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8 ways to improve mental health access across your menstrual cycle

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Have you noticed how some weeks you feel clear-headed and energetic, while others leave you foggy, anxious, or tearful? There’s a reason for that.

Your mental health during PMS and across your entire menstrual cycle isn’t random. It’s deeply connected to how your brain responds to shifting hormone levels.

Estrogen and progesterone don’t just affect your reproductive system; they also influence neurotransmitter activity, brain connectivity, and even the volume of certain brain regions linked to memory, mood, and emotional regulation.

Research shows that grey matter volume in areas controlling emotion changes measurably across the menstrual cycle in relation to hormone fluctuations.

This isn’t about being hormonal. It’s about understanding that your brain operates differently at different times of the month, and that knowledge gives you power.

The menstrual cycle experience is ultimately brain-based. The brain is the control centre for how your body reacts to hormonal changes.

When you understand what’s happening in your brain during each phase, you can work with your cycle. That’s where real cycle mood regulation begins.

Why Your Mental Health Shifts Across Your Cycle

Your menstrual cycle follows a predictable hormonal pattern, and these hormones act as chemical messengers that profoundly affect brain function.

Estrogen rises during the follicular phase and tends to boost serotonin and dopamine, neurotransmitters that support mood stability and motivation.

After ovulation, progesterone takes centre stage during the luteal phase.

As both estrogen and progesterone drop sharply before menstruation, some women experience significant mood dips, brain fog, or emotional sensitivity.

These shifts cause noticeable mental health issues during PMS.

The key takeaway? Hormonal mood swings aren’t a character flaw. They’re neurological responses to predictable biochemical changes, and that means they can be managed with the right brain-first strategies.

8 Ways to Support Mental Health Across Your Menstrual Cycle

1. Track Your Patterns to Predict Your Needs

Understanding your unique cycle mood regulation patterns is the foundation of effective self-care. When you track symptoms across multiple cycles, patterns emerge that help you anticipate challenging phases and plan accordingly.

Record daily mood ratings, energy levels, anxiety or irritability, brain fog, and physical symptoms. After 2-3 cycles, you’ll likely spot trends. Maybe your anxiety peaks 5 days before your period, or brain fog hits mid-luteal phase.

The Samphire app acts as an active diary for your cycle, helping you spot when symptoms are likely, plan for focus days and rest days, and build habits around your natural rhythms.

2. Adjust Your Exercise Routine to Match Your Energy

Movement is one of the most powerful tools for mental health during PMS and beyond, but the type and intensity should shift with your cycle phases.

Follicular Phase (Days 1-14): As estrogen rises, try high-intensity interval training, strength training with heavier weights, or running.

Luteal Phase (Days 15-28): As progesterone dominates and energy dips, consider moderate cardio like walking or swimming, yoga, or lighter strength training.

Menstrual Phase (Days 1-5): Gentle movement like restorative yoga or walking can ease cramps and support mood without depleting energy.

Exercise stimulates endorphins and brain-derived neurotrophic factor (BDNF), both of which support neuroplasticity, or he brain’s ability to adapt. Research consistently shows that regular physical activity reduces symptoms of anxiety and depression.

3. Eat to Nourish Your Brain Chemistry

Your brain needs specific nutrients to manufacture neurotransmitters and regulate mood effectively. Hormonal mood swings can be amplified by nutritional deficiencies or blood sugar instability.

Nutrient

Brain Benefit

Food Sources

Omega-3 fatty acids

Reduces inflammation; supports serotonin

Salmon, walnuts, flaxseeds

Magnesium

Calms the nervous system; reduces PMS

Dark leafy greens, pumpkin seeds, dark chocolate

B vitamins (B6)

Essential for neurotransmitter production

Eggs, legumes, bananas

Complex carbs

Stabilises blood sugar; supports serotonin

Oats, quinoa, sweet potatoes

During the luteal phase, when serotonin naturally dips, eating complex carbohydrates can help maintain levels and reduce irritability. Avoid excessive caffeine and refined sugar, which can worsen anxiety and create energy crashes.

4. Prioritise Sleep Hygiene Throughout Your Cycle

Sleep disturbances are common across the menstrual cycle, particularly during the luteal phase. Poor sleep directly impacts mood regulation, making existing hormonal mood swings worse.

