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Swedish femtech start-up to join acceleration programme in Copenhagen

BioInnovation Institute’s Venture Lab programme aims to support early-stage start-ups within human and planetary health

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BioInnovation Institute/Esben Zøllner

Swedish start-up Pharmista Technologies, a participant in SmiLe’s incubator programme, is to join the Venture Lab programme in Copenhagen.

The one-year programme, designed by the BioInnovation Institute, aims to support early-stage companies in business development, scientific advancement and team development. Membership also includes financial support in terms of a convertible loan of €500,000.

Focusing on women’s health and sustainability, Pharmista is developing a reusable pregnancy test for home use. The company’s goal is to have a prototype ready by the end of the programme that can be reused at least ten times with high accuracy.

“Being part of Venture Lab means that we will have access to the BioInnovation Institute’s mentorship programme, their facilities in Copenhagen and their extensive network,” explained Alice Mattsson, Pharmista founder and CEO.

“In addition, we finally have the funding to accelerate the development of our technology and product. We are very excited about what this year has to offer.”

Johanna Roostalu, director of women’s health at BioInnovation Institute, said: “Pharmista Technologies is developing an exciting new solution within the women’s health space, and we are thrilled to support them through our Venture Lab programme.

“Besides having a commercially interesting and impactful case, they also have a great team which is fundamental when you are an early-stage start-up.”

Ulrika Ringdahl, COO of SmiLe Incubator, added: “We are very happy and proud that one of our incubator companies has been selected to participate in BII’s Venture Lab programme.

“Our task is to support our companies in every way possible to help them succeed. It is very positive that Alice Mattsson now gets access to an expanded network and an opportunity to further develop the product and the company.”

The BioInnovation Institute is a non-profit foundation financed primarily by the Novo Nordisk Foundation.

Through its Venture Lab programme, the organisation seeks to support companies within planetary health/bioindustrials, health tech, therapeutics and women’s health.

After completing the programme, companies can apply to join the BioInnovation Institute’s Venture House programme and receive an additional €1.3m in funding.

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Menopause

Xella Health announces Oura data integration

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Xella Health has integrated Oura wearable data into its women’s health platform, allowing members to share trends with clinicians alongside diagnostic results.

Members can choose to share information including sleep, heart rate variability, resting heart rate, temperature trends, recovery, activity and menstrual-cycle data.

The integration is intended to help clinicians investigate biological factors that may explain changes in members’ wearable data and symptoms.

Kelly Lacob, chief executive and co-founder of Xella Health, said: “Wearables detect that something in the body has changed, but wearable data alone can’t tell a woman why or what to do next with that information.”

“By pairing continuous physiological monitoring from Oura with Xella’s multiomic diagnostics and physician-guided care, we enable women to understand how specific health concerns are impacting her biometrics, and vice versa how her daily habits are impacting her overall health and specific conditions or life stages she is navigating.

“Further, we are able to track how her relevant vitals and biometrics respond to specific interventions or treatment plans, so we can optimise her care more efficiently.

“Ultimately, this partnership helps us better address her symptoms today whilst also proactively optimising her long-term health trajectory for decades to come.”

Xella Health combines AI, multiomic testing and physician-guided telehealth care through a membership platform.

Multiomic testing analyses several types of biological information.

Xella said its testing assesses hormonal and metabolic health, inflammation, nutritional status, reproductive health and cardiometabolic risk.

Physicians use those findings to develop personalised care plans that may include clinical treatments.

Clinicians can then review shared Oura trends alongside diagnostic results and member check-ins to monitor progress and adjust care over time.

The company said providers interpret biometric data in the context of each member’s health conditions, goals and treatment plan.

The integration focuses on fertility, perimenopause, hormonal and cardiometabolic health, as well as women’s longer-term health.

Oura has expanded its women’s health offerings through integrations connecting wearable measurements with other sources of health data.

In February, it partnered with at-home hormone tracking company Mira, allowing users to view hormone test results alongside sleep, temperature and readiness data in the Mira app.

The integration is intended to help users track patterns related to fertility, menstrual cycles and perimenopause.

That month, Oura also introduced a women’s health AI model for testing through Oura Labs.

Integrated into Oura Advisor, the model combines biometric data with clinician-reviewed medical information to provide guidance on menstrual cycles, pregnancy and menopause.

In May, the company launched menopause insights and hormonal birth control support.

Its Menopause Insights offering uses a questionnaire covering 22 symptoms of menopause alongside wearable data, while birth control support helps users understand their biometric trends in the context of hormonal contraception.

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Menopause

Tech enables men to experience what a hot flush feels like

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Partners of women going through menopause will be invited to experience hot flushes using a menopause simulator at a support event in Hull next month.

Health group Over The Bloody Moon will bring one of its MenoVests to the Menopaus’ull Support Network event, allowing people to experience a hot flush.

Sarah Weichardt, who co-manages the project, said: “We’re particularly interested in getting men along to come and experience the MenoVest, just so that they can understand what women go through.

“It’s not just a hot flush, it’s what the hot flush brings with it.

“So it could be panic, it could be anxiety. It’s experiencing it all at the same time.”

MenoVest is billed as the ‘world’s first’ wearable menopause simulator – a garment worn over regular clothing that generates realistic, intense hot flush sensations while the wearer carries on with everyday work tasks.

After just a few minutes wearing it, people gain a genuine sense of what these symptoms feel like, building empathy and highlighting why better support matters during this transition.

Weichardt said she hoped the vest would give people a “better understanding of what women are going through”.

“The more people we can get to experience it, the better,” she added.

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Menopause

Short term HRT may raise blood clot risk – study

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Short-term oral HRT was linked to a 60 per cent higher rate of serious blood clots in women aged 50 to 69, a large study found.

The increased rate was seen among women using oral hormone replacement therapy for less than a year as well as those treated for more than five years.

By contrast, transdermal HRT, delivered through skin patches, gels or sprays, was not associated with the same increased clot risk.

Researchers at North Zealand Hospital in Denmark analysed health registry data from more than one million Danish women aged 50 to 69 between 2003 and 2021.

During the study period, 9,807 women experienced venous thromboembolism, a serious blood clot in a vein. A further 18,460 had a stroke and 11,974 had a heart attack.

Each affected woman was matched by age with five women who had not experienced the same condition. Researchers adjusted the analysis for other factors, including medical history, that could influence risk.

They then examined HRT prescriptions, including the dose and duration of treatment, and looked for associations with blood clots, stroke and heart attack.

Overall, oral HRT was associated with a 60 per cent higher rate of venous thromboembolism, with increased rates seen for both oestrogen-only therapy and treatment combining oestrogen with progestogen.

Venous thromboembolism occurs when a blood clot forms in a vein. A clot in a deep vein can break away and travel to the lungs, causing a potentially fatal pulmonary embolism.

Women taking oral HRT for less than a year had the same raised blood clot risk as those using it for more than five years.

Even a daily oral dose below 1mg was found to significantly increase blood clot risk.

Women taking a daily oral dose above 1mg for more than five years had an 80 per cent higher risk of both heart attack and stroke.

For women taking a high oral dose for more than one year, the study found a 40 per cent higher risk of heart attack and a 50 per cent higher risk of stroke.

The researchers highlighted the importance of choosing the type, dose and duration of treatment carefully, particularly for patients vulnerable to blood clots.

Dr Robert Storey, professor of cardiology at the University of Sheffield, who was not involved in the research, said the findings demonstrated the importance of ensuring cardiovascular risk factors were “well controlled” in women taking oral HRT.

He added: “The study emphasises the superior safety of patches over oral treatment.”

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