000. Once disease becomes disseminated, costs can exceed $150,000 to $300,000, excluding indirect costs such as lost productivity, long-term disability, and caregiver burden.
Beyond treatment expenses, litigation related to morcellation-associated cancer spread has resulted in multi-million-dollar settlements, particularly during the power morcellation litigation wave of the mid-2010s. Several cases explicitly tied disease progression to tissue dissemination during surgery.
From a system perspective, a single preventable dissemination event can negate the cost savings of hundreds of minimally invasive procedures.
Benign Tissue Seeding: The Long Tail of Surgical Cost
Cancer is not the only concern.
Uncontained morcellation has also been associated with the spread of benign tissue, including parasitic fibroids and iatrogenic endometriosis, conditions that may present years after the index surgery.
Endometriosis alone represents one of the most expensive chronic gynecologic conditions. Multiple health economic studies estimate annual per-patient costs of $12,000 to $16,000, with lifetime costs exceeding $100,000, driven by repeat surgeries, chronic pain management, hormonal therapy, and fertility interventions.
While the financial impact may surface years later, downstream harm is increasingly traced back to the index procedure, including the choice between FDA-cleared containment and off-label alternatives used during tissue extraction.
Off-Label Use and the Quiet Accumulation of Liability
One of the least visible, but most consequential, dimensions of morcellation risk lies in off-label device use.
Many tissue bags currently used during morcellation are not FDA-cleared for prevention of tissue spillage during organ cutting and removal. While off-label use is common in medicine, it carries distinct legal and financial implications when complications occur.
Risk management guidance from MedPro Group, one of the largest medical malpractice insurers in the United States, has repeatedly warned that off-label use increases professional liability exposure in three key ways:
1. Burden of justification
When an FDA-cleared alternative exists, the legal burden shifts to the surgeon to prove that off-label use met the standard of care.
2. Informed consent vulnerability
Standard consent language may be insufficient for off-label device use, increasing exposure to failure-to-warn claims if complications arise.
3. Changed liability dynamics
Off-label use alters traditional liability dynamics, increasing scrutiny on clinical decision-making at the hospital and surgeon level.
Legal scholarship published in Clinical Orthopaedics and Related Research has echoed these concerns, noting that courts increasingly allow off-label status to be considered in malpractice cases, particularly when patient harm occurs and safer alternatives were available.
Recent U.S. court decisions have further reinforced that while off-label use is generally permitted, it is not immune from civil liability and, in rare but serious circumstances, criminal consequences when tied to demonstrable patient harm.
FDA Guidance Exists, Adoption Lags Behind
Regulatory expectations around morcellation are no longer ambiguous. The FDA has consistently called for tissue containment during tissue cutting to mitigate the risks of cancer and tissue dissemination.
Yet real-world adoption remains inconsistent.
A 2025 survey reported by News-Medical found widespread gaps in safe tissue containment during laparoscopic gynecologic surgery.
Respondents cited variability in training, institutional protocols, and access to FDA-cleared containment systems. Many surgeons reported reliance on improvised or non-cleared solutions despite growing awareness of regulatory and legal risk.
The result is a widening gap between guidance and practice, one that is increasingly visible to regulators, insurers, and hospital leadership.
Who Ultimately Pays?
The economic impact of uncontained morcellation does not fall on a single stakeholder.
- Hospitals face litigation exposure, rising malpractice premiums, re-operations, and reputational risk.
- Surgeons shoulder personal liability, heightened scrutiny around informed consent, and evolving standards of care.
- Payers absorb downstream oncology costs, chronic disease management, and repeat interventions.
- Patients bear the heaviest burden, including preventable morbidity, fertility loss, financial toxicity, and erosion of trust.
Taken together, these costs far exceed the price of prevention.
From Clinical Risk to Market Response
This growing recognition of risk has begun to reshape the market.
Before regulatory scrutiny intensified, power morcellation was widely adopted because it saved time, reduced operating room burden, and supported high procedural throughput.
It represented a multi-billion-dollar global market, supported by major surgical device manufacturers and deeply embedded in minimally invasive gynecologic practice.
The withdrawal of power morcellation from many hospitals did not eliminate the clinical need for efficient tissue extraction. Instead, it created a prolonged gap between surgical efficiency and acceptable risk.
That gap is now beginning to close.
With the emergence of FDA-cleared tissue containment systems designed specifically for morcellation, hospitals are reassessing whether power morcellation can be responsibly reintroduced in a manner aligned with regulatory guidance, patient safety, and liability mitigation.
This has significant implications for operating room efficiency, surgeon ergonomics, and system-wide cost management.
One example is Ark Surgical, a U.S.-focused surgical technology company advancing safety-first approaches to tissue extraction.
Its double-wall, airbag-like LapBox containment chamber was developed to support FDA-aligned morcellation while integrating into existing laparoscopic workflows, an increasingly important consideration as hospitals evaluate not just procedural efficiency, but long-term risk exposure.
Ark Surgical is currently in an active investment round, reflecting broader investor interest in technologies that address regulatory-driven risk while unlocking previously constrained markets.
More broadly, capital is flowing toward solutions that make it possible to restore clinical efficiency without reintroducing legacy risk.
The Cost Question Is No Longer “If,” but “When”
Healthcare systems already absorb the cost of uncontained morcellation through litigation, chronic disease management, repeat interventions, and loss of trust.
What has changed is visibility.
As clinical data, regulatory expectations, and market solutions converge, the question is no longer whether containment matters, but whether healthcare systems can afford to continue treating it as optional.
-
Features4 weeks agoWomen’s health enters a new era – the trends shaping femtech in 2026
-
Fertility3 weeks agoDesigner perfumes recalled over banned chemical posing fertility risk
-
Features4 weeks agoBest menopause apps and products for 2026
-
Insight1 week agoParents sue IVF clinic after delivering someone else’s baby
-
Insight2 weeks agoWomen’s health could unlock US$100bn by 2030
-
Wellness4 weeks agoHigher maternal blood pressure increases risk of pregnancy complications, study finds
-
Entrepreneur4 weeks agoXella Health closes US$3.7 million in pre-seed financing
-
Insight4 weeks agoInside the first wave of speakers confirmed for Women’s Health Week USA 2026





