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WOMEN’S HEALTHY AGING INNOVATION SUMMIT

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Kisaco Research

WOMEN’S HEALTHY AGING INNOVATION SUMMIT

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The Women’s Healthy Aging Innovation Summit is the leading industry platform that connects pharma, biotech, start-ups, investors, payers, researchers, FMCGs and HCPs to accelerate innovation, investment, research, and partnerships to improve health outcomes for midlife women and beyond.

Addressing the entire spectrum of this underserved area, the Women’s Healthy Aging Innovation Summit stimulates discussions around the opportunities and challenges in areas relating to menopause, longevity, osteoporosis, cardiovascular health, sexual wellness, pelvic floor health, brain health, and preventative health measures.

Join us in 2023 as we expand these conversations and continue to serve the unmet needs of midlife women to improve outcomes.

To register for this event please visit the following URL: https://www.kisacoresearch.com/events/womens-healthy-aging-innovation-summit →

 

Date And Time

2023-12-06 to
2023-12-07
 

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Sorina Mihaila is the editor of Femtech World. Sorina covers technology, research and innovation in women's health.

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From PCOS to thyroid troubles- an exploration of women’s hormones

By Dr Haleema Sheikh, specialist in integrative women’s health and bioidentical hormone balancing for the Marion Gluck Clinic

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Dr Haleema Sheikh, specialist in integrative women's health and bioidentical hormone balancing for the Marion Gluck Clinic

Hormones are our bodies’ communication messengers.

They are chemicals that are released by one organ/tissue that are carried in the blood and impact another organ/tissue and thus coordinate different functions in our body.

These signals tell your body what to do and when to do it and cause significant issues when there is hormonal imbalance.

Hormonal balance is very often related to our lifestyle. The environment we bathe our genes in impacts which genes are switched on and off.

Our body is always trying to be balanced and so our hormones adapt to try to create balance within the body and are a reflection of environmental and mental inputs.

Unlike men who have a 24hr testosterone cycle with testosterone peaking in the morning, the female menstrual cycle requires a complex dance of hormones to interplay to release an egg monthly.

This includes building up the lining of the womb in preparation for a fertilised egg and if there is no pregnancy to allow the lining to break down and start the whole process again.

This roughly 28-day cycle can be easily unbalanced by a number of factors, including poor nutrition, suboptimal movement, disturbed sleep, excess stress, poor relationships and high toxic burden from environmental toxins.

Reproductive hormonal symptoms can show up in a variety of ways including painful and/or heavy periods, infertility, altered cycle and PMS.

PCOS is a common (one in five to 10 women) but often poorly understood whole body hormonal/metabolic disorder that affects women of reproductive age.

The defining feature of PCOS is irregular/anovulatory cycles and the over-production of male type hormones- androgens. The increased androgens can lead to acne, oily skin and hirsutism.

Many women with PCOS also struggle with weight gain, particularly in the abdominal area.

The irregular cycles can interfere with getting pregnant and so balancing the hormones is key to restoring fertility.

There are genetic predispositions for PCOS which had a survival advantage in the past when food was scarce, and we had to fight predators.

It has been said that women with PCOS have the genes of warrior princesses and this is why it has perpetuated.

Women with this condition are struggling in today’s modern society because we are often sitting at work for hours at a time and then sitting in front of screens in the evening.

Our genes expect movement in the day and to follow natural rhythms and the sedentary nature of modern day life results in a mismatch and health issues.

The name arises from the multiple follicles seen on ultrasound of affected women- these are not true cysts.

Many young women will have these appearances and should not be automatically diagnosed with PCOS unless they have the androgen excess symptoms and irregular periods.

Women suffering from PCOS have hormonal imbalance that has a few root causes including blood sugar regulation (insulin resistance), inflammation and poor gut health. Addressing these areas is foundational to managing and reversing PCOS symptoms.

The conventional medical model is focussed on managing symptoms of PCOS and will often result in putting women on the pill to regulate periods and reduce androgen symptoms, but this is not dealing with the root cause and bringing the body back into balance.

When women have difficulty getting pregnant, they are given drugs to try to induce ovulation or referred for IVF. These are useful options to explore when lifestyle interventions have not been fruitful and should remain a reserve option.

