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Hormonal health

Straight talk: Why we need to talk about hormones beyond reproduction

Knowing that our hormones are fluctuating in a healthy pattern is important at any life stage

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When we say hormones, we often think about the reproductive hormones testosterone and oestrogen. Very few know that hormones are, in fact, responsible for every function in our bodies.

Hormones are chemicals secreted by our glands in order to send “messages” through the bloodstream, simply letting the body know what to do to run smoothly. Indeed, they regulate growth, sex drive, reproduction and metabolism, but they are also integral to our digestive, immune, urinary, nervous, cardiovascular, respiratory and skeletal systems.

When it comes to hormonal fluctuations – during menstruation and beyond – experts agree that there is a big education gap. A report published by the female-founded cycle company Fewe found that, of the 2,000 participants interviewed, more than half believed the menstrual cycle was just one week long, while 90 per cent did not see a correlation between their hormones and their health. The same number did not consider management of hormones as an important way to improve their health and wellness.

“What really surprises me is that even us, as women, don’t understand our hormones,” says Sarah Bolt, founder of the biomarker tracking platform, Forth. “Often hormones are talked about in relation to reproduction, but they are so important to our everyday health.”

The lack of knowledge is even more prevalent in regard to perimenopause and menopause. “The two are used very much interchangeably,” Bolt explains. “We see more conversations around periods, but there’s still such a long way to go. Menopause is getting a lot of publicity at the moment, helped by figures like Davina McCall and her recent programme, but we know we need to do a lot more to educate women about the importance of their hormones, how they fluctuate and how they impact all areas of their health. It’s not just about having children.”

Her company, Forth, offers a full range of tests – from liver function tests to immune system, thyroid and hormone tests, providing detailed insights and advice on how to help your body perform to its best. MyFORM, a female hormone mapping test available to women who want to check if their hormones are fluctuating in the correct pattern, is one of them.

The test is suitable for women who want to check their fertility, identify or manage a hormone-related condition such as polycystic ovary syndrome (PCOS), but also for those wanting to check if their hormone network is healthy or for sportswomen who may be at risk of relative energy deficiency in sport (RED-S).

The idea behind the at-home test came after Sarah, working for the NHS, noticed how often women’s symptoms and hormonal imbalances were ignored. “Women were not being listened to particularly during perimenopause and menopause,” the founder tells me. “Our chief medical officer, Dr Nicky Keay, is an endocrinology specialist and she was frustrated because the tests at that time  were not able to capture whether a woman’s hormones were fluctuating in the correct pattern during the entire length of her cycle.

“I myself had been going through perimenopause and I listened to all of my friends going through it. Very often they weren’t being given the correct information by GPs or they ended up being put on antidepressants. So, we decided to look at how we could come up with a solution.”

By combining blood analysis and information about your cycle length, the hormone test mathematically maps how each of your four ovarian hormones fluctuate across your entire cycle and it gives you a detailed, personalised report with next step actions.

MyFORM home kit

“Knowing that your hormones are fluctuating in the healthy correct pattern is important at any life stage and for general wellbeing,” Bolt points out. “So, our bigger goal is to educate women about these hormones and how important they are to their everyday well-being. We recognise those who are on fertility journeys, but we also look at women experiencing conditions like PCOS that they may not even know about.”

MyFORM can also be particularly useful for women who are doing a lot of exercise and who can develop relative energy deficiency syndrome that causes fatigue, low energy, disordered eating, menstrual dysfunction and low bone mineral density.

“Their periods just stop completely,” the founder says. “And that really starts to compromise their health. If you’ve got an imbalance in energy in and energy out, your body will start to go into survival mode. The test identifies if there is a drop in hormones and help you understand the relationship between those variations and how you feel.”

Once they order the blood test, women need to collect a sample on day 14 and day 21 of their cycle and then post it back to the company’s lab. The results are then available on their online account within two working days. Sarah says that women are very surprised when they get the results, because they’ve never been given this kind of information before. “They find it really insightful.”

She tells me that the next step is to expand Forth beyond the UK and develop “an ecosystem” that takes care of women’s health. “I’m also hoping to raise more awareness and help women spot some of the conditions that they might have,” the founder continues. “One of the things that women don’t realise is that the drop in their hormones can really impact their bone health. That is why athletes, for example, have a drop in their hormones and get more injury-prone, because their bone health becomes compromised. That is also why many women develop osteoporosis post-menopause.

