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Menopause

Work stress top trigger of perimenopause symptoms, says Health & Her report

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The menopause support platform Health & Her has found that 80 per cent of women reported at least one trigger of perimenopause symptoms, including stress, caffeine, alcohol, and sugar.

The research conducted on 55,047 women going through perimenopause has shown that 54 per cent of participants reported stress at work as a major trigger. Examples of work stressors might be meeting a tight deadline, presenting in front of clients, attending performance reviews and taking part in social events.

“There are an estimated three million women currently going through perimenopause in the UK,” says Dr Rebeccah Tomlinson, GP menopause specialist at Health & Her.

“Although symptoms are primarily due to falling sex hormone levels, many of these women are unaware of the way mental health, lifestyle and diet choices can trigger the frequency and severity of their perimenopause symptoms.

“The reason stress at work is cited so frequently by women is because oestrogen helps maintain cortisol levels, so when oestrogen levels start to drop things go out of balance. It then becomes a vicious circle. The more you stress, the more you experience mind, mood, and sleep problems.”

Health & Her research found stress of this nature highly correlated to mind and mood symptoms of perimenopause including anxiety, low mood, poor concentration, brain fog and memory loss.

With more than four million perimenopausal or menopausal women currently in the workplace and one in ten leaving the workplace, finding ways to help them manage stress to minimise triggering symptoms is vital.

The research confirms a link between stressful events and worse menopause symptoms. However, according to the report, it is not necessarily the event that exacerbates symptoms but how a woman responds to that event.

Just under half (47 per cent) of the women surveyed reported this as trigger alongside anxiety, poor concentration, memory loss and heart palpitations.

Two in five women reported they started to experience more sensitivity to caffeine as they progressed through perimenopause.

Dr Rebeccah says this happens due to the caffeine found in tea, coffee and energy drinks that accelerates the nervous system, increases alertness, and interferes with the absorption of vitamins and minerals.

“Whilst it might seem like a good pick me up after a bad night’s sleep, caffeine can have a detrimental effect on sleep, causing insomnia which is one of the most common symptoms of perimenopause,” she adds.

Additionally, four in ten women found that they experienced an issue with alcohol tolerance.

Alcohol causes the blood vessels to dilate and raise the internal body temperature, leading to more hot flushes and night sweats, higher levels of cortisol, disrupted sleep, mood swings and increased dehydration.

Sugar posed a moderate issue for one third of the women. Sugary snacks are known to cause rapid high spikes in blood sugar levels.

High blood sugar, insulin resistance and metabolic syndrome are linked to hot flushes in perimenopausal women while dips in blood sugar can impact energy and mood levels. These spikes and dips can lead to a cycle of snacking on quick fix foods that can exacerbate menopausal weight gain and other symptoms such as bloating, digestive issues and memory loss, the researchers say.

Kate Bache, co-founder at Health & Her, says: “Seeing stress featuring twice in the top five triggers, it’s no wonder 15 per cent of women experiencing perimenopausal women have called in sick due to their symptoms.

“Women are struggling to perform at their job, due to the severity of their symptoms and lack of support.

“Almost a quarter of perimenopausal women surveyed admitted to making mistakes at work, while six per cent had to skip meetings to deal with their symptoms.”

Bache’s Health & Her aims to support perimenopausal and menopausal women through its Employer Menopause Support Plan.

The package offers clinic access to menopause-specialist GPs, advice, managerial and employee training, digital tools and webinars to help women track and manage menopause symptoms and support the employees who work with them.

“Businesses need to learn to adapt, create a space and culture that supports perimenopausal women to retain them in the workplace,” says Bache.

“These women are at a point in their lives where they have the experience, talent, and skills to positively contribute to the workforce. By offering the right help and developing the right plan around they will be able to continue to progress in their careers, rather leaving due to their symptoms.”

