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6 female entrepreneurs changing the business landscape today

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What was once a highly male-dominated business world is now seeing a significant transformation with the rise of ambitious female entrepreneurs.

The number of women-owned businesses in the US has grown almost twice the rate of male-owned ones between 2019 and 2023. They now account for close to 40% of all enterprises, generating $2.7 trillion in revenue and 12.2 million jobs.

And there are some inspiring female entrepreneurs leading them. These are women who have broken the glass ceiling to achieve outstanding success with sheer passion and determination.

Here are six of our favourites.

1. Oprah Winfrey

Known as one of the most influential females in the world, Oprah Winfrey came to fame as the host of The Oprah Winfrey Show, which ran for 25 years with phenomenal success.

But she is not just a TV show host. At the age of 32 years, Winfrey started her own production company, Harpo Productions, which went on to produce hits, such as The Dr. Oz Show, as well as her namesake talk show.

This set the stage for a multimillion-dollar media empire, leading to Oprah Winfrey Network (OWN), O, The Oprah Magazine, and various other enterprises.

Winfrey has also invested in multiple ventures, notably real estate and businesses, including Weight Watchers, which she exited this year.

She is now one of the wealthiest self-made women in the US and shares her success with the less privileged with Oprah’s Angel Network.

2. Rihanna

Rihanna’s net worth is around $1.4 billion, and it is not only due to her vocal talents. Her entrepreneurial skills have led to the rapid growth of her wealth, despite not releasing a music album since 2016.

Robyn Rihanna Fenty, better known to the world as Rihanna, has her own label, Westbury Road Entertainment, which she founded in 2005. She also co-owns Tidal, a music streaming service.

But a large part of her earnings come from her business ventures in fashion and beauty. Rihanna launched Fenty Beauty in 2017 in a bid to introduce a range of cosmetic products for diverse skin types. That year, it made Time magazine’s The 25 Best Inventions of 2017 list.

Today, the Fenty empire includes the lingerie brand Savage X Fenty, the Fenty fashion collection, and Fenty Skin, which produces skincare products. This year, she also introduced Fenty Hair, a haircare brand for different hair types.

3. Arianna Huffington

Unlike others on this list, Arianna Stassinopoulos Huffington began her entrepreneurial career much later in her life, at the age of 54.

She co-founded The Huffington Post in 2005, carving out a niche in the digital media space, focused on news in politics, business, and entertainment.

The platform’s rapid rise to fame became evident when AOL purchased it for $315 million in 2011. Over the years, The Huffington Post has also gone international, launching in Canada, the UK, Spain, France, Italy, Germany, and Japan.

Later on, Huffington also launched Thrive Global with the aim of helping readers combat stress and burnout and create a more balanced life. One year later, in 2017, this company was valued at $120 million.

Huffington’s legacy carries on through her business ventures in digital media and journalism. She has become an influential figure in the US, playing an instrumental role in reshaping how we see work and well-being.

4. Whitney Wolfe Herd

Born in 1989, Whitney Wolfe Herd has appeared in Time’s 100 Most Influential People list and Forbes’ 30 Under 30 for the remarkable success she achieved with the dating app Bumble.

When she was 22 years old, Wolfe Herd co-founded Tinder, together with Sean Rad and Justin Mateen. Two years later, she launched Bumble as a female-centric dating app.

This quickly grew in popularity, attracting millions of users and placing the app only second to Tinder.

And in 2021, when Wolfe Herd was only 31, Bumble went public and reached a valuation of $7 billion. This made her the youngest female to take a company public in America and the youngest female billionaire in the world.

Her achievements in business have had a profound impact on women, too, especially in empowering and inspiring female entrepreneurs, both young and old.

5. Payal Kadakia

The tech space seems to attract more and more women entrepreneurs striving to challenge the traditional male dominance in the field.

Payal Kadakia is a good example of this.

At the age of 29, Kadakia founded ClassPass, the popular subscription-based fitness and wellness app that serves as a search engine and booking platform for gyms, studios, spas, salons, and other related places.

The app was first launched in 2012 under the name Classtivity, which was rebranded as ClassPass in 2014.

It quickly drew attention, gaining 45 million bookings by the end of 2017 and a $1 billion valuation by 2020. Now, ClassPass is available across 30 countries and works with tens of thousands of businesses globally.

Kadakia’s entrepreneurial skills and vision have been recognized throughout the years, winning her a spot in Fortune’s 40 under 40 and Fast Company’s 100 Most Creative People list.

6. Tory Burch

As with most other enterprises, Tory Burch’s multibillion-dollar fashion empire has had humble beginnings. She has expanded what started as a simple store in Manhattan in 2004 to over 370 stores across several countries in less than two decades.

In 2023, the company’s revenue reached nearly $2 billion.

With this level of achievement, Burch didn’t just make the pages of top fashion magazines like Harper’s Bazaar and Glamour. She has been recognized for leadership and entrepreneurial acumen in the business world, too.

Burch has been on Time magazine’s 100 Most Influential People in the World list as well as Forbes’ The World’s 100 Most Powerful Women list.

She has also won recognition for work carried out through the Tory Burch Foundation, founded to support female entrepreneurs with education, mentoring, small business loans, and networking opportunities.

To Conclude

From Oprah Winfrey, Rihanna, and Arianna Huffington to Whitney Wolfe Herd, Payal Kadakia, and Tory Burch, female trailblazers have taken over the business landscape (once considered a man’s world), generating trillions of dollars in revenue each year.

Their sense of purpose, passion, and determination will, no doubt, serve to inspire millions of women across America and beyond to pursue their life goals and reach their full potential.

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Insight

Topical HRT protects bone density in women with period loss – study

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Transdermal HRT best protects bone density in women with functional hypothalamic amenorrhoea, a condition that stops periods, a review of trials has found.

