Cervical screening interval for women under 50 in England to change from three to five years

Women aged 25 to 49 in England will be invited for cervical screening every five years instead of three, if they test negative for human papillomavirus (HPV), under new changes beginning 1 July.

The update brings England into line with Scotland and Wales, which have already adopted the extended screening interval for women who test negative for HPV—the virus that causes nearly all cases of cervical cancer.

According to NHS England, evidence shows that women with a negative HPV result are at very low risk of developing cervical cancer and do not need to be screened as frequently.

HPV is a common virus, and some types can cause changes in cervical cells that may lead to cancer over time.

The HPV vaccination programme, introduced in the early 1990s, is estimated to have reduced cervical cancer rates by around a quarter.

Under the new guidance, women aged 25 to 49 with a negative HPV test will be screened every five years.

Those aged 50 to 64 already follow this interval.

Dr Sue Mann, national director for women’s health at NHS England, said: “The NHS is following robust evidence on how often women need to be safely screened.

“By putting invitations and reminders straight in women’s pockets on their phones, we’re making it easier than ever to take up screening appointments.”

HPV testing is now the main method of cervical screening. If no high-risk types of HPV are detected, the risk of developing cervical cancer in the next ten years is considered very low.

This testing approach is more accurate than solely looking for abnormal cells.

Recent studies suggest screening every five years is as effective as screening every three, detecting a similar number of cancers while reducing unnecessary tests.

NHS England described the change as part of a “more personalised approach” aimed at reducing unnecessary appointments for those at low risk.

Eligible individuals will receive appointment notifications through the NHS app.

Cancer charities supported the change, while encouraging continued vigilance. Cancer Research UK urged people not to wait for a routine screening invitation if they notice any unusual symptoms, and to continue attending screening from age 25 to 64.

NHS England has previously said cervical cancer could potentially be eliminated by 2040, thanks to improved vaccine coverage and screening uptake.

Cervical cancer is the fourth most common cancer in women worldwide.

Symptoms can include unusual vaginal bleeding—such as after sex, between periods or after the menopause—heavier periods than usual, changes to vaginal discharge, or pain during sex, in the lower back, or across the pelvis.