The functional medicine approach to PCOS focuses on:

  1. Optimising diet to improve insulin sensitivity through encouraging low-carb nutrition which helps improve insulin resistance a cornerstone driver of the condition.
  2. Supporting gut health to reduce inflammation which is another key factor. Pre and probiotics can support the gut microbiome which modulate hormone balance and detoxification.
  3. Reducing exposed to toxic ‘endocrine disrupters’ in the environment like BPA in plastics because they’ve been shown to disrupt the hormonal system by altering the way in which hormones interact with their receptors and how they are used/ metabolised within the body. Thesexenoestrogens can be found in plastic bottles/containers and in many skincare products/makeup which get absorbed through the skin so it is important to use ‘clean’ products and work on minimising exposure.
  4. Minimising stress through lifestyle tweaks like meditation and yoga which help support the parasympathetic rest and digest nervous system.
  5. Using targeted supplements and herbs to support hormones further, including magnesium, which improves insulin sensitivity and is anti-inflammatory, omega 3 fatty acids, inositol and zinc.

We can also use natural bioidentical progesterone to help women with PCOS kick start a regular ovulatory cycle.

Progesterone is released in the second half of the cycle after ovulation.

Professor Jerilyn Prior has been a pioneer in her work on the use of cyclical natural progesterone for two weeks on and two weeks off to help trigger ovulation in women who are not ovulating, and this helps correct the hormonal imbalance. This can fully explored in a bioidentical hormone clinic.

Thus, in the example of PCOS we can see the far-reaching, whole-body consequences of reproductive hormone balance.

Interestingly, women are also five to eight times more likely than men to have thyroid hormone problems, with one in eight women developing a thyroid disorder during her lifetime.

The thyroid is a butterfly-shaped gland at the base of the neck that produces hormones (thyroxine) essential for regulating metabolism, body temperature, energy, heart rate, menstrual cycle, mood, and hair and nail growth.

Essentially, it serves as the body’s thermostat controlling how fast things happen in the body by its actions on different organs/tissues.

There are two main categories of thyroid problems hypothyroidism (an under-active thyroid) and hyperthyroidism (an overactive thyroid).

In the case of hypothyroidism, the body literally slows down and causes symptoms like weight gain, brain fog, constipation and sluggishness.

The thyroid is not producing enough of the thyroid hormones – triiodothyronine T3 (active form) orthyroxine T4 or both.

The thyroid is a sentinel gland assessing the environment and ensuring the body adapts appropriately.  It requires a number of nutrients to function optimally and lack of these can cause it to under function. These nutrients include selenium, zinc, vitamin A, iron and iodine.

Reversing these deficiencies can help the thyroid improve its functioning.

In addition, the immune system can become muddled and produce autoantibodies which mark the thyroid for destruction by the white cells of the immune system. This is called Hashimoto’s disease an autoimmune condition which is more common amongst women.

There is a triad of genetic predisposition, increased gut wall permeability which allows the immune system to be more activated and a trigger e.g. stress/gluten exposure which ignites the whole process resulting in the production of antibodies which label the thyroid as foreign and for attack.

The conventional medical model works on trying to reduce the symptoms of hypothyroidism by giving replacement thyroxine support.

This can help the situation but does not address the immune activations and high levels of antibodies causing the thyroid to be attacked. Patients will feel a bit better, but it certainly does not bring vitality and full wellbeing to the majority.

In the functional medicine world patients are often given replacement hormone but there will also be emphasis on addressing the root cause by:

  1. Improving gut health and reducing gut permeability. This requires working on the gut microbiome and nutrition. 85 per cent of patients with Hashimoto’s do better on a gluten-free diet because there is molecular mimicry between the gluten molecule and the thyroid and in individuals with a genetic predisposition the immune system reaction against gluten ingested can also target thyroid tissue.
  2. Working on the other pillars of health sleep, relaxation and movement can also help bring the body back into balance and help the immune activation.
  3. Ensuring there are not nutritional deficiencies impacting the gland.

Women in the perimenopause and menopause are more at risk of thyroid disorders as there are oestrogen receptors on the thyroid and at this time there is hormonal fluctuations which can trigger thyroid dysfunction.

During the menopause, as a result of the lack of estrogen, thyroid function can be suboptimal and this can contribute to the menopausal weight gain around the middle that happens and the deterioration in lipid panels.

