Special
Everything you need to know about fibroids

Fibroids, non-cancerous growths that develop in or around the womb, are the most common tumours in women worldwide. Here, we look at everything you need to know about them.
What are fibroids?
Fibroids are non-cancerous growths that develop in or around the womb. They often appear during the fertile years and they are also known as uterine myomas or leiomyomas.
Fibroids vary in number and size. You can have a single fibroid or more than one. Some of these growths are too small to see with the eyes. Others can grow to the size of a grapefruit or larger.
A fibroid that gets very big can distort the inside and the outside of the uterus. In extreme cases, some fibroids grow large enough to fill the pelvis or stomach area.
Many women are unaware they have fibroids as they do not have any symptoms.
What are the symptoms?
Around one in three women with fibroids may experience:
- heavy periods or painful periods
- abdominal pain
- lower back pain
- a frequent need to urinate
- constipation
- pain or discomfort during sex
In rare cases, further complications caused by fibroids can affect pregnancy or cause infertility.
Why do fibroids develop?
The exact cause of fibroids is unknown, but they have been linked to the hormone oestrogen. Fibroids usually develop during a woman’s reproductive years when oestrogen levels are at their highest.
They tend to shrink when oestrogen levels are low, such as after the menopause, when a woman’s monthly period stops.
Who gets fibroids?
Fibroids are common, with around one in three women in the UK developing them at some point in their life. They most often occur in women aged 30 to 50.
They are thought to develop more often in women of African-Caribbean origin. It’s also thought they occur more often in women who are overweight because being overweight increases the level of oestrogen in the body.
Women who have had children have a lower risk of developing fibroids.
How are fibroids treated?
Fibroids do not need to be treated if they are not causing symptoms. After the menopause, they will often shrink without treatment.
If you do have symptoms caused by fibroids, the NHS recommends medicine to help relieve the symptoms first.
There are also medications available to help shrink fibroids. If these prove ineffective, surgery or other, less invasive procedures may be recommended.
When should I see a doctor?
See your doctor if you have:
- Pelvic pain that does not go away
- Heavy or painful periods that limit what you can do
- Spotting or bleeding between periods
- Trouble emptying your bladder
- Ongoing tiredness and weakness, which can be symptoms of anemia
Get medical care right away if you experience severe bleeding or sharp pelvic pain.
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Special
Jill Biden visits Imperial on women’s health and AMR mission

Former US first lady Dr Jill Biden visited Imperial College Healthcare NHS Trust and Imperial College London to explore work on women’s health and antimicrobial resistance.
The visit was hosted by professor the Lord Darzi of Denham, who chairs the Fleming Initiative and directs Imperial’s Institute of Global Health Innovation.
Dr Biden, chair of the Milken Institute’s Women’s Health Network, spoke about the impact scientists, clinicians, innovators and investors can have on improving women’s healthcare.
Dr Biden stressed the importance of “collaboration, prevention and education” in improving women’s health globally.
At the museum, Dr Biden and Esther Krofah, executive vice-president of health at the Milken Institute, heard about the worldwide significance of the discovery and the contribution of women who, during wartime Britain, grew penicillin in bedpans to support early experimentation.
The discussion also explored how AMR is a key women’s health issue, with women disproportionately affected in low and middle-income countries, and in high-income settings where women are more likely than men to be prescribed antibiotics.
Dr Biden was shown an architectural model of the Fleming Centre in Paddington, which will bring together research, policy and public engagement to address AMR worldwide.
The second part of the visit brought together Imperial clinicians, researchers and innovators for a roundtable on women’s health priorities, including improving diagnosis, equity in maternity care and support during the menopause transition.
Participants highlighted wide variation in the quality of care for conditions affecting women and called for fairer access to services, with the postcode lottery named as a priority to address.
Professor Tom Bourne, consultant gynaecologist and chair in gynaecology at Imperial’s Department of Metabolism, Digestion and Reproduction, described how AI could improve diagnostic accuracy for conditions such as endometriosis.
Equity emerged as a central theme.
Professor Alison Holmes, professor of infectious diseases at Imperial College London and director of the Fleming Initiative, highlighted persistent gaps in women’s representation in clinical trials, including antibiotic studies, which limits the ability to optimise care and treatments.
Dr Christine Ekechi, consultant obstetrician and gynaecologist at Imperial College Healthcare NHS Trust, drew on national maternity investigations to underline the importance of valid data, meaningful engagement with affected communities and rebuilding trust.
Menopause and midlife health were also identified as priorities for clinical research.
Professor Waljit Dhillo, consultant endocrinologist and professor of endocrinology and metabolism in Imperial’s Department of Metabolism, Digestion and Reproduction, described a new treatment for hot flushes, including for women unable to take hormone replacement therapy, such as those with a history of breast cancer.
The discussion then turned to bringing innovation into health systems. Innovators shared how data and technology are being used to close gaps in women’s health, while noting challenges in accessing funding to grow and scale.
Dr Helen O’Neill and Dr Deidre O’Neill, co-founders of Hertility Health, described predictive algorithms using self-reported data to help diagnose gynaecological conditions at scale.
Embedded into clinical workflows, the technology could reduce waiting times, identify conditions earlier and improve outcomes. They noted how “we have cures for the rarest genetic conditions but don’t even have the answers to common women’s health issues.”
Dr Lydia Mapstone, Dr Tara O’Driscoll and Dr Sioned Jones, co-founders of BoobyBiome, outlined work creating products that harness beneficial bacteria found in breast milk to support infant health.
By isolating and characterising key microbial strains, BoobyBiome has created synbiotics, combinations of beneficial bacteria and the food that nourishes them, to make these benefits accessible to all babies.
Speakers throughout the visit stressed the need to reduce variation in care quality and outcomes for women, strengthen prevention and education, and address power and equity in women’s health.
Professor the Lord Ara Darzi said: “It was a privilege to welcome Dr Biden and the Milken Institute to Imperial to meet some of the outstanding researchers, clinicians and innovators advancing women’s health.
“Imperial’s unique combination of clinical excellence and world-leading research positions us at the forefront of tackling the biggest health challenges facing society and the UK’s ambition for innovation demands nothing less.
“For too long, the health needs of women and girls across their life course have not received the attention they deserve.
“By working together across borders and disciplines, we can transform equitable access to care, accelerate the detection and treatment of disease, and ultimately improve health outcomes for millions of women in the UK and around the world.”
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