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Hormonal health

Mira launches tool to predict menopause and monitor fertility

The tool measures hormone levels at home without the need for a blood test

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The US Food and Drug Administration (FDA) has approved Mira’s new hormone tracker as an over-the-counter tool to predict menopause and evaluate fertility.

The Ovum Wand is an AI-powered device that provides accurate detection of the follicle-stimulating hormone (FSH) in urine to help monitor fertility and find possible causes of reproductive issues for women after 35.

From October, the product will be available to US customers. The tool aims to help women get an inside look into their full menstrual cycle, manage irregular cycles, PCOS, and hormone imbalances as well as monitor hormone levels for fertility treatments such as IVF and IUI.

Menopause has been a taboo subject for many generations. Studies have shown that one third of women do not research the topic before they experience menopause.

A survey of 1,039 American women aged 40-65 has found that 45 per cent did not know the distinction between perimenopause and menopause.

Mira, a mobile health platform for monitoring reproductive health, is hoping that its Ovum Wand will provide information to help women understand these life stages and address the symptoms early.

Tracking the FSH is essential for women in their 20s, 30s, or 40s because it directly impacts their ability to get pregnant. To predict approaching menopause or track changes in fertility, a person needs to test over several days for two or more cycles.

Additionally, FSH tracking could also help monitor the effectiveness of hormone replacement therapy (HRT) to make it more targeted and personalised.

Mira allows users to safely monitor their FSH levels at home without the need for a blood test. Data points are saved and analysed to give personalised health insights and the users can also share the information with their medical provider.

“The Mira Ovum Wand further expands our capabilities in at-home hormone testing,” says Sylvia Kang, Mira CEO. “The launch reinforces Mira’s goal to support women throughout their lives by helping them understand their hormones at any age, be it puberty, adulthood, or later years.”

She adds: “This knowledge grants the ability to make informed fertility decisions and eliminates the dread associated with the word ‘menopause’, so that women can go through this journey with confidence and awareness.”

The company offers a line of hormone test wands. Like its predecessors, the new Ovum Wand is compatible with the Mira’s analyser and uses machine learning to track changing hormone patterns over time. The analyser can be connected to Mira App to display clear numerical data along with personalised insights on the user’s reproductive health.

For more info, visit miracare.com.

Hormonal health

Man City launch female athlete health education platform

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Manchester City has launched a female athlete health platform covering menstrual, pelvic and breast health, as well as nutrition.

The Her City website is designed for the club’s women’s first-team players, coaches, support staff, academy players and parents.

Manchester City says the platform is the first of its kind in the Women’s Super League and was developed over two years.

The project was led by director of performance services Emma Deakin, physical performance scientist Rosie Anderson and PhD student and first-team nutritionist Sarah Malone.

It grew out of PhD research into menstrual, pelvic and breast health and nutrition, with the team seeking to turn that work into an online educational resource.

The website divides the four areas into separate sections and provides peer-reviewed information that the club says has been critically analysed by experts.

Content will continue to be reviewed and updated as further evidence emerges.

Resources include posters, visual explainers, audio materials and downloadable educational content, with information tailored to different groups including players and parents.

The platform aims to improve knowledge, develop critical analysis skills and strengthen communication within football and at home.

It also includes material to help users assess misinformation they encounter on social media or elsewhere.

A confidential contact form allows users to raise concerns or ask questions directly of experts at Manchester City.

Parents of academy players can also access the platform, with resources intended to help them support their children during a key phase of their development.

Manchester City said its longer-term aim is to make the platform available to all women working across City Football Group.

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Menopause

NIH awards multi-university team over US$4 million to improve women’s health

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Michigan State University researchers are launching a novel project to transform how medications are developed and prescribed for women.

A US$4.6m award will fund computer models designed to predict how hormonal changes affect the way medicines move through and act in women’s bodies.

The funding is the first instalment of an award worth up to US$12.8m over three years, supporting work intended to account for hormonal changes throughout women’s lives.

Researchers plan to examine factors including menstrual cycles, pregnancy, contraceptive use, menopause and hormone replacement therapy, which can affect responses to medicines.

Teresa K. Woodruff, lead investigator on the project, said: “Because female hormone levels are constantly shifting, precision medicine allows us to map out these complex interactions.

“This NIH-backed initiative will create the first computationally driven clinical tool designed to guide medical care across every stage of a woman’s life.”

The project is led by researchers at Michigan State University and funded by the National Institutes of Health, with collaborators from Rutgers, Emory, Tulane, the University of Colorado Anschutz, the University of Michigan and the University of Utah.

Thirteen researchers will develop computational models to predict how changes in female hormones influence the way medicines move through and act within the body.

The work is part of the NIH Computational Modeling of Hormone Homeostasis Initiative, which is awarding US$21m nationally to support research into sex-specific hormonal biology.

The team plans to use artificial intelligence to digitise and organise more than 40 years of hormone research data in a publicly accessible database.

Researchers will also develop a standard computer model of a 28-day menstrual cycle, alongside models of how hormones regulate organs and tissues involved in processing nutrients, including the liver, muscle and fat.

Real-world patient data will then be used to expand the models to represent groups including women going through menopause or taking birth control, as well as women with conditions such as diabetes and obesity.

The project will also use three-dimensional human tissue models and lab-grown organoids, including liver, muscle and ovarian tissue, to test and refine the computer predictions.

Researchers plan to examine medicines including metformin, insulin and GLP-1 drugs, with the aim of developing tools that could help clinicians tailor doses and avoid harmful side effects.

Qiang Zhang, associate professor at Emory University, said: “Empowered by AI, novel assays and legacy human data, we will develop mechanistically based computational models of female physiology that can make translational, quantitative predictions for women’s responses to metabolic therapies.”

The researchers said the work could help address differences in how women respond to treatments for metabolic conditions including obesity, type 2 diabetes, cholesterol imbalances and thyroid disorders.

Nanette Santoro, professor at the University of Colorado Anschutz and president of the Endocrine Society, said: “Women experience large shifts in reproductive hormones at several points in their lifespan: puberty, pregnancy and menopause.

“During reproductive years, women also undergo profound day-to-day changes in reproductive hormone levels, giving them a markedly different endocrine backdrop than men.

“Using state-of-the-art computational technology to examine how these changes interact with commonly used medications is a critical pathway toward supporting life-course women’s health.”

The project team said its computer models and data will be made freely available to researchers and healthcare professionals when the work is completed.

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Menopause

High street bakery chain Gail’s reveals menopause plan

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Gail’s has unveiled a menopause action plan offering new workplace support to thousands of staff ahead of legal reforms due in 2027.

The high street bakery chain will offer new benefits including 24/7 digital GP access and a new employee assistance programme, according to The Times.

It will also explore new online training for staff, including specific training for management.

Gail’s people director Miranda Burgum told The Times: “All we’re trying to do is talk freely and for it not to be a forbidden subject. It’s helping our managers and teams understand that this isn’t a taboo.”

“We’re going to develop the education with our managers, so it will be threaded through all our policies

“It will look at induction training, it will look at the types of people we need to make sure that we make reasonable adjustments for.

“And if somebody needs some sort of risk assessment, we’re going to be looking at [that].”

The move comes ahead of reforms due to be introduced in spring 2027 under the Employment Rights Act.

UK employers with 250 or more employees will be legally required to publish and update official menopause action plans.

The plans are intended to support employers to take effective action to improve workplace gender equality and support employees experiencing menopause.

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