We can see how endocrine glands interact with each other; the body has a complex web of interconnection which help keep the body in balance.

When we are seeing hormonal dysfunction symptoms is important not only to look at symptoms control but to look at deeper root causes driving the issues.

Careful consideration to the environment we are bathing our genes is key to optimal hormonal health and this is best done with a medical professional who understands the importance of hormonal health.

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The vital role of AI skills in women’s career advancement and practical steps to begin

By: Chaitra Vedullapalli, Co-Founder & President of Women in Cloud

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With the unparalleled level of noise, confusion, and fear surrounding AI it can become overwhelming to parse out what news is sensationalised and what is true, especially when it comes to AI and the impact it has on the jobs market. 

Contrary to what some fear-mongering articles have shared, according to the 2024 Work Trend Index from Microsoft and LinkedIn, tech leaders are worried about whether or not they will be able to fill key roles. 

Over the past eight years companies have hired up to 323 per cent of technical AI talent.

Now they’re turning their sights to non-technical talent with AI aptitude. This means they’re actively seeking new team members with the skills to use generative AI tools like ChatGPT and Copilot. 

As the founder of an organisation committed to generating $1B in new economic access for women and allies in tech by 2030, I can see a huge opportunity for diverse women and allies in tech to land new roles and as a result speed up the closure of the representation and gender gap.

How?

By actively preparing, pursuing and learning new skill sets and earning the credentials to prove it. 

To get ahead of this anticipated hiring wave, here are three reasons to pursue certifications and credentials for real-world skill sets that address critical business problems right now:

  1. Career Advancement in an AI-centric Economy: By gaining relevant project-based, you will enhance your confidence and increase your trust level with current managers as well as hiring managers. In an AI-driven economy, possessing AI skills becomes imperative for career progression. Investing time in developing these skill sets now ensures you are well-positioned to seize opportunities and contribute meaningfully to any organisation’s growth.
  2. Future-proofing Skillsets for AI Opportunities: Investing in AI skills today equips you with future-proof capabilities essential for navigating the evolving job market. By seizing AI opportunities now, individuals ensure they stay ahead of the curve and remain adaptable and competitive in an AI-driven environment.
  3. Accelerated Skill Development and Enhanced Professional Profile: Pursuing scenario-focused credentials enables individuals to achieve credentials faster, accelerating their skill development journey. By showcasing project-based proficiency, individuals will differentiate themselves and demonstrate their ability to apply theoretical knowledge to real-world situations. 

Rather than staying stuck in fear of how AI may change the jobs landscape, women everywhere need to reframe this shift as an invitation to enter tech for the first time or scale to a new role they’ve been aiming for. 

It’s no secret that the entry barrier for diverse and underrepresented communities in tech is often much greater than not.

However, one of the most overlooked and underutilised ways to mitigate this is obtaining certifications and verifiable credentials for skillsets companies will have as requirements when hiring for new roles. 

A great place to start your journey is with the #WICxSkillsReadyChallenge.

This initiative leverages Microsoft Applied Skills, offering a new verifiable credential that validates specific real-world skill sets that address critical business problems.

This new skill set can be earned through interactive lab-based assessments on the Microsoft Learn platform in weeks.

During this challenge participants will earn Microsoft Applied Skills credentials in AI in just weeks, have the opportunity to win exciting prizes every month, receive exclusive invitations for spotlights, speak at events, network with recruiters, and connect and become a part of the record-setting WIC community.

We encourage all genders to apply, with priority given to women across all global markets and historically underrepresented populations.

I invite you to apply here today, it’s valued at $4500 and it is 100 per cent free.

The change I’ve witnessed from women taking advantage of opportunities like this is drastic.

Two journeys particularly stand out to me, those of Shammah Saratu Yaro and Caleb Yeboah have been inspiring and transformative.

The scholarships have helped them attain certifications, and access free vouchers enabling them to take exams and land new DevSecOps roles, accelerating their career growth and leadership opportunities. 

You can begin your journey today.

Setting aside a few weeks to continue or begin your personal and professional development with applicable skills in the tech industry is a lifelong practice that will keep you ahead of the curve, for AI and beyond.

Chaitra Vedullapalli Bio:

Chaitra Vedullapalli is the award-winning Co-Founder and CMO of Meylah and Co-Founder and President of Women In Cloud.