Menopause

Abdominal obesity may lead to more severe menopause symptoms – study

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Abdominal obesity may lead to worse menopause symptoms, including forgetfulness, irritability and night sweats, a new study suggests.

The findings point to a possible link between fat stored around the waist and more severe midlife symptoms.

Researchers said waist-to-height ratio could help identify women who may benefit from more targeted support.

Dr Monica Christmas is associate medical director for The Menopause Society.

Christmas said: “Unintended weight gain during the menopause transition, especially in the midsection, is one of the most commonly reported complaints, with the most significant gains experienced in the years leading up to the final menstrual period and a couple of years after.

“This not only affects self-image but also imposes negative health risks and, as the study highlights, is associated with higher prevalence and severity of menopause symptoms.”

The study used data from more than 1,100 women who took part in the Study of Women’s Health Across the Nation.

Abdominal obesity is a build-up of fat around the waist. It often includes visceral fat, which is deep, active fat surrounding internal organs.

This type of fat releases inflammatory proteins and toxic fatty acids that can contribute to insulin resistance, cardiovascular disease, high blood pressure and a higher risk of some cancers.

Insulin resistance means the body does not respond properly to insulin, the hormone that helps control blood sugar.

The Menopause Society said abdominal obesity is estimated to affect more than 60 per cent of menopausal women.

As oestrogen levels fall during menopause, women tend to store more fat around the waist rather than the hips, even if their overall weight does not change.

The researchers noted that obesity patterns and menopause symptom burden can vary by region, but research into the effect of abdominal obesity on these symptoms remains limited.

They also said earlier studies have mainly looked at single symptoms, rather than how symptoms connect with each other.

In this study, researchers used network analysis, a method that looks at how symptoms are linked, to compare symptom patterns in women with and without abdominal obesity.

They identified abdominal obesity using waist-to-height ratios, which compare waist size with height and can be used as a simple measure of health risk linked to body fat around the middle.

The researchers concluded that women with abdominal obesity had both a higher prevalence and greater severity of a range of symptoms, as well as a distinct symptom network structure.

In particular, women with abdominal obesity reported a higher prevalence and greater severity of dizziness, hot flashes and night sweats than women without abdominal obesity.

Sleep disturbances and palpitations were also reported more often in women with abdominal obesity. Palpitations are feelings of a fast, fluttering or pounding heartbeat.

The researchers said assessment of abdominal obesity using waist-to-height ratios may help stratify women who are likely to benefit from targeted, network-based interventions rather than isolated symptom management.

Christmas said: “Educating women early about healthy lifestyle interventions to prevent midlife weight gain is key to improving mental and physical well-being during a tumultuous time frame.”

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Perimenopause may offer “window of opportunity” for heart disease prevention

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Perimenopause may offer a key window to spot heart disease risk earlier, with women in the transition twice as likely to have low heart health scores, new research suggests.

The findings suggest the transition to menopause could be an important time to reassess risk and prompt lifestyle changes.

Garima Arora is senior author of the study and professor of medicine in the division of cardiovascular disease at the University of Alabama at Birmingham.

Arora said: “Mid-life women should think of the perimenopausal period as a ‘window of opportunity.’

They should be proactive and not wait until they reach menopause to start checking their blood pressure, cholesterol and blood sugar levels.

“Women should talk with their health care team about their reproductive status and any changes they are experiencing. It may be the perfect time to get a baseline for their heart health.”

The analysis included 9,248 women aged 18 to 80 who took part in the National Health and Nutrition Examination Survey between 2007 and 2020.

Researchers used Life’s Essential 8, a heart health score developed by the American Heart Association. It measures diet, physical activity, tobacco use, sleep, blood pressure, cholesterol, body weight and blood sugar on a 100-point scale.

Median scores fell as women moved through reproductive stages, from 73.3 out of 100 in premenopausal women to 69.1 in perimenopausal women and 63.9 in postmenopausal women.

Among the individual Life’s Essential 8 measures, diet consistently had the lowest scores and continued to decline across all reproductive stages.