“So, we want to open up this conversation because it’s just a natural part of women’s life. There’s nothing embarrassing. Why would it?”

News

Opinion: Women don’t need a refreshed health strategy – we need action

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By Justyna Strzeszynska, founder of menstrual health platform Joii

The Government’s announcement that it will renew the Women’s Health Strategy is, on the surface, good news.

The original strategy in 2022 was historic – the first time women’s health had been acknowledged as something that required its own plan.

It raised awareness, started conversations and encouraged women to come forward and talk about their health.

But awareness alone hasn’t changed much on the ground.

Women are still waiting years for diagnoses, gynaecology waiting lists are still some of the longest in the NHS and many women are still being told their symptoms are ‘just part of being a woman’, especially when it comes to periods, pain or fatigue.

If the Government is going to refresh this strategy, we need to be honest about what didn’t work last time and what has to change now.

One issue with the previous strategy was the way it focused on specific conditions.

Endometriosis and PCOS were rightly brought forward and the advocacy behind that has been extraordinary. But women’s health can’t work like a spotlight, where each year a new condition is added based on who campaigns most effectively.

Some of the most common and life-disrupting conditions still sit in the background.

Heavy menstrual bleeding affects one in three women. Fibroids affect up to one in three by age 50. Adenomyosis is thought to affect one in ten.

These aren’t rare conditions, they are everyday realities. Yet they receive less attention, less funding and far fewer structured care pathways.

They also disproportionately affect Black women, who are more likely to have severe symptoms and less likely to be believed.

If a renewed Women’s Health Strategy is going to address inequality, then these conditions can’t remain an afterthought.

The other major issue is how diagnosis actually happens.

Right now, if you go to your GP with heavy bleeding or pelvic pain, the first questions are usually ‘how much blood do you think you’re losing?’ and ‘how bad is the pain, on a scale of 1 to 10?’

Most women have never been taught what ‘normal’ bleeding looks like and their pain has become background noise. Many also feel unsure or embarrassed about describing symptoms accurately.

So women hesitate, clinicians hesitate and referrals get delayed. That’s how we end up with eight-year diagnostic journeys.

If we want to reduce waiting lists and speed up diagnosis, we need to fix the front door.

First, we need to give GPs standardised tools to measure menstrual bleeding and symptom impact.

One of the biggest barriers to diagnosing menstrual health conditions is that we still rely on women to estimate their bleeding and pain with no reference points.

Most women, and especially young girls, don’t know what counts as heavy bleeding and many have normalised symptoms that could actually be clinical red flags.

Without standard measurement, clinicians can’t triage effectively and women fall into long cycles of ‘wait and see’.

The renewed strategy should introduce validated digital and clinical tools, so patients and clinicians are working from the same evidence, not guesswork.

Second, expand and standardise Women’s Health Hubs so access isn’t determined by postcode.

Women’s Health Hubs already exist in most of England, which is a strong start, but not all hubs offer the same services, capacity or quality of care.

Some are genuinely transformative while others function more as signposting centres.

To actually reduce the backlog and speed up diagnosis, hubs need to be properly resourced and consistent, with clear referral pathways from primary care.

The refreshed strategy should set national standards for what every hub must deliver so accessing timely assessment isn’t dependent on where a woman happens to live.

Finally, there needs to be a shift towards treating menstrual and pelvic conditions as chronic, not occasional episodes.

Conditions like endometriosis, adenomyosis, fibroids, PCOS and chronic pelvic pain don’t follow single-appointment cycles yet our system is structured as if they do.

Women are often seen once, reassured and discharged, only to start the entire referral process again when symptoms worsen. This wastes NHS time and leaves women feeling unheard.

The renewed strategy needs to support ongoing monitoring and follow-up, recognising these conditions as long-term health issues requiring continuous management, not episodic care.

Most importantly, the refreshed strategy must come with clear timelines, ringfenced funding and actual accountability.

Otherwise, we end up with another web page and a press release, instead of change.

Women are already doing their part by speaking up.

Now the system needs to meet them.

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Entrepreneur

AI-powered women’s health companion Nexus launches in UK

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The first AI-powered health companion designed exclusively for women is launching in the UK today.

Nexus provides a unified fitness, nutrition, medication and cycle tracking solution alongside a personal digital health coach.

Unlike other health apps built for isolated concerns, Nexus recognises that women’s health is interconnected.