In her 26 years in tech, Chaitra has driven billion-dollar expansions for both Microsoft and Oracle, has been recognised with the Forbes 1000 Next Entrepreneur title, Microsoft Women’s Leadership Award, set a new Guinness World Record, and is listed as one of 100 Most Innovative MarTech Leaders by World Marketing Congress.

Presenting before the UN, at TedX, Grace Hopper Celebration, and Microsoft Inspire, she is a purpose-driven, strategic, high-growth thought leader who seamlessly bridges business and technology to help companies globally scale and drive digital economic development. 

Her mission is to generate $1B in new net economic access for women entrepreneurs and professionals by 2030 through global partnerships with corporations, community leaders, and policymakers.

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Taking charge of your well-being: A guide to pelvic health

By Gloria Kolb, Co-founder & CEO – Elitone

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Pelvic health is a vital yet often overlooked aspect of overall well-being. It encompasses the proper functioning of the muscles, ligaments, and tissues that support the pelvic organs and plays a critical role in daily activities and quality of life. 

Despite its importance, pelvic health remains shrouded in silence and stigma.

Many people hesitate to discuss issues like incontinence, pelvic pain, sexual health concerns, and pelvic organ prolapse due to societal taboos and misconceptions.

This reluctance to talk openly can lead to prolonged suffering and a diminished sense of well-being.

By shedding light on the various aspects of pelvic health, we aim to break the taboo, educate on everyday issues, and empower individuals to take proactive steps in managing their pelvic health.

Understanding the significance of pelvic health and addressing problems early can lead to a more vibrant, healthy, and fulfilling life.

Understanding pelvic health

Pelvic health refers to the optimal functioning of the pelvic floor, which forms a supportive base for the pelvic organs, including the bladder, uterus, and rectum.

These muscles play a crucial role in urinary and faecal continence, sexual function, and support during physical activities.

The pelvic floor acts like a hammock, providing stability and support to the pelvic organs.

When these muscles are strong and functioning correctly, they help maintain proper organ positioning and function.

However, various factors such as aging, childbirth, surgery, obesity, and chronic straining can weaken or damage the pelvic floor muscles, leading to a range of health issues.

The importance of pelvic health

Neglecting pelvic health can lead to various complications, from mild discomfort to severe disruptions in daily activities.

For instance, incontinence can result in social embarrassment and a reluctance to engage in physical activities, while chronic pelvic pain can interfere with work, exercise, and personal relationships.

Sexual health issues related to pelvic floor dysfunction can affect intimacy and emotional connection with partners.

The long-term consequences of ignoring pelvic health can be profound, leading to chronic pain, mental health struggles, and decreased independence.

Early intervention and proactive management of pelvic health are essential for preventing these outcomes and promoting overall well-being.

Recognising the importance of pelvic health empowers individuals to seek appropriate care and take steps to maintain or restore their pelvic floor function, ultimately enhancing their quality of life.

Common pelvic health issues

Understanding the common issues that affect pelvic health is crucial for recognising symptoms early and seeking appropriate care. Some of the most prevalent pelvic health problems include:

  • Incontinence: This refers to the involuntary leakage of urine or faeces. Different types include stress, urge, overflow, and functional incontinence. Causes range from weakened pelvic floor muscles to nerve damage and underlying health conditions.
  • Pelvic pain: This discomfort in the lower abdomen and pelvic region can be brought on by chronic conditions like endometriosis and interstitial cystitis. Acute issues such as infections or injuries can cause persistent pain, impacting daily activities and emotional well-being.
  • Sexual health concerns: These include dyspareunia (painful intercourse), decreased libido, and erectile dysfunction. Causes can be hormonal, muscular, or psychological. Addressing these concerns is vital for maintaining intimacy and relationship satisfaction.
  • Pelvic organ prolapse: This occurs when the pelvic organs descend and fall out of place, with common causes including childbirth, aging, and obesity. Symptoms range from heaviness in the pelvic area and discomfort sitting down to urinary and bowel dysfunction. Early intervention is essential for managing symptoms.

Understanding and addressing these common pelvic health issues is vital for improving quality of life and overall well-being.

Awareness, open communication, and timely medical intervention can help manage these conditions effectively, empowering individuals to lead healthier, more fulfilling lives.