Sleep strategies for better cycle mood regulation:

  • Maintain consistent sleep and wake times
  • Cool your bedroom to 65-68°F, especially during the luteal phase
  • Limit screens 1-2 hours before bed
  • Create a wind-down routine with gentle stretching or meditation
  • Avoid caffeine after 2 PM

Research shows that sleep deprivation reduces activity in the prefrontal cortex while increasing amygdala reactivity, making you more emotionally reactive. Quality sleep gives your brain the resources it needs for effective cycle mental health care.

5. Practice Mindfulness and Stress Reduction Techniques

Chronic stress exacerbates mental health during PMS by dysregulating the hypothalamic-pituitary-adrenal axis, the same system that controls your menstrual cycle.

Mindfulness meditation increases grey matter in brain regions involved in emotional regulation. Just 10-20 minutes daily can reduce anxiety and improve your capacity to manage hormonal mood swings.

Evidence-based techniques to try:

  • Breath work: Box breathing (inhale for 4, hold for 4, exhale for 4, hold for 4) activates the parasympathetic nervous system
  • Body scan meditation: Systematically relaxing each part of your body reduces physical tension
  • Journaling: Writing about emotions helps process them and identify patterns
  • Progressive muscle relaxation: Tensing and releasing muscle groups calms the nervous system

6. Build Strong Social Connections

Social support isn’t just emotionally comforting. It’s neurologically protective. Strong relationships activate brain regions involved in reward processing and stress regulation, helping safeguard mental health during PMS.

During phases when you feel more withdrawn, maintain connection in manageable ways: texting a friend, attending a yoga class, or scheduling video calls during high-energy weeks.

Let trusted friends or partners know that your mood and social energy fluctuate with your cycle. Simply having someone understand why you need more space in certain weeks reduces guilt and anxiety.

7. Consider Cognitive Behavioural Strategies

Cognitive Behavioural Therapy (CBT) techniques are particularly effective for cycle mental health care because they help you identify and challenge thought patterns that worsen mood symptoms.

Simple CBT strategies for cycle mood regulation:

  1. Identify the thought: When you notice mood shifting, pause and ask, “What am I thinking right now?”
  2. Challenge the thought: Is there evidence for this thought? Am I jumping to conclusions?
  3. Replace with a balanced thought: “I feel irritable right now, and that’s normal for this phase of my cycle. This feeling will pass.”

This practice builds the prefrontal cortex’s capacity to regulate emotional responses, essentially training your brain for better emotional control.

8. Try Brain-Based Neuromodulation

Traditional approaches to cycle mood regulation typically focus on hormonal interventions or lifestyle changes alone. Samphire takes a different approach: targeting the brain directly using gentle neurostimulation.

Nettle™ uses transcranial direct current stimulation (tDCS), a non-invasive technology that delivers gentle electrical currents to specific brain regions involved in mood regulation and pain processing.

How brain-based solutions support mental health during PMS:

  • Hormone-free and drug-free: Nettle™ provides relief without altering your natural cycle
  • Clinically validated: Studies show that tDCS can reduce symptoms of anxiety, depression, and pain
  • Convenient: Just 20 minutes a day, 5 days per cycle, from home
  • Works with neuroplasticity: Repeated use helps retrain neural pathways for lasting improvements

When to Seek Professional Support

While these strategies can significantly improve mental health during PMS for many women, some symptoms warrant professional evaluation. Seek help if you experience severe mood symptoms interfering with daily life, thoughts of self-harm, or symptoms that don’t improve after 3 months.

Your Brain, Your Cycle, Your Control

Hormonal mood swings and mental health during PMS challenges aren’t weaknesses. They’re neurological responses to predictable biochemical changes.

When you understand what’s happening in your brain at each phase, you gain the power to support yourself effectively.

At Samphire, the focus is on the neuroscience of women’s health, because to truly understand and improve hormonal wellbeing, you need to start where hormones start: in the brain.

Samphire combines cutting-edge science with time-tested practices to deliver relief for women throughout the cycle.

Ready to experience brain-first cycle mood regulation?

Try Samphire Neuro Nettle™ risk-free with their 90-day trial and support your brain across every phase.

Insight

UK reviews surrogacy firm over rejected insurance claims

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The UK government is reviewing a surrogacy firm after complaints that medical insurance claims involving surrogates in Mexico were rejected.

