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Future Fertility unveils ROSE™, a new AI-based egg quality tool that aims to transform donor egg programs

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As demand for egg donation grows around the world, Future Fertility is bringing transparency, predictability, and reliability to donor oocyte programs.

The company has announced the launch of ROSE—a new AI-powered oocyte quality workflow and report built specifically for egg banks and donor egg programs.

Jullin Fjeldstad is Head of Clinical Embryology and Scientific Operations at Future Fertility.

Fjeldstad said: “Egg banks have historically lacked tools to assess and manage donor oocyte quality in an objective way.

“ROSE™ brings standardisation into the equation, offering new AI-based insights and a workflow solution that optimise how donor eggs are managed, grouped, and allocated.”

With the number of IVF cycles involving donor eggs increasing globally, clinics and egg banks face rising pressure to deliver quality assurance in donor oocyte distribution.

Experts estimate that donor eggs are used in approximately 10 per cent of all cycles.

Meanwhile, the global donor egg IVF market is projected to reach $6.6 billion by 2032, up from $2.3 billion in 2022.

ROSE provides egg banks with a clinically validated, AI-powered tool that predicts the likelihood of each oocyte developing into a high-quality embryo (blastocyst).

Powered by the world’s largest dataset of oocyte images and associated reproductive outcomes, ROSE has been clinically validated for use with donor egg populations— enabling egg banks to:

  • Optimise oocyte distribution by expected blastocyst outcomes
  • Provide objective quality assurance for donor oocyte groupings
  • Track and manage donor cycles and oocyte inventory with an AI-based tool and custom workflow solution
  • Build trust with receiving clinics through intuitive, image-based reports

ROSE was developed in consultation with real egg bank partners who helped define requirements and refine the platform’s capabilities.

Dr. Catello Scarica, Scientific director at New Fertility Group, noted: “We’ve been impressed by how the ROSE tool supports quality control and decision-making in our donor cycles. It gives our team greater confidence in the eggs we distribute and enables better alignment with receiving clinics.”

WeBank’s Development Director, Dr Natalia Basile added: “ROSE is transforming how we manage donor eggs.

“The objective scores, traceability, and reporting help us organise inventory and reduce uncertainty—especially valuable when outcomes don’t meet expectations.”

From a clinical workflow perspective, the platform is designed for seamless integration. ROSE connects directly with microscopes and laser systems, allowing egg banks to capture 2D oocyte images in real time and securely upload them to the cloud.

Within minutes, the AI model—proven to be more accurate than embryologists in multiple studies—delivers predictions about blastocyst potential, with a workflow solution that manages, tracks and optimises groupings of oocytes for distribution.

Dr Danilo Cimadomo is Global Manager of AI and Data Management for Embryological Research at IVIRMA Global Research Alliance.

Cimadomo  said: “The future of egg donation lies in complementing information about egg quantity with eggs’ blastulation potential to personalise the number of oocytes allocated per recipient.

“Tools like ROSE, can help maximise success while minimising the number of surplus embryos by matching patients with an ideal number of high-quality eggs based on their unique profile.”

Rafael Gonzalez, Global Head of Sales and Commercial Strategy at Future Fertility, added: “Clinics are asking for greater confidence when it comes to donor egg quality, both recipient clinics and donor egg banks.

“ROSE provides a scalable, data-driven way to meet that demand—giving both donor labs and recipient clinics a shared, objective language to talk about egg quality.”

Insight

Designer perfumes recalled over banned chemical posing fertility risk

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Two designer perfumes have been recalled over a banned chemical linked to fertility risk and harm to unborn children.

Hello by Lionel Richie and Hot by United Colours of Benetton, both sold by discount chain Savers Health and Beauty, have been recalled in a notice from the Office for Product Safety and Standards.

The products contain butylphenyl methylpropional (BMHCA), also known as lilial, a synthetic floral fragrance classified as toxic to reproductive health.

The chemical, which mimics a lily of the valley scent, was used in many cosmetics and household products until March 2022, when it was banned in the UK and EU.

According to the notice, BMHCA can harm the reproductive system and the health of unborn children, and may cause skin sensitisation.

