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Smart lactation pads can monitor safety of breast milk in real time

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Scientists have developed a lactation pad equipped with sensing technology that allows parents of newborns to monitor breast milk in real time. The work shows that the device is capable of ensuring that breast milk contains safe levels of the painkiller acetaminophen, which is often prescribed after childbirth and can be transferred to breastfeeding infants.

To make the device, the researchers installed electrodes and tiny channels into a lactation pad – an apparatus that nursing parents often wear throughout the day to protect their clothes from leaking breast milk.

The smart lactation pad functions by measuring samples of the milk for acetaminophen as lactating parents go about their regular routines without requiring additional effort from the parent.

“Our device represents a major innovation,” said first author Maral Mousavi, an assistant professor of biomedical engineering at the University of Southern California (USC).

“It is the first wearable tool for direct biochemical analysis in breast milk and the first lactation pad embedded with real-time sensing technology. This technology has the potential to empower lactating individuals with actionable health insights, supporting both maternal and infant health in ways that have never before been possible.”

 

 

Since the smart pad continuously monitors levels of acetaminophen in the milk throughout the day, it also offers a tool for scientists to better understand how drugs are transferred into breast milk, says Mousavi.

“While it is generally safe at recommended doses, acetaminophen overexposure is a leading cause of acute liver failure in children,” she said.

“It remains the most common reason for liver transplants related to drug toxicity.”

The researchers were inspired to build the lactation pad after a graduate student in their research group gave birth and was prescribed acetaminophen to manage her postpartum pain.

Despite the importance of breast milk as a source of nutrition for infants and its ability to help their fragile immune systems develop, the team found that few technologies existed to monitor its safety in real time. While a few companies offer mail-in services, these services involve collecting samples in specialised kits that can be costly and waiting days or weeks for results.

“Given the risks and the critical decision-making parents face around breastfeeding and medication use, we wanted to create a tool that empowers them with real-time, personalised information rather than leaving them to rely on generalized drug-safety charts or delayed lab testing,” said Mousavi.

The team hopes that the smart lactation pad can help parents make more informed decisions about breastfeeding after taking medications, such as optimising the “pump and dump” strategy or discarding breast milk when drug levels are the highest.

In addition to painkillers, the authors note that new mothers are also commonly prescribed antibiotics or anti-fungals, and although these medications are generally considered safe to take while breastfeeding, they aren’t always benign.

While the version of the smart pad described in this study was developed to measure acetaminophen, Mousavi says that it can be adapted to detect other drugs and biomarkers for assessing health.

For example, Mousavi and colleagues recently demonstrated another lactation pad with an embedded sensor designed to monitor glucose levels in breast milk—a function which she says could help parents manage their nutrition and address conditions such as gestational diabetes.

Currently, the device is only able to measure milk produced from natural leakage, meaning its applications may be limited when little leakage occurs. The pads are also disposable, so a new lactation pad is required for each new test. The researchers are currently working to develop a version of the device that analyses pumped milk to offer a more accessible and convenient testing option for parents.

Pregnancy

Stroke prevention and treatment during and after pregnancy key to women’s health – AHA

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Stroke prevention requires aggressive blood pressure control and rapid recognition of symptoms in pregnancy and postpartum, a new scientific statement urges.

The guidance details risk factors for pregnancy-related stroke and offers suggestions for prevention, rapid diagnosis, timely treatment and recovery during pregnancy and postpartum.

A stroke occurs in approximately 20 to 40 of every 100,000 pregnancies and is estimated to account for around four to six per cent of pregnancy-related deaths annually in the US.

The statement was published by the American Heart Association and endorsed by the American College of Obstetricians and Gynecologists.

Eliza Miller is chair of the writing group and associate professor of neurology at the University of Pittsburgh.

She said: “When a stroke occurs during pregnancy or the postpartum period, it can lead to serious complications for both the mother and baby, including neurological deficits, long-term disability, increased risk of future strokes and death.