The Department of Health and Social Care (DHSC) is considering whether UK-based provider My Surrogacy Journey should remain listed on gov.uk as one of four domestic surrogacy agencies available to intended parents.

The review follows allegations concerning its Mexican sister company, where surrogates are based.

Health minister Diana Johnson said: “The department is looking into the allegations about My Surrogacy Journey.

“As part of that assessment, the department will consider whether it is appropriate for that company to remain on the gov.uk list of agencies.”

Emails sent by My Surrogacy Journey chief executive Michael Johnson-Ellis and seen by the Guardian suggest multiple surrogate women in Mexico had their insurance claims rejected.

The emails also suggest 300 couples using the company were moved to a new insurance provider because of the increased risk of claims being rejected.

Commercial surrogacy is banned in the UK, where only altruistic arrangements are permitted.

My Surrogacy Journey operates a not-for-profit UK branch alongside for-profit sister companies in Mexico and the US. All three companies have the same owners and chief executives.

The reported insurance issues relate to surrogacy arrangements in Mexico.

One couple told the Guardian they paid tens of thousands of pounds to cover medical costs after their surrogate had a hysterectomy during childbirth and an insurance claim was refused.

The Guardian said it understood that at least five sets of parents said they had to cover medical costs after insurance claims were rejected.

In an email to the couple whose surrogate underwent a hysterectomy, Johnson-Ellis wrote: “We have already told you that the insurance companies have been declining some of the claims and we are actively working with the broker to get this issue resolved but you should also consider that they may not be paid out and there is nothing we are able to do to change this …

“We appreciate this is not an insignificant sum but this genuinely is out of our control.”

Johnson-Ellis also said the company had switched insurance providers, writing: “We’re also managing this for 300 other journeys, which is a complex position to be in.”

Lawyers acting for My Surrogacy Journey said the company did not comment on individual cases, but that existing insurance policies were in place and claims continued to be accepted and processed.

They said the company understood that a small number of claims had been rejected and was supporting people seeking to resolve those claims with an insurer.

Under the surrogacy arrangements, intended parents are understood to be contractually required to cover medical costs not paid by an insurer.

The couple said they had been recommended the company’s Mexico option. Its website advertises that intended parents using the route can have a baby in “under 18 months”.

They said they were told the UK route could take up to five years and that the US option was much more expensive.

Lawyers for My Surrogacy Journey said prospective parents are given information about typical timelines, costs, legal frameworks and practical considerations, and that the 18-month timeframe is indicative only.

The couple said their surrogate developed placenta accreta, a serious condition in which the placenta attaches to the wall of the uterus.

Emails from Johnson-Ellis acknowledged that the insurance provider investigated the birth after the surrogate experienced health complications.

The parents are considering legal action, while the Guardian said it understood at least four other couples were reviewing their options.

Phil Brickell, MP for Bolton West, raised concerns in parliament about a separate couple who had used My Surrogacy Journey.

He said: “Two of my constituents recently travelled to Mexico, where their children were born by surrogacy.

“Those births were facilitated by a company called My Surrogacy Journey, which is listed on gov.uk.

“While in Mexico, they had repeated traumatic experiences with the company relating to issues including insurance for their children, accusations of bullying towards staff and repeated efforts to silence any constructive criticism.

“I understand that other members of this house have received similar complaints.”

Brickell called for My Surrogacy Journey to be removed from gov.uk pending a review by the Human Fertilisation and Embryology Authority.

Lawyers acting for My Surrogacy Journey said the company was communicating with DHSC and was confident any issues could be resolved.

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‘Limited scientific evidence’ for most menopause supplements, expert says

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Many menopause supplements contain ingredients with limited evidence for symptom relief, while formulations and prices vary widely, a study has found.

Researchers analysed 201 products sold by nine major UK retailers, comparing their ingredients, doses and monthly costs.

Prices ranged from £1.50 to £95 a month, while no single ingredient or category of ingredient was common across all products.

The study, carried out by University College London, found that 80 per cent of products contained herbs, 77 per cent contained vitamins and 74 per cent contained phytoestrogens, naturally occurring plant compounds found in foods including soy and flaxseed.

Vitamin B6 was the most common vitamin, while red clover and sage were the most frequently identified plant ingredients.