Powered by a proprietary AI model and guided by Nova, the in-app AI health coach, Nexus connects the dots between every aspect of a woman’s wellbeing, from hormonal cycles to nutrition and mental health, and provides personalised, evidence-based guidance in real time.

Co-founder Leo Tyson has worked with over a thousand women in his role as a personal health coach, but wanted to support even more women through their health journeys.

Tyson said: “Nexus gives every woman a health coach in her pocket and the knowledge to become her own expert.

“I would see women desperate for guidance but unable to afford one-on-one coaching.

“They would try to patch together information from different apps or cheaper coaches, often making things worse rather than better.

“At the same time, the sector has been missing an integrated platform that understands women’s health is not just their cycles, but their whole health story.

“Our mission with Nexus is to give every woman at every life stage the personalisation, clarity and support of a one-to-one health coaching, at an accessible price.”

The launch draws on extensive research in Nexus’ white paper The Period App Problem, which revealed that many women feel disappointed by menstrual tracking apps that fail to deliver meaningful, personalised insights.

Nexus bridges this gap with a female-specific onboarding process offering over 50,000 unique combinations of personalised wellness insights.

With Nova, users also have access to an AI coach that truly knows them, offering adaptive, actionable guidance grounded in science and tailored to each woman’s unique physiology and life stage.

The vision behind Nexus is to give women control over their own health data, using it to improve conversations with healthcare providers, reduce medical gaslighting and accelerate diagnosis times through advocacy and education.

At the heart of Nexus lies a proprietary large language model (LLM) and peer-reviewed health database, built specifically for women.

This architecture blends medical research, clinical guidelines and user data to generate precise recommendations, far surpassing the capabilities of off-the-shelf AI systems.

Nexus is available on the App Store from today (10th October).

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Mental health

Black and Latinx women more likely to experience serious complications in planned repeat caesareans

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Black and Latinx women are more likely to face serious complications during planned repeat caesareans than White women, new US research has found.

While complication rates were similar across all racial and ethnic groups for vaginal births after a previous caesarean, disparities emerged in outcomes for those having planned repeat surgery.

Researchers examined severe maternal morbidity – serious complications during childbirth that can have lasting health effects – across 72,836 births between 2012 and 2021 among people who had previously delivered by caesarean.

The team analysed data from the Massachusetts Pregnancy to Early Life Longitudinal Data System, focusing on births following an earlier caesarean.

The 21 complications tracked include outcomes such as hysterectomy (removal of the womb), heart attack, embolism (blood vessel blockage), kidney failure, eclampsia (seizures in pregnancy linked to high blood pressure), sepsis (a life-threatening infection), and complications related to anaesthesia.

Laura Attanasio is associate professor of health policy and management and lead author of the study.

She said: “There’s been increasing recognition in recent years that the US has this rising rate of severe maternal morbidity, which can have a negative impact on one’s health in the future.”

It also can be considered a near miss for maternal mortality, or death, which is also high in the US relative to other wealthy countries, though rare.

The study examined three birth scenarios: vaginal birth after caesarean (VBAC), planned repeat caesarean, and unplanned repeat caesarean – where someone intends to deliver vaginally but ultimately requires surgery.

Attanasio said: “Among White birthing people, severe maternal morbidity rates were similar for VBAC and for planned repeat caesarean.

“But for Black and Latinx birthing people, planned repeat caesarean had a higher rate of severe maternal morbidity compared to VBAC.”

Among all groups, the highest rate of complications occurred during unplanned repeat caesareans.

In this category, however, disparities between racial and ethnic groups were not observed.

The study population was 56.8 per cent White, 20.1 per cent Latinx, 11 per cent Black and 12.1 per cent who identified as another race or ethnicity.

The researchers used hospital discharge and birth records to identify medical issues and demographic data including race, ethnicity and parental birthplace.

They adjusted for medical risk factors more commonly associated with marginalised groups, suggesting other influences may be contributing to the differences in outcomes.

Attanasio hypothesised that “quality of clinical care can be worse for people from marginalised racial and ethnic groups, either because they’re being cared for in settings that are lower resourced and less able to provide quality care, or in some cases they could be receiving worse care in the same setting as White birthing people due to structural or interpersonal racism.”

The findings suggest the need to identify and address factors contributing to higher complication rates among Black and Latinx individuals during planned repeat caesareans.

“Future work should identify interventions to improve quality of care and promote equity for this population,” the researchers said.

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