“Controlling blood pressure and other stroke risks before and after delivery, responding immediately to stroke warning signs and providing timely treatment can help save lives and improve outcomes for mothers and their babies.”

There are two types of stroke: an ischaemic stroke occurs when a blood vessel supplying blood to the brain is blocked by a clot, while a haemorrhagic stroke occurs when a blood vessel ruptures and bleeds into the brain.

Risk factors for pregnancy-associated stroke include chronic hypertension (high blood pressure before pregnancy or diagnosed before 20 weeks), preeclampsia (a dangerous condition causing high blood pressure in pregnancy), advanced maternal age (35 years or older), diabetes, obesity, migraine with aura, infections, heart disease and clotting disorders.

Stroke disproportionately affects people of racial and ethnic minorities. A 2020 meta-analysis found that pregnant Black women are twice as likely to have a stroke compared with pregnant white women, even after adjusting for socioeconomic factors.

The statement authors emphasise that the majority of maternal strokes are preventable with earlier and more aggressive blood pressure control.

“Preeclampsia and eclampsia can occur before, during or after delivery, and the early postpartum period is actually the highest risk time for stroke.

“Very close monitoring of blood pressure is essential,” said Miller.

The statement urges all healthcare professionals who care for pregnant patients, including obstetricians, family medicine practitioners and nurses, to be trained to recognise stroke symptoms so they can promptly start treatment.

“It is crucial for women who are pregnant or have recently given birth and have symptoms of new neurological deficits or severe headache, especially if they also have elevated blood pressure, to be immediately evaluated for possible stroke,” said Miller.

The authors emphasise that pregnancy is not a reason to delay or interfere with recommended treatment for acute stroke.

Various anti-clotting medications are available that are safe for pregnant and lactating women, and mechanical thrombectomy (surgical removal of a blood clot) may be needed for patients with large-vessel blockages.

Survivors of pregnancy-associated stroke face unique challenges such as caring for an infant and require support from a multidisciplinary rehabilitation team.

Mood and sleep disorders are common after stroke and may be intensified by postpartum factors such as hormonal shifts, breastfeeding and disrupted sleep.

Miller said: “Babies depend on their mothers’ well-being, and supporting recovery after stroke, both emotionally and practically, is essential so mothers can heal and families can thrive.”

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Insight

70% of UK mothers feel overloaded, study finds

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Seven in 10 UK mothers feel overloaded and almost half have a mental health issue such as anxiety or depression, new research finds.

A survey of mothers’ experiences in 12 European countries also found most of those in Britain still do the majority of household tasks and caregiving alone, and that the UK was among the worst for motherhood disadvantaging a woman’s career.

The research was conducted by pan-European campaign group Make Mothers Matter, which surveyed 800 mothers in each of the 12 countries about the psychological impact of giving birth and the pressures of motherhood.

It found that 71 per cent of UK mothers feel overloaded, compared with 67 per cent across Europe, while 47 per cent report mental health issues including burnout, compared with 50 per cent in Europe as a whole.

Some 31 per cent of UK respondents felt motherhood had a negative effect on their career, higher than the 27 per cent average, with Ireland the highest at 36 per cent.

However, some measures showed UK mothers find it easier to balance work and caring. Only 11 per cent said their partner did not take paternity leave, far lower than the 25 per cent average across the 12 countries.

The findings prompted calls for GPs and NHS maternity and health visiting services to routinely ask mothers about their mental wellbeing and provide more help to those who need it.

Prof Alain Gregoire, a perinatal psychiatrist and honorary president of the Maternal Mental Alliance UK, said that despite improvements in NHS care in recent years, too many mothers were left “suffering in silence.”

“Much of the suffering maternal mental ill-health causes goes undetected, despite mothers’ repeated contact with maternity staff, health visitors and GPs.

“There’s a stigma associated with seeking mental health help and support, there’s not enough of that around, so women face enormous barriers to getting help, and health professionals don’t get enough training in spotting maternal mental health problems.”