Researchers said more evidence was needed on the effectiveness and safety of supplements marketed for menopause symptoms.

Professor Joyce Harper, senior author of the study and professor of reproductive science at University College London, said: “The menopause supplement market is growing rapidly, despite limited scientific evidence that many of these products improve menopause symptoms.

“Some social media influencers promote these products as effective solutions, despite many claims not being supported by scientific evidence.

“This can contribute to the spread of misinformation and help drive a rapidly growing menopause supplement market, leading some women to spend substantial amounts of money on supplements in the hope of improving their symptoms and overall wellbeing.”

Half of the supplements did not contain vitamin D, while less than 24 per cent contained calcium.

The British Menopause Society and International Menopause Society have highlighted vitamin D and calcium as important for maintaining bone health and preventing osteoporosis after menopause.

Researchers also identified botanical ingredients that may carry risks, including black cohosh.

Poppy Sullivan, first author of the study, said: “Certain botanical ingredients in some menopause supplements may also have risks.

“Black cohosh, in particular, is known to carry a potential risk of liver toxicity.”

The amounts of vitamins and minerals included in different products also varied widely.

Sullivan said: “Some nutrients can have adverse effects when consumed in excess over time.

“For example, excessive vitamin D intake can theoretically lead to high calcium levels, which could cause adverse effects such as vomiting and confusion.”

The study found little empirical evidence supporting the effectiveness of even the most expensive products.

Researchers called for more high-quality research, including clinical trials, to determine whether menopause supplement ingredients are effective and safe.

They said the findings could also help healthcare professionals understand the wide variation in supplement formulations.

The researchers acknowledged that the analysis may not have included every menopause supplement available in the UK.

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Ultrasound Direct extends Trice Imaging partnership

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Ultrasound Direct has extended its Trice Imaging partnership for three years, adding a reporting tool across its 70-clinic UK network.

The private ultrasound provider will continue using the Tricefy platform for secure image storage and patient engagement, alongside TriceIQ for efficiency and productivity analytics.

It will also introduce Trice Workspace Reporting across its network. The companies say the tool will help standardise ultrasound reporting templates and workflows and reduce variation between clinics.

Ultrasound Direct carries out an estimated 120,000 patient scans each year across services including pregnancy, fertility, women’s health, men’s health and other diagnostic pathways.

Its network uses a large pool of sonographers working across different ultrasound systems and serves referral routes including self-referring patients, GPs and commercial partners.

Mike Steward, founding director at Ultrasound Direct, said: “Having worked with Trice Imaging since 2018, we first partnered to replace manual methods of providing scan images to expectant parents with Trice’s secure electronic image-sharing platform. Today, every study performed across the Ultrasound Direct Network is recorded and stored on Tricefy, while our clinical services have expanded considerably beyond pregnancy into fertility, women’s health, men’s health and other diagnostic pathways.”

He added: “To continue futureproofing our image management strategy across a network of 70 clinics, a large team of sonographers, varying ultrasound systems and a growing number of referral partners with different needs, we decided to extend with Trice Imaging. This includes the introduction of the new Trice Workspace Reporting module to help us scale and standardise our ultrasound reporting templates and workflow, reducing variability between clinics.”

The partnership began in 2018, initially focusing on replacing manual methods of sharing pregnancy scan images with expectant parents.

Johanna Wollert Melin, founder and chief executive of Trice Imaging Europe, said: “Ultrasound Direct has been a valued partner in the UK for 8 years.”

She added: “At the heart of the relationship is a willingness to explore new ideas, test new tools and the spirit to solve real challenges across a large and complex clinical network.”

Mark A. Samii, chief revenue officer at Trice Imaging, said: “We are delighted to retain and extend our relationship with Ultrasound Direct.”

He added: “The addition of Trice Workspace Reporting addresses a challenge we hear from multi-site providers globally – keeping reporting quality consistent across many users, systems, referral or payer relationships.”

Steward said Ultrasound Direct continues to see growing demand for private diagnostics alongside NHS care from self-referring patients and an increasingly diverse range of professional and commercial referral partners.

He added: “As that development continues, scalable digital infrastructure becomes increasingly important. Our focus is on ensuring that a growing national network can support consistent clinical workflows, different referral pathways and the technology requirements of the future, while continuing to provide patients with accessible diagnostic services.”

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