After accounting for age, perimenopausal women were twice as likely to have a low overall score as premenopausal women.

They were also 76 per cent more likely to have a low cholesterol score and 83 per cent more likely to have a low blood sugar score.

The researchers said fluctuations in oestrogen levels during perimenopause may contribute to lower cardiovascular health because they may affect cholesterol, insulin resistance, blood pressure and weight management.

Insulin resistance means the body does not respond properly to insulin, the hormone that helps control blood sugar.

Sleep duration scores remained high across all reproductive stages, despite perimenopausal women reporting difficulty sleeping, suggesting sleep quality may be more affected than sleep length.

Amrita Nayak, lead author of the study and research fellow in the division of cardiovascular disease at the University of Alabama at Birmingham, said the findings highlight a point where risk may begin to rise.

She said: “Our analysis highlights that perimenopause, women’s reproductive transition period to menopause, is the critical time when the increase in cardiovascular risk seems magnified.

“When we compared women’s LE8 scores to the premenopausal baseline, the perimenopausal group was the first to show a significant jump in the odds of having low heart health.”

Arora added that nutrition could be an important area for early intervention.

“Nutrition can be a central factor for early and proactive intervention.

“Focusing on heart-healthy habits early, especially getting regular exercise and following a healthy eating plan like the DASH diet with a focus on lowering salt can help improve cardiovascular health for perimenopausal women in the years to come.”

Stacey E. Rosen, volunteer president of the American Heart Association, who was not involved in the study, said the findings underline the need to consider women-specific risk factors across life stages.

“This research highlights yet another aspect of the unique factors that increase a woman’s risk of cardiovascular disease throughout the stages of her lifespan.

“Significant health changes during pregnancy, perimenopause and menopause make it particularly important to pay close attention to increases in health risk factors during those times.

“I encourage women to talk with their primary care and specialty health care teams to learn about early detection and modification of traditional and ‘female-specific’ risk factors.

“Women can take proven steps to improve their cardiovascular health at all ages.”

The researchers said the next step is to follow women over several years to track hormone levels and heart health, which may help clarify the long-term impact of perimenopause and how lifestyle changes could reduce risk.

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Osteoporosis significantly increases risk of death in menopause, study suggests

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Osteoporosis may raise the risk of death in postmenopausal women by up to 47 per cent, a new study suggests.

The findings point to an inverse relationship between femoral bone mineral density and mortality risk, especially within certain ranges.

Femoral bone mineral density is the amount of mineral in the thigh bone, which is often measured to assess bone strength and osteoporosis risk.

Dr Monica Christmas is associate medical director for The Menopause Society.

She said: “Osteoporosis often remains a silent threat after menopause, despite its profound effect on women’s lives—from loss of height, poor balance, and reduced mobility to disfigurement, pain, and even premature death.

“Early screening and preventive measures, including a calcium-rich diet (preferably from food sources), regular weight-bearing exercise, and hormone therapy when appropriate, can significantly improve bone health and reduce risks not only of fractures but also cardiovascular disease, certain cancers, and dementia.

“It’s time we bring this conversation to the forefront.”

In the  study involving nearly 3,000 postmenopausal women, bone mineral density at four femoral sites was assessed using dual-energy x-ray absorptiometry, a scan commonly used to measure bone strength and fracture risk.

The analysis found that mortality risk was significantly higher when femoral bone mineral density reached the osteoporotic threshold or when osteoporotic fractures were present.

After full adjustment, osteoporosis was associated with a 47 per cent increased risk of mortality.

A stronger inverse association between increased bone mineral density and mortality risk was seen within specific ranges, suggesting bone mineral density could serve as a prognostic marker of wider health.

The relationship appeared especially notable within the range of 0.46 to 0.71 g/cm² for total femur bone mineral density.

Previous research has shown that postmenopausal women face a significantly higher risk of death within one year of hip or vertebral fractures.

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