He said easy access to talking therapies, which offer psychological support, would “provide an unstigmatised way of accessing help and relieve huge amounts of the suffering for mothers and families.”

Angela McConville, chief executive of the NCT parenting charity, said: “Pregnancy, birth and early parenthood are periods of heightened vulnerability, but significant gaps remain in the care and services offered to women and new parents, particularly after birth.

“After birth, women need services that provide localised mental health support, unbiased and evidence-based information, and regular, reliable touchpoints, from health visitors through to postnatal GP check-ups.”

“Instead, many women encounter a fragmented postnatal care system that is dangerously underfunded and understaffed, leaving them feeling isolated at a time when support is most critical.”

Make Mothers Matter said mothers across Europe are experiencing higher levels of stress, cognitive overload and emotional exhaustion today than when it undertook a similar survey in 2011.

A Department of Health and Social Care spokesperson said: “Every mother deserves to feel supported when it comes to their mental health, and we are determined to ensure help is there when it’s needed.

“A wide range of support is available on the NHS for new and expectant mothers, including access to specialist perinatal services, talking therapies and help from health visitors.

“We are investing more in mental health services with an extra £688m this year, we’ve hired an extra 7,000 mental health workers, and we’re providing more NHS talking therapies.”

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Wellness

Women being failed by underfunded UK postnatal care, report warns

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Women in the UK are being failed by a “dangerously underfunded and understaffed” postnatal care system, a new report has warned.

Thousands of new mothers feel unsafe, unsupported and overwhelmed in the weeks and months after birth, according to the National Childbirth Trust (NCT).

The report included a survey of 2,000 new and expectant parents across the UK, including 500 women who were pregnant at the time.

Angela McConville, chief executive of the NCT, said: “Every major report has shown that the UK’s maternity system is failing to provide safe, compassionate care.”

“Becoming a parent is rarely one-dimensional. It can be joyful, frightening, overwhelming and messy, often all at once, and that kaleidoscope of emotions is shaped profoundly by the care and support families receive.

“At one of the most vulnerable times in their lives, too many parents tell us they feel unsafe, unsupported and denied genuine choice.”

Almost a quarter, 24 per cent, said they did not have regular access to NHS staff in the weeks and months after birth.

Nearly nine in 10, 87 per cent, reported feeling overwhelmed at least some of the time, with 22 per cent always feeling overwhelmed. Meanwhile, 62 per cent reported feeling lonely sometimes, with 12 per cent saying they felt lonely all of the time.

More than half, 59 per cent, of pregnant women said they worried about their mental health.

Michelle Welsh, Labour MP for Sherwood Forest and chair of the all-party parliamentary group on maternity, said the NCT report was “deeply troubling”.

It confirmed what families and NHS staff had been telling the group for years, she added.

“Too many parents are being left without a safety net at one of the most important and vulnerable times of their lives,” she said.

“Feeling overwhelmed, isolated or unsafe should never be considered a normal part of pregnancy, birth or early parenthood.”

Last year, Wes Streeting, the health secretary, ordered a review into maternity and neonatal care (care for newborns) in England.

Led by Lady Valerie Amos, it is due to report this spring and covers 12 NHS trusts. Some families have called for a full statutory inquiry.

McConville said investment, staffing, training and accountability “must be prioritised to ensure every parent can feel confident, supported and heard”.

Responding to the report, the government said women should get the support they need in their baby’s first months of life and “stark inequalities” were “unacceptable”.

A Department of Health and Social Care spokesperson added: “We expect all women to be offered a postnatal check-up with their GP at six to eight weeks after birth, which includes physical and mental health support.

“This government is taking urgent action to improve maternity services – launching a national maternity and neonatal investigation, which includes identifying the drivers of inequalities, investing over £130m to make maternity and neonatal units safer, rolling out a programme to reduce avoidable brain injuries, and backing Martha’s Rule.”

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