Diagnosis and treatment options

Pelvic health issues are typically diagnosed through routine pelvic examinations, which assess the position and support of pelvic organs and can identify problems such as prolapse and muscle weakness.

Imaging tests, including ultrasound, MRI, and CT scans, provide detailed images of the pelvic area, helping to diagnose structural problems and guide treatment plans.

Additionally, questionnaires and symptom checklists assist healthcare providers in understanding the severity and impact of symptoms on daily life, aiding in accurate diagnosis.

Treatment options for pelvic health issues fall into two main categories: conservative measures and medical interventions.

Conservative measures often serve as the first line of defence.

Lifestyle modifications, such as diet changes, bladder training, weight management, and avoiding heavy lifting, can alleviate symptoms.

Pelvic floor physical therapy, involving exercises designed to strengthen the pelvic floor muscles, can improve function and reduce symptoms.

Non-surgical devices, like pessaries and stimulation, can help manage prolapse and incontinence without the need for surgery. 

When conservative measures are insufficient, medical interventions may be necessary to help manage pain, inflammation, and symptoms of incontinence or prolapse.

Minimally invasive procedures such as injections or medication may offer relief for various pelvic health issues.

In severe cases, surgical options like pelvic floor reconstruction and sling procedures for incontinence or prolapse may be required.

It is crucial to carefully weigh the risks and benefits of surgery with a healthcare provider. 

Treatment should be tailored to each person’s specific condition, symptoms, lifestyle, and preferences.

However, it is key to note that more medical interventions may not be more productive than conservative ones.

Holistic approaches to pelvic health

Adopting holistic approaches to pelvic health can significantly enhance overall well-being by addressing physical, mental, and emotional aspects.

Regular exercise, particularly pelvic floor exercises like Kegels, strengthens these muscles, while whole-body activities such as yoga and Pilates improve core strength and flexibility to support pelvic health.

Specific yoga poses like Bridge Pose and Goddess Pose target the pelvic floor, while mindfulness practices reduce stress.

Nutrition is also vital. A fibre-rich diet prevents constipation, which reduces pelvic strain, while hydration helps maintain urinary health, and anti-inflammatory foods help manage pelvic pain.

Protein can help build the needed pelvic muscles.

Alternative adjunct therapies, including acupuncture, chiropractic care, and biofeedback, can complement traditional treatments in alleviating pain, improving muscle function, and enhancing overall pelvic health.

Integrating these holistic methods fosters a balanced approach to maintaining and improving pelvic health, leading to a healthier, more fulfilling life.

Breaking the taboo and empowering yourself

Breaking the taboo surrounding pelvic health is essential for empowering individuals to take charge of their well-being.

Societal stigma often discourages open discussions about pelvic health issues, leaving many people feeling isolated and ashamed of their experiences.

By normalizing conversations about pelvic health, individuals can overcome this stigma and access the support and resources they need.

Empowering oneself to take charge of pelvic health begins with education and awareness.

Understanding the signs and symptoms of pelvic health issues allows individuals to recognise when they need help and seek appropriate care.

Open communication with healthcare providers is crucial for discussing concerns and developing personalised treatment plans.

Additionally, joining support groups or seeking guidance from mental health professionals can provide valuable emotional support and validation.

By embracing a proactive approach to pelvic health and advocating for their own well-being, individuals can reclaim control over their bodies and lives.

By fostering a culture of openness and support, we can break down barriers and ensure everyone feels empowered to prioritise their pelvic health and live their lives to the fullest.

Gloria Kolb is the CEO and co-founder of Elitone, an FDA-cleared, non-invasive wearable treatment for women with urinary incontinence. Elitone has won “Best New Product” by My Face My Body awards, Sling Shot 2020, and numerous startup pitch awards.

As an inventor with 30  patents, Gloria’s accolades include being featured in Forbes as a Top Scientist Driving Innovation in Women’s Health.

Her creative designs and problem-solving abilities have earned her recognition, such as Boston’s “40 Under 40” Award and MIT Review’s “World’s Top Innovators under 35”.

With Mechanical Engineering degrees from MIT and Stanford and an Entrepreneurship MBA from Babson College, Gloria’s expertise extends to consulting, where she evaluates technology and clinical markets for various inventions and startups.

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