The Office for Product Safety and Standards said: “Affected products have been recalled by Savers Health and Beauty. Customers should return any of the above products purchased at a Savers store to the place of purchase, where they will be issued a full refund.

“Only products purchased in Savers Health and Beauty stores with the barcodes listed are affected by this recall. If you are unsure if you have one of the above products, please contact Savers Health and Beauty on help@savers.co.uk.”

The initial warning about the items was issued last month, with products recalled from customers on Wednesday.

Savers said in a statement that it would like to apologise for any inconvenience caused.

Affected products include Hello by Lionel Richie Femme and Homme in 30ml, 50ml and 100ml sizes, and Benetton Hot 100ml EDT.

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Chemotherapy may significantly impair fertility and ovarian function, study suggests

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Chemotherapy may reduce ovarian function and fertility in women, a recent study suggests.

The research examined how cancer treatment affects ovarian tissue, hormone production and ovarian reserve (the egg supply available for reproduction).

The authors found that some chemotherapy drugs can trigger oxidative stress (cell damage from unstable molecules) and apoptosis (programmed cell death) in ovarian follicles.

These effects can reduce ovarian volume, destroy growing and dormant follicles, and speed up depletion of the egg reserve.

Damage to the ovarian microenvironment can disrupt hormone production and the balance needed for follicle maturation and ovulation, increasing the risk of diminished fertility or premature ovarian insufficiency (early loss of ovarian function before 40).

The findings suggest women of reproductive age receiving chemotherapy may face reduced ovarian reserve, impaired fertility and earlier menopause compared with those not treated.

The researchers said the results support integrating fertility risk assessment and preservation into cancer care.

Clinicians should discuss possible impacts before treatment and consider referrals to fertility specialists.

Preservation options include egg or embryo freezing, ovarian tissue storage or ovarian suppression therapies, depending on individual needs.

The authors called for research into protective strategies to limit ovarian damage during treatment, and long-term studies tracking fertility outcomes in survivors.

Understanding how different chemotherapy types affect the ovaries will be key to personalised onco-fertility care.

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Fertility

Xella Health closes US$3.7 million in pre-seed financing

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Xella Health has closed more than US$3.7m in pre-seed financing as it prepares to launch a women’s precision health platform in spring 2026.

The company, which says it is approaching a 10,000-person waitlist, combines multi-omic diagnostics, longitudinal data (tracked over time) and clinician-led guidance to help women understand their biology across fertility, hormonal health, chronic conditions, early cancer detection and preventative care.

Xella says it is pioneering the use of menstrual fluid alongside peripheral blood to access biological signals that have historically been ignored.

The company claims this approach can provide insights into the root causes of menstrual irregularities and chronic pelvic pain, scores for egg quality and quantity, miscarriage risk, specific perimenopause stage, HRT personalisation guidance, genetic predispositions for reproductive cancers and whole-body ageing insights.

Kelly Lacob, co-founder and chief executive of Xella, said: “Our mission is to give women the answers and care they have always deserved.

“Xella is building the infrastructure to decode female biology–getting to the root cause of conditions that uniquely, differently or disproportionately affect women, many of which suffer from an unacceptably poor standard of care today.

“Every woman who comes to Xella works with a dedicated clinician-coach, supported by AI, to ensure that the complex data we analyse translates into meaningful, actionable health outcomes rather than more noise. This funding allows us to accelerate product development and prepare for our first launch.”

The company was co-founded by Lacob alongside Adriana Dantas, chief operating officer, and Jesus Ching, chief technology officer.

The funding round was led by Precursor Ventures, with participation from Capital F, Ulu Ventures and other funds, as well as angel investors across healthcare, diagnostics and consumer technology.

Ashtan Jordan, principal at Precursor Ventures, said: “Xella is rethinking women’s health from the ground up—starting with the insight women need to make sense of their own biology over time.

“The team is building with a rare combination of scientific depth, product intuition, and empathy for the lived realities of women, which is exactly what’s required to create a trusted, enduring platform in healthcare.”

The capital will be used to finalise product development, expand partnerships and support the company’s market launch.

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