The meta-analysis pooled randomised clinical trials involving 692 participants and found transdermal hormone replacement therapy and teriparatide increased bone mineral density by between 2 and 13 per cent.

Functional hypothalamic amenorrhoea can follow anorexia or intense exercise. Bone mineral density measures bone strength and the amount of mineral in bone.

Around half of women with the condition have low bone mineral density, compared with about 1 per cent of healthy women, and their fracture risk is up to seven times higher.

The research was conducted by scientists at Imperial College London and Imperial College Healthcare NHS Trust.

Professor Alexander Comninos, senior author of the study and consultant endocrinologist at the trust, said: “Bone density is lost very rapidly in FHA and so addressing bone health early is very important to reduce the lifelong risk of fractures.

“Our study provides much needed comparisons of all the available treatments from all available studies.

“Clearly the best treatment is to restore normal menstrual cycles and therefore oestrogen levels through various psychological, nutritional or exercise interventions – but that is not always possible.

“The foundation for bone health is good calcium and vitamin D intake (through diet and/or supplements) but we have additional treatments that are more effective.”

When FHA is diagnosed, clinicians first try to restore periods through lifestyle measures, including psychological and dietary support, but these can fail. Guidelines then recommend giving oestrogen, though the best form was unclear.

The team reviewed all prior randomised trials comparing therapies, including oral and transdermal oestrogen, and also assessed teriparatide, a prescription bone-building drug used for severe osteoporosis.

They found no significant benefit for oral contraceptive pills or oral hormone therapy.

A recent UK audit reported that about a quarter of women with anorexia-related FHA are prescribed the oral contraceptive pill for bone loss; the study suggests using transdermal therapy instead.

Comninos said: “Our goal is simple: to help women receive the right treatment sooner and to protect their bone health in the long-term.

“We hope this study provides clinicians with better evidence to choose transdermal oestrogen when prescribing oestrogen and so inform future practice guidelines.

“Right now, millions of women with FHA may not be receiving the best treatments for their bone health.”

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Insight

AI cuts interval breast cancers in Swedish trial

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An AI tool cut interval breast cancers by 12 per cent in a Swedish screening trial of more than 105,000 women.

The study also found 27 per cent fewer aggressive breast cancers detected at screening when AI was used.

Interval cancers are cancers found between routine screening appointments because they were missed at the original scan. They are often more dangerous and linked to higher death rates than cancers found at screening.

The MASAI trial is described as the first large randomised study to test whether AI can improve mammography screening, which uses low-dose X-rays to examine breast tissue for signs of cancer.

The AI tool, called Transpara Detection and developed by ScreenPoint Medical, supported radiologists in analysing mammography images.

Earlier results from the same trial showed that Transpara Detection increased cancers found by 29 per cent and reduced radiologist workload by 44 per cent compared with standard double-reading, where two radiologists independently review each scan.

The latest findings indicate higher accuracy with AI support. Sensitivity, the ability to detect cancer, was 6.7 percentage points higher in the AI group while specificity, the ability to rule out healthy cases, was maintained. Results were similar across age groups and breast density levels.

Women screened with AI had 16 per cent fewer invasive interval cancers and 21 per cent fewer large interval cancers than those in the standard screening group.

The system also helps doctors assess risk more precisely by subdividing suspicious findings into BI-RADS 4 categories A, B and C. BI-RADS (Breast Imaging Reporting and Data System) is a standardised scale that guides whether a patient needs closer monitoring, further tests or treatment.

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Mental health

Fear of ageing may age women faster, study suggests

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Ageing anxiety may accelerate biological ageing in women, with fears about worsening health linked to faster epigenetic ageing, according to new research.

The study found that greater anxiety about growing old was associated with accelerated epigenetic ageing, as measured by the DunedinPACE clock, based on biological markers in blood samples.

Epigenetic changes are shifts in how genes are switched on or off without altering DNA itself, which can influence how the body ages and functions.

“Our research suggests that subjective experiences may be driving objective measures of ageing,” said Mariana Rodrigues, a PhD student and the first author of the study.

“Ageing-related anxiety is not merely a psychological concern, but may leave a mark on the body with real health consequences.”

Researchers analysed data from 726 women in the Midlife in the US study.

Participants were asked how much they worried about becoming less attractive with age, having more health issues and being too old to have children.

Blood samples were used to assess ageing with two epigenetic clocks: DunedinPACE, which estimates the pace of biological ageing, and GrimAge2, which estimates cumulative biological damage.

The study was conducted by researchers at NYU School of Global Public Health.

Worrying about declining health showed the strongest links with epigenetic ageing, while anxiety about attractiveness and fertility was not significantly associated with biological markers.

The authors suggest health worries are more common and persist over time, whereas concerns about appearance and reproduction may fade with age.

“Women in midlife may also be multiple in roles, including caring for their ageing parents,” Rodrigues said.

“As they see older family members grow older and become sick, they may worry about whether the same thing will happen to them.”

The authors caution that the study offers a snapshot in time and other factors may influence these biological changes.

When analyses were adjusted for health behaviours such as smoking and alcohol use, the link between ageing anxiety and epigenetic ageing decreased and was no longer significant.

“Our research identifies ageing anxiety as a measurable and modifiable psychological determinant that seems to be shaping ageing biology,” said Adolfo Cuevas, associate professor of social and behavioural sciences and the study’s senior author.

They call for more research to clarify how this anxiety influences ageing over time, to guide support for those experiencing ageing anxiety.

“Ageing is a universal experience.” Rodrigues said.

“We need to start a discourse about how we as a society, through our norms, structural factors and interpersonal relationships, address the challenges of ageing.”

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